Investigation of volatile oil contents and some ecological characteristics of wild and cultivated Sideritis stricta Boiss. & Heldr.
DOI:
https://doi.org/10.56782/pps.255Keywords:
Sideritis stricta, volatile oil content, ecology, endemicAbstract
The indiscriminate removal of medicinal and herbal plants from their natural habitats, the colonization of alien and invasive species in the habitats where these valuable plant species grow, the decrease in the purity rates of plants, and the extinction of plant species make these types of plants vulnerable to threats. The cultivation of such valuable plant species can prevent such situations. However, it remains a subject of interest for ecologists whether cultivated plants undergo any loss of characteristics due to these factors. In this study, the endemic medicinal plant Sideritis stricta Boiss. & Heldr. was utilized to shed light on this matter. The volatile oil contents of two wild forms (Kemer: W1 and Serik: W2) and one cultivated form (Kaş: C) of the species were compared, and environmental factors believed to influence volatile oil content were examined. The analysis results revealed that the major components (α-pinene, β-pinene, and caryophyllene) were mostly present in similar amounts. β-pinene was found to be the predominant compound in C, W1, and W2 samples, with percentages of 32.28%, 27.33%, and 40.61%, respectively. All volatile oils were found to be rich in monoterpenes. The humidity and soil pH values in the cultivation area differed from the natural habitats of the wild samples, and these factors had an impact on volatile oil yield and composition. Consequently, when conducting cultivation studies on a species, it is essential to adapt the natural form of the species to cultivation conditions by closely observing the environmental factors.
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References
The State of the World’s Plants Reports, Kew, London: Royal Botanic Gardens, 2016. https://stateoftheworldsplants.org/2016, Accessed 02.05.2016.
Wills, K.J. State of the World’s Plants 2017 Report 2017. Kew, London: Royal Botanic Gardens. https://stateoftheworldsplants.org, Accessed 14.05.2017.
Güner, A.; Aslan, S.; Vural, M. & Babaç, M.T. Türkiye Bitkiler Listesi (Damarlı Bitkiler). İstanbul, Turkey: Nezahat Gökyiğit Botanik Bahçesi ve Flora Araştırmaları Derneği 2012, 210-215.
Özhatay, N.; Kültür, Ş. & Gürdal, B. Check-list of Additional Taxa to the Supplement Flora of Turkey IX. Istanbul J. Pharm. 2019, 49(2), 105-120. DOI: 10.26650/IstanbulJPharm.2019.19037. DOI: https://doi.org/10.26650/IstanbulJPharm.2019.19037
Gülcan, Z.; Saltan, N.; İşcan, G.; Kürkçüoğlu, M. & Köse, Y.B. Antimicrobial and antioxidant activities of Sideritis lanata L. extracts. Eur. J. Life Sci. 2022, 1(2), 63-79. DOI: https://doi.org/10.55971/EJLS.1181461 DOI: https://doi.org/10.55971/EJLS.1181461
Davis, P.H. Flora of Turkey and the East Aegean Islands, Edinburgh University Press, Edinburgh, 1982, 7, 252-271.
Güner, A.; Özhatay, N.; Ekim, T.; Başer, K.H.C.; Hedge, I. C. Flora of Turkey and East Aegean Islands, 2000, 11(2), Edinb. Univ. Press., Edinburgh.
Duman, H.; Kırımer, N.; Ünal, F.; Güvenç, A. & Şahin, P. Türkiye Sideritis L. Türleri’nin Revizyonu, Project Report, 2005, Ankara, Turkey.
Erdem, F. Sideritis vulcanica Hub.-Mor. (Lamiaceae) Türünün (Endemik) Taksonomik Yönden İncelenmesi, (Thesis no: 348497). Master’s thesis, Firat University Institute of Science, 2013.
Mohammed, F. S.; Akgul, H.; Sevindik, M. & Khaled, B.M.T. Phenolic Content and Biological Activities of Rhus coriaria var. zebaria. Fresen. Environ. Bull. 2018, 27(8), 5694-5702.
Mohammed, F. S.; Günal, S.; Şabik, A. E.; Akgül, H. & Sevindik, M. Antioxidant and Antimicrobial Activity of Scorzonera papposa Collected from Iraq and Turkey. KSU J. Agric. Nat. 2020, 23(5), 1114-1118. DOI: 10.18016/ksutarimdoga.vi.699457 DOI: https://doi.org/10.18016/ksutarimdoga.vi.699457
Sevindik, M.; Akgul, H.; Pehlivan, M. & Selamoglu, Z. Determination of Therapeutic Potential of Mentha longifolia ssp. longifolia. Fresen. Environ. Bull. 2017, 26(7), 4757-4763.
Mohammed, F. S.; Karakaş, M.; Akgül, H. & Sevindik, M. Medicinal Properties of Allium calocephalum Collected from Gara Mountain (Iraq). Fresen. Environ. Bull. 2019, 28(10), 7419-7426.
Mohammed, F. S.; Pehlivan, M.; Sevindik, E.; Akgul, H.; Sevindik, M.; Bozgeyik, I. & Yumrutas, O. Pharmacological Properties of Edible Asparagus acutifolius and Asparagus officinalis Collected from North Iraq and Turkey (Hatay). Acta Aliment. Hung. 2021, 50(1), 136-143. DOI: 10.1556/066.2020.00204 DOI: https://doi.org/10.1556/066.2020.00204
Sevindik, M.; Akgul, H.; Akata, I.; Alli, H. & Selamoglu, Z. Fomitopsis pinicola in Healthful Dietary Approach and Their Therapeutic Potentials. Acta Aliment. Hung. 2017, 46(4), 464-469. DOI: 10.1556/066.2017.46.4.9 DOI: https://doi.org/10.1556/066.2017.46.4.9
Korkmaz, A. I.; Akgul, H.; Sevindik, M. & Selamoglu, Z. Study On Determination of Bioactive Potentials of Certain Lichens. Acta Aliment. Hung. 2018, 47(1), 80-87. DOI: 10.1556/066.2018.47.1.10 DOI: https://doi.org/10.1556/066.2018.47.1.10
Sevindik, M.; Rasul, A.; Hussain, G.; Anwar, H.; Zahoor, M. K.; Sarfraz, I., Kamran, K.S., Akgül, H., Akata, I. & Selamoglu, Z. Determination of Anti-oxidative, Anti-microbial Activity and Heavy Metal Contents of Leucoagaricus leucothites. Pak. J. Pharm. Sci. 2018, 31(5), 2163-2168.
Sevindik, M.; Akgul, H.; Bal, C. & Selamoglu, Z. Phenolic contents, oxidant/antioxidant potential and heavy metal levels in Cyclocybe cylindracea. Ind. J. Pharm. Edu. Res. 2018, 52(3), 437-441. DOI: 10.5530/ijper.52.3.50 DOI: https://doi.org/10.5530/ijper.52.3.50
Eraslan, E. C.; Altuntas, D.; Baba, H.; Bal, C.; Akgül, H.; Akata, I. & Sevindik, M. Some biological activities and element contents of ethanol extract of wild edible mushroom Morchella esculenta. Sigma J. Eng. Nat. Sci. 2021, 39(1), 24-28.
Özhatay, N.; Koyuncu, M.; Atay, S. & Byfield, A. Türkiye'nin Doğal ve Tıbbi Bitkilerinin Ticareti Hakkında Bir Çalışma. Doğal Hayatı Koruma Derneği, İstanbul, 1997.
Küpeli, E.; Sahin, P.; Calis, I.; Yeşilada, E. & Ezer, N. Phenolic Compounds of Sideritis ozturkii and Their in vivo Anti-inflammatory and Antinociceptive Activities. J. Ethnopharmacol. 2007, 112, 356-60. DOI: 10.1016/j.jep.2007.03.017 DOI: https://doi.org/10.1016/j.jep.2007.03.017
-Turkmenoglu, F.; Baysal, I.; Ciftci-Yabanoglu, S.; Yelekci, K.; Temel, H.; Pasa, S.; Ezer, N.; Çalış, I. & Uçar, G. Flavonoids from Sideritis Species: Human Monoamine Oxidase (hMAO) Inhibitory Activities, Molecular Docking Studies and Crystal Structure of Xanthomicrol. Molecules 2015, 20, 7454-7473. DOI: 10.3390/molecules20057454 DOI: https://doi.org/10.3390/molecules20057454
Erdoğan, A.; Özkan, A.; Ünal, O. & Dülgeroğlu, C. Evaluation of the Cytotoxic and Membrane Damaging Effects of Mountain Tea (Sideritis stricta Boiss & Heldr.) Essential Oil on Parental and Epirubicin-HCl Resistant H1299 Cells. Cukurova Med. J. 2018, 43(3), 669-677. DOI: https://doi.org/10.17826/cumj.340273
Aneva, I.; Zhelev, P.; Kozuharova, E.; Danova, K.; Nabavi, S.F. & Behzad, S. Genus Sideritis, Section Empedoclia in Southeastern Europe and Turkey – Studies in Ethnopharmacology and Recent Progress of Biological Activities. DARU 2019, 27, 407-421. DOI: 10.1007/s40199-019-00261-8 DOI: https://doi.org/10.1007/s40199-019-00261-8
Uçar, E. & Turgut, K. Bazı Dağ Çayı (Sideritis) Türlerinin in vitro Çoğaltımı. Akdeniz University Journal of the Faculty of Agriculture 2009, 22(1), 51-57.
Lubbe, A. & Verpoorte, R. Cultivation of Medicinal and Aromatic Plants for Specialty Industrial Materials. Ind. Crops Prod. 2011, 34 (1), 785-801. DOI: 10.1016/j.indcrop.2011.01.019 DOI: https://doi.org/10.1016/j.indcrop.2011.01.019
Bouyoucos, G.J. A Recalibration of the Hydrometer Method for Making Mechanical Analysis of the Soil. Agron. J. 1995, 43(9), 434. DOI: 10.2134/agronj1951.00021962004300090005x DOI: https://doi.org/10.2134/agronj1951.00021962004300090005x
Steubing, B.L. Pflanzenökologisches Praktium. Verlag Paul Parey. 1965, Berlin, Hamburg, Germany.
Jackson, M.L. Soil Chemical Analysis. New Delhi, India: Prentice-Hall of India Pvt. Ltd., 1962.
Çağlar, K.Ö. Toprak Bilgisi, Ankara, Turkey: Ankara Üniversitesi Ziraat Fakültesi Yayınları, Vol. 10, 1949.
Black, C.A. Methods of Soil Analysis, Part 2, Wisconsin, USA: Amer. Society of Agronomy Inc., Publisher Madison, 1965.
Kaçar, B. Plant and Soil Analysis, University of Nebraska College of Agriculture, Department of Agronomy, Lincoln, Nebraska, USA, 1962.
Olsen, S.R. & Sommers, L.E. Phosphorus Availability Indices. Phosphorus Soluble in Sodium Bicarbonate. In: Page AL, Miller RH, Keeney DR (editors), Method of Soil Analysis, Chemical and Microbiological Properties, 1982, Part 2, Wisconsin, USA: American Society of Agronomy, 404-430. DOI: https://doi.org/10.2134/agronmonogr9.2.2ed.c24
Lindsay, W.L. & Norwell, W.A. Development of a DTPA Soil Test for Zing, Iron, Manganese and copper. SSSA 1978, 42 (3), 421-428. DOI: 10.2136/sssaj1978.03615995004200030009x. DOI: https://doi.org/10.2136/sssaj1978.03615995004200030009x
Flamini, G.; Cioni, P. L.; Morelli, I.; Celik, S.; Gokturk, R. S. & Unal, O. Essential Oil of Stachys aleurites From Turkey. Biochem. Syst. Ecol. 2005, 33(1), 61-66. DOI: 10.1016/j.bse.2004.05.013 DOI: https://doi.org/10.1016/j.bse.2004.05.013
Ozkan, G.; Sagdic, O.; Gokturk, R. S.; Unal, O. & Albayrak, S. Study on Chemical Composition and Biological Activities of Essential Oil and Extract From Salvia pisidica. LWT-Food Sci. Technol. 2010, 43(1), 186-190. DOI: 10.1016/j.lwt.2009.06.014 DOI: https://doi.org/10.1016/j.lwt.2009.06.014
Demir, F. T. & Yavuz, M. Heavy metal accumulation and genotoxic effects in levant vole (Microtus guentheri) collected from contaminated areas due to mining activities. Environ. Pollut. 2020, 256, Art. No: 113378. DOI: 10.1016/j.envpol.2019.113378 DOI: https://doi.org/10.1016/j.envpol.2019.113378
Kırımer, N.; Tabanca, N.; Ozek, T.; Başer, K.H.C. & Tümen, G. Composition of Essential Oils From Five Endemic Sideritis species. JEOR 2003, 15, 221-225. DOI: 10.1080/10412905.2003.9712125. DOI: https://doi.org/10.1080/10412905.2003.9712125
Deveci, E.; Tel Çayan, G. & Duru, M.E. Essential Oil Composition, Antioxidant, Anticholinesterase and Anti-tyrosinase Activities of Two Turkish Plant Species: Ferula elaeochytris and Sideritis stricta. Nat. Prod. Comm. 2018, 13(1), 101-104. DOI: 10.1177/1934578X1801300130 DOI: https://doi.org/10.1177/1934578X1801300130
Özkan, G.; Krüger, H.; Schulz, H. & Özcan, M. Essential Oil Composition of Three Sideritis Species Used As Herbal Teas in Turkey. J. Essent. Oil Bear. Pl. 2005, 8(2), 173-177. DOI: 10.1080/0972060X.2005.10643439 DOI: https://doi.org/10.1080/0972060X.2005.10643439
Özcan, M.; Chalchat, J.C. & Akgül, A. Essential Oil Composition of Turkish Mountain Tea (Sideritis spp.). Food Chem. 2001, 75, 459-463. DOI: 10.1016/S0308-8146(01)00225-4 DOI: https://doi.org/10.1016/S0308-8146(01)00225-4
Pljevljakusic, D.; Savikin, K.; Jankovic, T.; Zdunic, G.; Ristic, M. Chemical Properties of the Cultivated Sideritis raeseri Boiss. & Heldr. subsp. raeseri. Food Chem. 2011, 124, 226–233. DOI: 10.1016/j.foodchem.2010.06.023 DOI: https://doi.org/10.1016/j.foodchem.2010.06.023
Başer, K.H.C.; Özek, T.; Tümen, G.; Karaer, F. Essential Oil Composition of Three Labiatae Endemic to Turkey (Micromeria fruticosa (L.) Druce subsp. giresunica P.H. Davis, Sideritis lycia Boiss et Heldr. and S.arguta Boiss et Heldr.). JEOR 1996, 8, 699-701. DOI: 10.1080/10412905.1996.9701048 DOI: https://doi.org/10.1080/10412905.1996.9701048
Aligiannis, N.; Kalpoutzakis, E.; Chinou, I.B.; Mitakou, S.; Gikas, E. & Tsarbopoulos, A. Composition and Antimicrobial Activity of The Essential Oils of Five Taxa of Sideritis From Greece. J. Agric. Food Chem. 2001, 49(2), 811-815. DOI: 10.1021/jf001018w DOI: https://doi.org/10.1021/jf001018w
Tabanca, N.; Kırımer, N. & Başer, K.H.C. The Composition of Essential Oils from Two Varieties of Sideritis erythrantha var. erythrantha and var. cedretorum. Turk. J. Chem. 2001, 25, 201-208.
Başer, K.H.C. Aromatic Biodiversity Among The Flowering Plant Taxa of Turkey. Pure Appl. Chem. 2002, 74, 527-545. DOI: 10.1351/pac200274040527 DOI: https://doi.org/10.1351/pac200274040527
Kirimer, N.; Başer, K.H.C.; Demirci, B. & Duman, H. Essential Oils of Sideritis Species of Turkey Belonging to the Section Empedoclia. Chem. Nat. Compd. 2004, 40, 19-23. DOI: 10.1023/B:CONC.0000025458.00475.cf DOI: https://doi.org/10.1023/B:CONC.0000025458.00475.cf
Topçu, G.; Barla, A.; Gören, A.C.; Bilsel, G.; Bilsel, M. Analysis of the Essential Oil Composition of Sideritis albiflora Using Direct Thermal Desorption and Headspace GC-MS Techniques. TurK. J. Chem. 2005, 29, 525-529
Özel, M.Z.; Lewis, A.C. & Göğüş, F. Chemical Composition of Volatiles From Leaves and Flowers of Sideritis congesta using Direct Thermal Desorption-Two-Dimensional Gas Chromatography Time of Flight Mass Spectrometry. J. Essent. Oil Bear. Pl. 2008, 11, 22-29. DOI: 10.1080/0972060X.2008.10643592 DOI: https://doi.org/10.1080/0972060X.2008.10643592
Erbaş, S. & Fakir, H. Determination of Contents and Components of Essential Oils of Sideritis libanotica Labill. Subsp. Linearis (Bentham) Bornm. And Origanum Sipyleum L. Grown Wild In Western Mediterranean Region Of Turkey. SDU Faculty of Forestry J. 2012, 13, 119-122.
Bilginoğlu, E. Determination of Quality Criteria of Cultivated Endemic Sideritis stricta Boiss. & Heldr. and Sideritis congesta Davis & Huber-Morath (Lamiaceae) Species, (Thesis no:607171) The Graduate School of Natural and Applied Science, Selçuk University, Department of Field Crops, PhD Thesis, 2019.
Fraga, B.M. Phytochemistry and Chemotaxonomy of Sideritis Species from the Mediterranean Region. Phytochemistry 2012, 76, 7-24. DOI: 10.1016/j.phytochem.2012.01.018 DOI: https://doi.org/10.1016/j.phytochem.2012.01.018
Palá‐Paúl, J.; Pérez‐Alonso, M.J.; Velasco‐Negueruela, A.; Ballesteros, M.T. & Sanz, J. Essential Oil Composition of Sideritis hirsuta L. from Guadalajara Province, Spain. Flavour Frag. J. 2006, 21 (3), 410-415. DOI: 10.1002/ffj.1727 DOI: https://doi.org/10.1002/ffj.1727
Giuliani, C.; Maleci Bini, L.; Papa, F.; Cristalli, G.; Sagratini, G.; Vittori, S.; Lucarini, D. & Maggi, F. Glandular Trichomes and Essential Oil Composition of Endemic Sideritis italica (Mill.) Greuter et Burdet from Central Italy. Chem. Biodiver. 2011, 8(12), 2179-2194. DOI: 10.1002/cbdv.201000290 DOI: https://doi.org/10.1002/cbdv.201000290
Semiz, G. & Özel, M.Z. Essential Oil Composition of Endemic Sideritis leptoclada O. Schwarz & PH Davis (Lamiaceae) from Turkey by Using Two-Dimensional Gas Chromatography-Time-of-Flight Mass Spectrometry (GCxGC-TOF/MS). Int. J. Sec. Metabolite, 2017, 4(2), 137-141. DOI: 10.21448/ijsm.309535. DOI: https://doi.org/10.21448/ijsm.309535
Dincer, C.; Topuz, A.; Nadeem, H.S.; Ozdemir, K.S.; Cam, I.B.; Tontul, I.; Gokturk, R.S. & Tugrul Ay, S. A Comparative Study on Phenolic Composition, Antioxidant Activity and Essential Oil Content of Wild and Cultivated Sage (Salvia Fruticosa Miller) As Influenced By Storage, Ind. Crops Prod. 2012, 39, 170-176. DOI: 10.1016/j.indcrop.2012.02.032 DOI: https://doi.org/10.1016/j.indcrop.2012.02.032
Kasrati, C.; Alaoui Jamali, K.; Bekkouche, H., Lahcen, M.; Markou, H.; Wohlmuth, D. & Leach Abbad, A. Essential Oil Composition and Antimicrobial Activity of Wild and Cultivated Mint Timija (Mentha suaveolens subsp. timija (Briq.) Harley), an Endemic and Threatened Medicinal Species in Morocco, Nat. Prod. Res. 2013, 27(12), 1119-1122. DOI: 10.1080/14786419.2012.708661. DOI: https://doi.org/10.1080/14786419.2012.708661
Farsam, H.; Amanlou, M.; Radpour, M.R.; Salehinia, A.N. & Shafiee, A. Composition of the Essential Oils of Wild and Cultivated Satureja khuzistanica Jamzad from Iran. Flavour Frag. J. 2004, 19, 308-310. DOI: 10.1002/ffj.1300 DOI: https://doi.org/10.1002/ffj.1300
Gotsiou, P.; Naxakis, G. & Skoula, M. Diversity in the Composition of Monoterpenoids of Origanum microphyllum (Labiatae). Biochem. Syst. Ecol. 2002, 30, 865–879. DOI: 10.1016/S0305-1978(02)00025-X DOI: https://doi.org/10.1016/S0305-1978(02)00025-X
Bilginoğlu, E. Konya Ekolojik Şartlarında Farklı Gübre Dozlarına Göre Yetiştirilen Dağçayı Türlerinin (Sideritis) Kurutma Yöntemlerine Göre Drog Verimi ve Bazı Kalite Özellikleri Üzerine Etkileri, (Thesis no: 380876) Department of Field Crops, Faculty of Science, Selçuk University, Master’s Thesis, 2015.
Cabo, J.; Crespo, M.E.; Jimenez, J.; Navarro, C. & Risco, S. Seasonal Variation of Essential Oil Yield and Composition of Thymus hyemalis. Planta Med. 1987, 53(4), 380-382, DOI: 10.1055/s-2006-962744 DOI: https://doi.org/10.1055/s-2006-962744
Kokkini, S. Taxonomy, Diversity and Distribution of Origanum spp. Proceeding of the IPGRI International Workshop on Oregano. 8-12 May 1996. CIHEAM, Valenzano, Bari, Italy. Ed.: S. Padulosi, 2-12.
Kokkini, S.; Karausou, R.; Dardioti, A.; Krigos, N. & Lanoros, T. Autumn Essential Oils of Greek Oregano. Phytochemistry 1997, 44, 883-886. DOI: https://doi.org/10.1016/S0031-9422(96)00576-6. DOI: https://doi.org/10.1016/S0031-9422(96)00576-6
Turgut, K. & Tuğrul Ay, S. Essential Oil and Carvacrol Content of Oregano (Origanum spp.) Species Grown in Wild and Cultivated Conditions of Antalya. Afr. J. Tradit. Complement. Altern. Med. 2009, 6, 355-355.
Peer, W.A. & Langenheim, J.H. Influence of Phytochrome on Leaf Monoterpene Variation in Satureja douglasii. Biochem. Syst. Ecol. 1998, 26(1), 25-34. DOI: 10.1016/S0305-1978(97)00076-8 DOI: https://doi.org/10.1016/S0305-1978(97)00076-8
Hornok, L. Influence of Nutrition on the Yield and Content of Active Compounds in Some Essential Oil Plants. Acta Hortic. 1983, 132, 239-247. DOI: 10.17660/ActaHortic.1983.132.26 DOI: https://doi.org/10.17660/ActaHortic.1983.132.26
Kocabaş, I.; Sönmez, I.; Kalkan, H. & Kaplan, M. Farklı Organik Gübrelerin Adaçayı (Salvia fructicosa Mill.)’Nın Uçucu Yağ Oranı ve Bitki Besin Maddeleri Içeriğine Etkileri. Akdeniz Üniversitesi Ziraat Fakültesi Dergisi, 2007, 20(1), 105-110.
Circella, G.; Franz, C.; Novak, J. & Resch, H. Influence of Day Length and Leaf Insertion on The Composition of Marjoram Essential Oil. Flavour Frag. J. 1995, 10(6), 371-374. DOI: 10.1002/ffj.2730100607 DOI: https://doi.org/10.1002/ffj.2730100607
Marzi, V. Agricultural Practices for Oregano, In: Proceedings of IPGRI International Workshop on Oregano; CIHEAM, Valenzano, Bari, Italy, 1996.
Şahi̇n, F.P.; Ezer, N. & Çaliş, I. Terpenic and Phenolic Compounds from Sideritis stricta. Turk. J. Chem. 2006, 30(4), 495-504.
Kloukina, C.; Tomou, E. M. & Skaltsa, H. Essential Oil Composition of Two Greek Cultivated Sideritis spp. NVEO, 2019, 6(3), 16-23.
Gökhan, A. Effects of Essential Oils Obtained from Wild and Cultured Forms of Thyme (Origanum acutidens) On Lung Cancer Cells Membrane. J. Health Sci. Med. 2021, 4(4), 445-450. DOI: 10.32322/jhsm.918748 DOI: https://doi.org/10.32322/jhsm.918748
Gökhan, A. Investigation of the Apoptotic and Membrane Effects of Essential Oils Obtained from Wild and Cultured Forms of Origanum acutidens (Hand.-Mazz.) Ietswaart on Epidermoid Cancer (A-431) Cells. Pharm. Chem. J. 2022, 56(1), 85-93. DOI: 10.1007/s11094-022-02603-4 DOI: https://doi.org/10.1007/s11094-022-02603-4
Ünal, O.; Özkaya, S.; Aydemir, E. & Torun, M. Farklı Yıllarda Toplanan Benli Şalba (Salvia pisidica Boiss. & Heldr. ex Bentham) Türünün Sitotoksik Etkisinin Araştırılması. KSU J. Agric. Nat. 2023, 26(6), 1268-1276. DOI: 10.18016/ksutarimdoga.vi.1205655 DOI: https://doi.org/10.18016/ksutarimdoga.vi.1205655
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