Cotoneaster horizontalis Decne. (Rosaceae) - medicinal or just ornamental species?

Authors

  • Barbara Krzemińska Department of Pharmaceutical Botany, Faculty of Pharmacy, Medical University of Lublin, 20-093 Lublin, Poland.
  • Gabriela Szewczyk Student Scientific Association at the 2nd Department of Obstetrics and Gynecology, Faculty of Medicine, Medical University of Warsaw, 00-315 Warsaw, Poland.

DOI:

https://doi.org/10.56782/pps.187

Keywords:

Cotoneaster, Rosaceae, medicinal plants, ornamental plants

Abstract

The genus Cotoneaster Medikus (Rosaceae) includes many species traditionally used in Asian medicine to treat, among others, cardiovascular diseases, cuts and wounds, diabetes, hemorrhoids, abdominal pain, eye diseases and fever. A representative of this group of plants is Cotoneaster horizontalis Decne., whose health-promoting and healing effects have been confirmed in many scientific studies. To date, compounds such as phenolic acids, flavonoids, cyanogenic glycosides, essential oils, fatty acids, triterpenes, sterols and vitamins have been identified or isolated in the leaves, fruits, flowers and twigs of C. horizontalis. Many of them are responsible for pharmacological properties, including antioxidant, hepatoprotective, antidiabetic, antibacterial and antifungal properties. Despite numerous studies on the phytochemistry, pharmacology and toxicology of extracts from individual parts of C. horizontalis, the available literature lacks a review paper summarizing the achievements of current reports on the effects and safety of use of this species. This work is a collection of information available in the scientific literature regarding the morphology, chemical composition, biological activity and cytotoxicity of extracts and compounds obtained from C. horizontalis. This work, by indicating further research perspectives, constitutes an important reference base for subsequent research on various medical applications of both extracts and pure isolates of C. horizontalis.

Downloads

Download data is not yet available.

References

Ribeiro, A.S.; Estanqueiro, M.; Oliveira, M.B.; Sousa Lobo, J.M. Main benefits and applicability of plant extracts in skin care products. Cosmetics 2015, 2, 48–65. doi:10.3390/cosmetics2020048. DOI: https://doi.org/10.3390/cosmetics2020048

https://www.worldfloraonline.org/taxon/wfo-4000009472 (accessed on 05.02.2024).

Chang, C.-S.; Jeon, J.I. Leaf flavonoids in Cotoneaster wilsonii (Rosaceae) from the island Ulleung-do, Korea. Biochem. Syst. Ecol. 2003, 31, 171–179. doi:10.1016/S0305-1978(02)00064-9. DOI: https://doi.org/10.1016/S0305-1978(02)00064-9

Mahmutović-Dizdarević, I.; Dizdar, M.; Čulum, D.; Vidic, D.; Dahija, S.; Jerković-Mujkić, A.; Bešta-Gajević, R. Phenolic composition, antioxidant and antimicrobial activity of Cotoneaster Medik. species from Bosnia and Herzegovina. Bull. Chem. Technol. Bosnia Herzeg. 2020, 54, 1–6. doi: 10.35666/ghtbh.2020.54.01.

Khan, S.; Wang, Z.;Wang, R.; Zhang, L. Horizontoates A–C: New cholinesterase inhibitors from Cotoneaster horizontalis. Phytochem. Lett. 2014, 10, 204–208. doi: 10.1016/j.phytol.2014.09.007. DOI: https://doi.org/10.1016/j.phytol.2014.09.007

Holzer, V.M.D.; Lower-Nedza, A.D.; Nandintsetseg, M.; Batkhuu, J.; Brantner, A.H. Antioxidant constituents of Cotoneaster melanocarpus Lodd. Antioxidants 2013, 2, 265–272. doi: 10.3390/antiox2040265. DOI: https://doi.org/10.3390/antiox2040265

Les, F.; López, V.; Caprioli, G.; Iannarelli, R.; Fiorini, D.; Innocenti, M.; Bellumori, M.; Maggi, F. Chemical constituents, radical scavenging activity and enzyme inhibitory capacity of fruits from Cotoneaster pannosus Franch. Food Funct. 2017, 8, 1775–1784. doi: 10.1039/C7FO00330G. DOI: https://doi.org/10.1039/C7FO00330G

Zengin, G.; Uysal, A.; Gunes, E.; Aktumsek, A. Survey of phytochemical composition and biological effects of three extracts from a wild plant (Cotoneaster nummularia Fisch. et Mey.): A potential source for functional food ingredients and drug formulations. PLoS ONE. 2014, 9(11), doi: 10.1371/journal.pone.0113527. DOI: https://doi.org/10.1371/journal.pone.0113527

Zengin, G.; Ferrante, C.; Menghini, L.; Orlando, G.; Brunetti, L.; Recinella, L.; Chiavaroli, A.; Leone, S.; Ronci, M.; Aumeeruddy, M.Z.; et al. Protective effects of Cotoneaster integerrimus on in vitro and ex-vivo models of H2O2-induced lactate dehydrogenase activity in HCT116 cell and on lipopolysaccharide-induced inflammation in rat colon. J. Food Biochem. 2019, 43, doi: 10.1111/jfbc.12766. DOI: https://doi.org/10.1111/jfbc.12766

Esmaeili, S.; Ghiaee, A.; Naghibi, F.; Mosaddegh, M. Antiplasmodial activity and cytotoxicity of plants used in traditional medicine of Iran for the treatment of fever. Iran J. Pharm. Res. 2015, 14, 103–107.

Kicel, A.; Kołodziejczyk-Czepas, J.; Owczarek, A.; Marchelak, A.; Sopinska, M.; Ciszewski, P.; Nowak, P.; Olszewska, M.A. Polyphenol-rich extracts from Cotoneaster leaves inhibit pro-inflammatory enzymes and protect human plasma components against oxidative stress in vitro. Molecules 2018, 23, Art. No: 2472. doi: 10.3390/molecules23102472. DOI: https://doi.org/10.3390/molecules23102472

Swati, S.; Manjula, R.R.; Sowjanya, K.; Vennela, Y.; Tanuja, K. A phyto pharmacological review on Cotoneaster microphyllus species. J. Pharm. Sci. Res. 2018, 10, 2166–2168.

Khan, S.; Yasmeen, S.; Afza, N.; Malik, A.; Iqbal, L.; Lateef, M. Cotonoates A and B, new aromatic esters from Cotoneaster racemiflora. Z. Naturforsch. B. 2008, 63, 1219–1222. doi: 10.1515/znb-2008-1013. DOI: https://doi.org/10.1515/znb-2008-1013

https://powo.science.kew.org (accessed on 10.01.2024).

Dickoré, W.B.; Kasperek, G. Species of Cotoneaster (Rosaceae, Maloideae) indigenous to, naturalising or commonly cultivated in Central Europe. Willdenowia 2010, 40, 13-45. doi:10.3372/wi.40.40102. DOI: https://doi.org/10.3372/wi.40.40102

Piqueray, J.; Mahy, G.; Vanderhoeven, S. Naturalization and impact of a horticultural species, Cotoneaster horizontalis (Rosaceae) in biodiversity hotspots in Belgium. Belgian J. Bot. 2008, 141, 113-124. doi:10.2307/20794659.

Jerzak, E. Irgi uprawiane w Polsce, Wyd. 1; Officina Botanica, Kraków, Polska, 2007; p. 31.

Bailey, L.H.; Bailey, E.Z. Hortus Third: A Concise Dictionary of Plants Cultivated in the United States and Canada, Revised by Staff of the L. H. Bailey Hortium; The Macmillan Publishing Company, New York, 1976.

Kicel, A. An overview of the genus Cotoneaster (Rosaceae): phytochemistry, biological activity, and toxicology. Antioxidants 2020, 9, Art. No: 1002. doi: 10.3390/antiox9101002. DOI: https://doi.org/10.3390/antiox9101002

Popoviciu, D.R.; Negreanu-Pirjol, T.; Motelica, L.; Pirjol, B.S.N. Carotenoids, flavonoids, total phenolic compounds and antioxidant activity of two creeping Cotoneaster species fruits extracts. Rev. Chim. 2020, 71, 136-142 doi: 10.37358/RC.20.3.7981. DOI: https://doi.org/10.37358/RC.20.3.7981

Sokkar, N.; El-Gindi, O.; Sayed, S.; Mohamed, S.; Ali, Z.; Alfishawy, I. Antioxidant, anticancer and hepatoprotective activities of Cotoneaster horizontalis Decne extract as well as α-tocopherol and amygdalin production from in vitro culture. Acta Physiol. Plant. 2013, 35, 2421–2428. doi: 10.1007/s11738-013-1276-z. DOI: https://doi.org/10.1007/s11738-013-1276-z

Mohamed, S.A.; Sokkar, N M.; El-Gindi, O.; Ali, Z.Y.; Alfishawy, I.A. Phytoconstituents investigation, anti-diabetic and anti-dyslipidemic activities of Cotoneaster horizontalis Decne cultivated in Egypt. Life Sci. J. 2012, 9, 394-403.

Sytar, O.; Hemmerich, I.; Zivcak, M.; Rauh, C.; Brestic, M. Comparative analysis of bioactive phenolic compounds composition from 26 medicinal plants. Saudi J. Biol. Sci. 2018, 25, 631-641. doi: 10.1016/j.sjbs.2016.01.036. DOI: https://doi.org/10.1016/j.sjbs.2016.01.036

Kicel, A.; Michel, P.; Owczarek, A.; Marchelak, A.; Zyzelewicz, D.; Budryn, G.; Oracz, J.; Olszewska, M.A. Phenolic profile and antioxidant potential of leaves from selected Cotoneaster Medik. species. Molecules 2016, 21, 688. doi: 10.3390/molecules21060688. DOI: https://doi.org/10.3390/molecules21060688

Kicel, A.; Kolodziejczyk-Czepas, J.; Owczarek, A.; Rutkowska, M.; Wajs-Bonikowska, A.; Granica, S.; Nowak, P.; Olszewska, M.A. Multifunctional phytocompounds in Cotoneaster fruits: phytochemical profiling, cellular safety, anti-Inflammatory and antioxidant effects in chemical and human plasma models in vitro. Oxid. Med. Cell Longev. 2018, 24, 3482521. doi: 10.1155/2018/3482521. DOI: https://doi.org/10.1155/2018/3482521

Koss-Mikołajczyk, I.; Baranowska, M.; Namieśnik, J.; Bartoszek-Pączkowska, A. Metody oznaczania właściwości przeciwutleniających fitozwiązków w systemach komórkowych z wykorzystaniem zjawiska fluorescencji/luminescencji. Postępy Hig. Med. Dosw. 2017, 71, 602-616; doi: 10.5604/01.3001.0010.3841. DOI: https://doi.org/10.5604/01.3001.0010.3841

Krzemińska, B.; Dybowski, M.P.; Klimek, K.; Typek, R.; Miazga-Karska, M.; Dos Santos Szewczyk, K. The anti-acne potential and chemical composition of two cultivated Cotoneaster species. Cells 2022, 11, Art. No: 367. doi.org/10.3390/cells11030367. DOI: https://doi.org/10.3390/cells11030367

Downloads

Published

2024-05-16

Issue

Section

Articles

How to Cite

Cotoneaster horizontalis Decne. (Rosaceae) - medicinal or just ornamental species?. (2024). Prospects in Pharmaceutical Sciences, 22(2), 50-58. https://doi.org/10.56782/pps.187

Similar Articles

1-10 of 69

You may also start an advanced similarity search for this article.