Isolation of trachelogenin 4-O-β-D-glucoside from the fruits of Carthamus tinctorius L.

Andrzej Patyra; Marcin Kołakowski; Marta Katarzyna Dudek; Anna Karolina Kiss

doi:10.56782/pps.39

Data publikacji : 2022-08-18

Tom 20 Nr 2 (2022)

Isolation of trachelogenin 4-O-β-D-glucoside from the fruits of Carthamus tinctorius L.

Andrzej Patyra

Marcin Kołakowski

Marta Katarzyna Dudek

Anna Karolina Kiss

DOI: https://doi.org/10.56782/pps.39

Abstrakt

Trachelogenin 4-O-β-D-glucoside or tracheloside is a rare lignan glycoside present mostly in some plants from the Cynarae tribe of the Asteraceae family. As this lignan is also present in small amounts in the human diet, isolation and study of the pharmacological properties of this compound may bring some new insights into the role of lignans. This study aimed to isolate trachelogenin 4-O-β-D-glucoside from the fruits of safflower using chromatographic methods. Briefly, 339 mg of tracheloside was isolated from 500 g of plant material. The yield is sufficient for performing biological studies, thus confirming that safflower fruits are a significant source of this rare compound.

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Patyra, A., Kołakowski, M., Dudek, M. K., & Kiss, A. K. (2022). Isolation of trachelogenin 4-O-β-D-glucoside from the fruits of Carthamus tinctorius L. Prospects in Pharmaceutical Sciences, 20(2), 24–30. https://doi.org/10.56782/pps.39

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Andrzej Patyra

andrzej.patyra@wum.edu.pl
https://orcid.org/0000-0003-4981-6660

Afiliacja:

Department of Pharmacognosy and Molecular Basis of Phytotherapy, Medical University of Warsaw, Warsaw, Poland; Doctoral School, Medical University of Warsaw, Warsaw, Poland; Institut des Biomolécules Max Mousseron, Université de Montpellier, CNRS, ENSCM, Montpellier, France Poland

Marcin Kołakowski

Afiliacja:

Department of Pharmacognosy and Molecular Basis of Phytotherapy, Medical University of Warsaw, Warsaw, Poland Poland

Marta Katarzyna Dudek

Afiliacja:

Structural Studies Department, Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Łódź, Poland Poland

Anna Karolina Kiss

akiss@wum.edu.pl

Afiliacja:

Department of Pharmacognosy and Molecular Basis of Phytotherapy, Medical University of Warsaw, Warsaw, Poland Poland