Outline of the history of drug synthesis with particular emphasis on anticancer and antibacterial drugs
DOI:
https://doi.org/10.56782/pps.121Keywords:
synthesis, antibacterial drugs, anticancer drugsAbstract
The paper presents a historical outline of the development of drugs from the earliest times to the present, trying to take into account the path that has come from learning about the medicinal properties of the raw material, through the identification of specific active compounds isolated from it, to the identification of a biological target. On the example of the synthesis of the first chemical medicaments, the research directions and reasoning of the scientists of that time were indicated. By discussing the history of antimicrobials, the pathway from Fleming's accidental discovery to the organic synthesis of compounds with non-antimicrobial biological activity was outlined. This fact overlaps with the history of the development of anti-cancer drugs, which was discussed in terms of the main mechanisms of action.
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