Evaluation of the effectiveness of platelet-rich plasma therapy in the treatment of osteoarthritis compared to other treatment methods

Katarzyna Łysiak; Anna Łysiak; Magdalena Makarewicz; Barbara Maziarz

doi:10.56782/pps.231

Data publikacji : 2024-10-29

Tom 22 Nr 4 (2024)

Evaluation of the effectiveness of platelet-rich plasma therapy in the treatment of osteoarthritis compared to other treatment methods

Katarzyna Łysiak

Anna Łysiak

Magdalena Makarewicz

Barbara Maziarz

DOI: https://doi.org/10.56782/pps.231

Abstrakt

Introduction and objective: Osteoarthritis is a common condition affecting a large proportion of the population. It is associated with a significant reduction in quality of life due to pain and limited joint mobility. There are many methods of treatment, among them conservative methods, pharmacological or surgical treatment can be mentioned. This article analyzes the effectiveness of intra-articular injections of platelet-rich plasma compared to other methods.

The aim of the article is to characterize the disease which is osteoarthritis, draw attention to its etiology, diagnostic and especially to therapeutic possibilities.

Materials and methods: The article was based on scientific publications in the Pubmed database. The database was searched on July 28 2023 using the phrases 'osteoarthritis', ‘PRP’, ‘Platelet-rich plasma’. After reading the titles of found articles, 39 publications were selected. After the pre-analysis of the abstracts, 15 full-text works were selected to prepare the article.

Abbreviated description of the state of knowledge: Platelet-rich plasma is widely used in the treatment of osteoarthritis. There are many sources that prove its effectiveness in reducing pain, compared to injections of other substances, but there are also studies about the lack of sufficient evidence or the effect of prp similar to the placebo effect.

Summary: The use of platelet-rich plasma is a promising method of treating osteoarthritis, however, further research and long-term observations are needed to introduce this method to the standards of treatment.

Słowa kluczowe:

osteoarthritis; PRP; platelet-rich plasma

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Łysiak, K., Łysiak, A., Makarewicz, M., & Maziarz, B. (2024). Evaluation of the effectiveness of platelet-rich plasma therapy in the treatment of osteoarthritis compared to other treatment methods. Prospects in Pharmaceutical Sciences, 22(4), 39–43. https://doi.org/10.56782/pps.231

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Katarzyna Łysiak

kas.lysiak@gmail.com

Afiliacja:

Stefan Cardinal Wyszynski Provincial Specialist Hospital Independent Public Health Care Center in Lublin, al. Kraśnicka 100, 20-718 Lublin, Poland Poland

Anna Łysiak

ann.lysiak@gmail.com
https://orcid.org/0009-0002-1157-9081

Afiliacja:

Independent Public Clinical Hospital No. 4 in Lublin, ul. Doktora Kazimierza Jaczewskiego 8, 20-954 Lublin Poland

Magdalena Makarewicz

m.makarewicz.97@gmail.com
https://orcid.org/0000-0003-0485-8998

Afiliacja:

Puławy Hospital – Independent Public Health Care Institution, Józefa Bema 1, 24-100 Puławy Poland

Barbara Maziarz

basssmaz@gmail.com
https://orcid.org/0000-0002-8339-1187

Afiliacja:

Independent Public Clinical Hospital named after Prof. Orlowski, Center for Postgraduate Medical Education in Warsaw, ul. Czerniakowska 231, 00-416 Warszawa Poland