Curbing anti-microbial resistance of synthetic medicinal agents using herbal drug alternatives: current trends and future insights

Rabia Bushra; Farah Saeed; Zuhaib Ahmed; Sabahat Naeem; Javeria Ishaq; Syeda Yusma Saleem

doi:10.56782/pps.341

Published : 2025-05-12

Vol. 23 No. 2 (2025)

Curbing anti-microbial resistance of synthetic medicinal agents using herbal drug alternatives: current trends and future insights

Prof. Rabia Bushra

Dr Farah Saeed

Mr Zuhaib Ahmed

Dr Sabahat Naeem

Ms Javeria Ishaq

Ms Syeda Yusma Saleem

DOI: https://doi.org/10.56782/pps.341

Abstract

Anti-microbial resistance represents a critical global health threat, undermining the effectiveness of conventional antibiotics and posing challenges in the treatment of infectious diseases. The increasing resistance to synthetic anti-microbial agents underscores the urgent need to explore alternative therapeutic approaches, particularly through natural and herbal remedies. Unlike synthetic drugs, which are often associated with harmful side effects and toxicity, medicinal plants offer a promising, safer alternative due to their rich array of bioactive compounds. These plant-derived substances have demonstrated significant anti-microbial activity against a variety of pathogens. Traditionally, medicinal plants have been used to treat a wide range of diseases and conditions, but their potential must be validated and standardized through scientific research to ensure both efficacy and safety. The anti-microbial properties of medicinal plants stem from their diverse phytochemical constituents, including alkaloids, flavonoids, terpenoids, and phenolic compounds, which exhibit broad-spectrum activity against bacteria, fungi, and viruses. This review explores the anti-microbial potential of these plant-based compounds, emphasizing their broad-spectrum efficacy in combating resistant pathogens. It also highlights the importance of further research to optimize the use of medicinal plants in modern healthcare, offering a viable strategy to mitigate the growing threat of anti-microbial resistance and provide safer alternatives to conventional antibiotics.

Keywords:

micro-organism, phytoconstituents, medicinal uses, herbal nanoparticles, in-silico studies

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Bushra, R., Saeed, F., Ahmed, Z., Naeem, S., Ishaq, J., & Saleem, S. Y. (2025). Curbing anti-microbial resistance of synthetic medicinal agents using herbal drug alternatives: current trends and future insights. Prospects in Pharmaceutical Sciences, 23(2), 50–66. https://doi.org/10.56782/pps.341

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