Published : 2019-08-07

REVIEW OF CURRENT GUIDELINES AND STUDIES ON USE OF ACETYLSALICYLIC ACID IN THE PRIMARY CARDIOVASCULAR EVENTS PREVENTION

Tomasz Kordowski

Tomasz Tatara

Adam Fronczak

Abstract

Acetylsalicylic acid is a medicinal substance common use in medicine. The property of inhibiting platelet aggregation is widely used in the prevention of cardiovascular diseases. The role of acetylsalicylic acid is well established in the prevention of secondary cardiovascular events, while in the primary prevention of cardiovascular events, the opinions of researchers and cardiology association are divided. In the presented studies, acetylsalicylic acid reduced the risk of cardiovascular episodes, however, the risk of bleeding was often greater than the benefits of aspirin in primary prevention. There are many acetylsalicylic acid products available on the market. In order to minimize the risk of local irritation in the gastrointestinal tract, the use of film-coated formulations should be considered. The combination of acetylsalicylic acid and glycine seems promising, which increases the solubility of acetylsalicylic acid and has protective properties.

Keywords:

acetylsalicylic acid, prevention, cardiovascular events, glycine



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Kordowski, T., Tatara, T., & Fronczak, A. (2019). REVIEW OF CURRENT GUIDELINES AND STUDIES ON USE OF ACETYLSALICYLIC ACID IN THE PRIMARY CARDIOVASCULAR EVENTS PREVENTION. Prospects in Pharmaceutical Sciences, 17(4), 20–23. https://doi.org/10.56782/pps.29

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Editorial Team
Stefana Banacha 1
02-097 Warsaw, Poland
biuletynfarmacji@wum.edu.pl
Publisher:
Medical University of Warsaw
ul. Żwirki i Wigury 61
02-091 Warszawa

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