Autism: plants with neuro-psychopharmacotherapeutic potential
DOI:
https://doi.org/10.56782/pps.143Keywords:
autism, medicinal plants, pharmacotherapeutic, complementary medicineAbstract
In recent years, there has been an increasing prevalence of cases of autism. There is no general cure for autism; however, there are situational treatments available. In this context, plants may be beneficial in suppressing the conditions that may arise in the disease. This study compiles plant species that have been reported in the literature as potential remedies for autism disorders. Furthermore, the general characteristics, usage areas, and biological activities of these plant species have been compiled. As a result of our research, it has been seen that plants can be used to combat many symptoms of autism. It is believed that plants may contribute to the improvement of the well-being of individuals with autism, as a result.
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Krupodorova, T.; Sevindik, M. Antioxidant potential and some mineral contents of wild edible mushroom Ramaria stricta. AgroLife Sci. J., 2020, 9(1), 186-191.
Sevindik, M. Antioxidant and antimicrobial capacity of Lactifluus rugatus and its antiproliferative activity on A549 cells. Indian J. Tradit. Know, 2020, 19(2), 423-427. https://doi.org/10.56042/ijtk.v19i2.35356 DOI: https://doi.org/10.56042/ijtk.v19i2.35356
Selamoglu, Z.; Sevindik, M.; Bal, C.; Ozaltun, B.; Sen, İ.; Pasdaran, A. Antioxidant, antimicrobial and DNA protection activities of phenolic content of Tricholoma virgatum (Fr.) P. Kumm. Biointerface Res. Appl. Chem, 2020, 10(3), 5500-5506. https://doi.org/10.33263/BRIAC103.500506 DOI: https://doi.org/10.33263/BRIAC103.500506
Eraslan, E. C.; Altuntas, D.; Baba, H.; Bal, C.; Akgül, H.; Akata, I.; Sevindik, M. Some biological activities and element contents of ethanol extract of wild edible mushroom Morchella esculenta. Sigma J. Engin. Nat. Sci., 2021, 39(1), 24-28.
Sevindik, M. Anticancer, antimicrobial, antioxidant and DNA protective potential of mushroom Leucopaxillus gentianeus (Quél.) Kotl. Indian J. Exp. Biol., 2021, 59(05), 310-315. https://doi.org/ 10.56042/ijeb.v59i05.50501
Bal, C.; Sevindik, M.; Akgul, H.; Selamoglu, Z. Oxidative stress index and antioxidant capacity of Lepista nuda collected from Gaziantep/Turkey. Sigma J. Engin. Nat. Sci., 2019, 37(1), 1-5. DOI: https://doi.org/10.1155/2020/5620484
Sevindik, M.; Akgul, H.; Pehlivan, M.; Selamoglu, Z. Determination of therapeutic potential of Mentha longifolia ssp. longifolia. Fresenius Environ. Bull., 2017, 26(7), 4757-4763.
Mohammed, F. S.; Günal, S.; Şabik, A. E.; Akgül, H.; Sevindik, M. Antioxidant and Antimicrobial activity of Scorzonera papposa collected from Iraq and Turkey. KSU J. Agric. Nat., 2020, 23(5), 1114-1118. https://doi.org/ 10.18016/ksutarimdoga.vi.699457 DOI: https://doi.org/10.18016/ksutarimdoga.vi.699457
Korkmaz, N.; Dayangaç, A.; Sevindik, M. Antioxidant, antimicrobial and antiproliferative activities of Galium aparine. J. Fac. Pharm. Ankara, 2021, 45(3), 554-564. https://doi.org/10.33483/jfpau.977776 DOI: https://doi.org/10.33483/jfpau.977776
Żero, P.; Niemyjska, M.; Rasztawicka, M.; Maciejewska, D. Choroba Nowotworowa Pıersı I Nowe Zwıązkı O Aktywnoścı Przecıwnowotworowej. Prospects Pharm. Sci., 2005, 3(2), 10-18. https://doi.org/10.56782/pps.53 DOI: https://doi.org/10.56782/pps.53
Kawka, M.; Pilarek, M.; Sykłowska-Baranek, K.; Pietrosiuk, A. Ekstrakcja In Sıtu Roślınnych Metabolıtów Wtórnych. Prospects Pharm. Sci., 2017, 15(7), 60-67. https://doi.org/10.56782/pps.78 DOI: https://doi.org/10.56782/pps.78
Mohammed, F. S.; Akgul, H.; Sevindik, M.; Khaled, B. M. T. Phenolic content and biological activities of Rhus coriaria var. zebaria. Fresenius Environ. Bull., 2018, 27(8), 5694-5702.
Mohammed, F. S.; Karakaş, M.; Akgül, H.; Sevindik, M. Medicinal properties of Allium calocephalum collected from Gara Mountain (Iraq). Fresenius Environ. Bull., 2019, 28(10), 7419-7426.
Mohammed, F. S.; Pehlivan, M.; Sevindik, E.; Akgul, H.; Sevindik, M.; Bozgeyik, I.; Yumrutas, O. Pharmacological properties of edible Asparagus acutifolius and Asparagus officinalis collected from North Iraq and Turkey (Hatay). Acta Aliment., 2021, 50(1), 136-143. https://doi.org/10.1556/066.2020.00204 DOI: https://doi.org/10.1556/066.2020.00204
Unal, O.; Eraslan, E. C.; Uysal, I.; Mohammed, F. S.; Sevindik, M.; Akgul, H. Biological activities and phenolic contents of Rumex scutatus collected from Turkey. Fresenius Environ. Bull., 2022, 31(7), 7341-7346.
Mohammed, F. S.; Uysal, I.; Sevindik, M. Functional food Momordica charantia: biological activities. Prospects Pharm. Sci., 2023, 21(3), 22-29. https://doi.org/10.56782/pps.138 DOI: https://doi.org/10.56782/pps.138
Mohammed, F. S.; Kına, E.; Sevindik, M.; Doğan, M.; Pehlivan, M. Antioxidant and antimicrobial activities of ethanol extract of Helianthemum salicifolium (Cistaceae). Indian J. Nat. Prod. Resour., 2021, 12(3), 459-462. https://doi.org/ 10.56042/ijnpr.v12i3.46635
Mohammed, F. S.; Günal, S.; Pehlivan, M.; Doğan, M.; Sevindik, M.; Akgül, H. Phenolic content, antioxidant and antimicrobial potential of endemic Ferulago platycarpa. Gazi Univ. J. Sci., 2020, 33(4), 670-677. https://doi.org/10.35378/gujs.707555 DOI: https://doi.org/10.35378/gujs.707555
Mohammed, F. S.; Uysal, I.; Sevindik, M. A review on antiviral plants effective against different virus types. Prospects Pharm. Sci., 2023, 21(2), 1-21. https://doi.org/10.56782/pps.128 DOI: https://doi.org/10.56782/pps.128
Johnson, C. P.; Myers, S. M. Identification and evaluation of children with autism spectrum disorders. Pediatrics, 2007, 120(5), 1183-1215. https://doi.org/10.1542/peds.2007-2361 DOI: https://doi.org/10.1542/peds.2007-2361
Frith, U.; Mira, M. Autism and Asperger syndrome. Focus on Autistic Behavior, 1992, 7(3), 13-15. https://doi.org/10.1177/108835769200700302 DOI: https://doi.org/10.1177/108835769200700302
Maenner, M. J.; Shaw, K. A.; Baio, J.; Washington, A.; Patrick, M.; DiRienzo, M.; Christensen, D.L.; Wiggins, L.D.; Pettygrove, S.; Andrews, J.G.; Lopez, M.,; Hudson, A.; Baroud, T.; Schwenk, Y.; White, T.; Rosenberg, C.R.; Lee, L.C.; Harrington, R.A.; Huston, M.; Hewitt, A.; Esler, A.; Hall-Lande, J.; Poynter, J.N.; Hallas-Muchow, L.; Constantino, J.N.; Fitzgerald, R.T.; Zahorodny, W.; Shenouda, J.; Daniels, J.L.; Warren, Z.; Vehorn, A.; Salinas, A.; Durkin, M.S.; Dietz, M.P. Prevalence of autism spectrum disorder among children aged 8 years—autism and developmental disabilities monitoring network, 11 sites, United States, 2016. MMWR Surveill Summ, 2020, 69(4), 1-12. https://doi.org/10.15585/mmwr.ss6904a1 DOI: https://doi.org/10.15585/mmwr.ss6904a1
Won, H.; Mah, W.; Kim, E. Autism spectrum disorder causes, mechanisms, and treatments: focus on neuronal synapses. Front. Mol. Neurosci., 2013, 6, 19. https://doi.org/10.3389/fnmol.2013.00019 DOI: https://doi.org/10.3389/fnmol.2013.00019
Muhle, R.; Trentacoste, S. V.; Rapin, I. The genetics of autism. Pediatrics, 2004, 113(5), e472-e486. https://doi.org/10.1542/peds.113.5.e472 DOI: https://doi.org/10.1542/peds.113.5.e472
Baron‐Cohen, S. Autism: the empathizing–systemizing (E‐S) theory. Ann. N. Y. Acad. Sci., 2009, 1156(1), 68-80. DOI: https://doi.org/10.1111/j.1749-6632.2009.04467.x
Kemper, T. L.; Bauman, M. L. The contribution of neuropathologic studies to the understanding of autism. Neurol. Clin., 1993, 11(1), 175-187. https://doi.org/10.1016/S0733-8619(18)30176-2 DOI: https://doi.org/10.1016/S0733-8619(18)30176-2
Rogers, S. J.; Vismara, L. A. Evidence-based comprehensive treatments for early autism. J. Clin. Child Adolesc., 2008, 37(1), 8-38. https://doi.org/10.1080/15374410701817808 DOI: https://doi.org/10.1080/15374410701817808
Brentani, H.; Paula, C. S. D.; Bordini, D.; Rolim, D.; Sato, F.; Portolese, J.; McCracken, J. T. Autism spectrum disorders: an overview on diagnosis and treatment. Rev. Bras. de Psiquiatr., 2013, 35, S62-S72. https://doi.org/10.1590/1516-4446-2013-S104 DOI: https://doi.org/10.1590/1516-4446-2013-S104
Van Bourgondien, M. E.; Reichle, N. C.; Schopler, E. Effects of a model treatment approach on adults with autism. J. Autism Dev. Disord., 2003, 33, 131-140. DOI: https://doi.org/10.1023/A:1022931224934
Ernst, E.; Pittler, M. H. Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials. Br. J. Anaesth., 2000, 84(3), 367-371. https://doi.org/10.1093/oxfordjournals.bja.a013442 DOI: https://doi.org/10.1093/oxfordjournals.bja.a013442
Gupta, Y. K.; Sharma, M. Reversal of pyrogallol-induced delay in gastric emptying in rats by ginger (Zingiber officinale). Methods Find. Exp. Clin. Pharmacol., 2001, 23(9), 501-503. https://doi.org/ 10.1358/mf.2001.23.9.662137 DOI: https://doi.org/10.1358/mf.2001.23.9.662137
Parashar, A.; Udayabanu, M. Gut microbiota regulates key modulators of social behavior. Eur. Neuropsychopharmacol., 2016, 26(1), 78-91. https://doi.org/10.1016/j.euroneuro.2015.11.002 DOI: https://doi.org/10.1016/j.euroneuro.2015.11.002
Rezapour, S.; Bahmani, M.; Afsordeh, O.; Rafieian, R.; Sheikhian, A. Herbal medicines: a new hope for autism therapy. J. Herbmed Pharma., 2016, 5(3), 89-91.
Kardani, A.; Soltani, A.; Sewell, R. D.; Shahrani, M.; Rafieian-Kopaei, M. Neurotransmitter, antioxidant and anti-neuroinflammatory mechanistic potentials of herbal medicines in ameliorating autism spectrum disorder. Curr. Pharm. Des., 2019, 25(41), 4421-4429. https://doi.org/10.2174/1381612825666191112143940 DOI: https://doi.org/10.2174/1381612825666191112143940
Chilambath, M.; Sundararaman, G. Herbal Remedies for Autism. In Role of Nutrients in Neurological Disorders (pp. 333-347). 2022, Singapore: Springer Singapore. DOI: https://doi.org/10.1007/978-981-16-8158-5_18
Amin, M.; Khikmawati, N. H.; Suryadi, Amin, I. F.; Yayoi, K..; Wibowo, A. H.; Rachman, I. Chemical interaction analysis of L-Theanine compounds from Camellia sinensis L. with kainate glutamate receptors and their toxicity effect as anti-autism candidates based on in silico. In AIP Conference Proceedings (Vol. 2237, No. 1, p. 020072). 2020, AIP Publishing LLC. DOI: https://doi.org/10.1063/5.0008500
Bhandari, R.; Kuhad, A. Neuropsychopharmacotherapeutic efficacy of curcumin in experimental paradigm of autism spectrum disorders. Life Sci., 2015, 141, 156-169. https://doi.org/10.1016/j.lfs.2015.09.012 DOI: https://doi.org/10.1016/j.lfs.2015.09.012
Bhat, A.; Mahalakshmi, A. M.; Ray, B.; Tuladhar, S.; Hediyal, T. A.; Manthiannem, E.; Sakharkar, M. K.. Benefits of curcumin in brain disorders. BioFactors, 2019, 45(5), 666-689. https://doi.org/10.1002/biof.1533 DOI: https://doi.org/10.1002/biof.1533
Deb, S.; Phukan, B. C.; Dutta, A.; Paul, R.; Bhattacharya, P.; Manivasagam, T.; Borah, A. Natural products and their therapeutic effect on autism spectrum disorder. Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management, 2020, 601-614. DOI: https://doi.org/10.1007/978-3-030-30402-7_22
Lopresti, A. L. Curcumin for neuropsychiatric disorders: a review of in vitro, animal and human studies. J. Psychopharmacol., 2017, 31(3), 287-302. https://doi.org/10.1177/0269881116686883 DOI: https://doi.org/10.1177/0269881116686883
Muralidharan, P.; Anamika, P.K. Preclinical Investigation On The Protective Effect Of Bacopa Monnieri On Human Neuroblastoma Cell Line SH-SY5Y On Its Progressive Development And Finding On Autism Spectrum Disorder. J. Pharm. Negat., 2022, 2262-2269. https://doi.org/10.47750/pnr.2022.13.S09.270
Sandhya, T.; Sowjanya, J.; Veeresh, B. Bacopa monniera (L.) Wettst ameliorates behavioral alterations and oxidative markers in sodium valproate induced autism in rats. Neurochem. Res., 2012, 37, 1121-1131. DOI: https://doi.org/10.1007/s11064-012-0717-1
Urdaneta, K. E.; Castillo, M. A.; Montiel, N.; Semprún-Hernández, N.; Antonucci, N.; Siniscalco, D. Autism spectrum disorders: potential neuro-psychopharmacotherapeutic plant-based drugs. Assay Drug Dev. Technol., 2018, 16(8), 433-444. https://doi.org/10.1089/adt.2018.848 DOI: https://doi.org/10.1089/adt.2018.848
Ahmed, A. A.; Eltahan, N. R.; Elsherif, S. A.; Elsaadany, M. Therapeutic Effect of Selected Plants on Autistic Rats. J. Home Econ., 2018, 28.
Hadland, S. E.; Knight, J. R.; Harris, S. K. Medical marijuana: Review of the science and implications for developmental behavioral pediatric practice. J. Dev. Behav. Pediatr., 2015, 36(2), 115-123. https://doi.org/ 10.1097/DBP.0000000000000129 DOI: https://doi.org/10.1097/DBP.0000000000000129
Niederhofer, H. First preliminary results of an observation of Ginkgo Biloba treating patients with autistic disorder. Phyto. Res., 2009, 23(11), 1645-1646. https://doi.org/10.1002/ptr.2778 DOI: https://doi.org/10.1002/ptr.2778
Román, G. C. Autism: transient in utero hypothyroxinemia related to maternal flavonoid ingestion during pregnancy and to other environmental antithyroid agents. J. Neurol. Sci., 2007, 262(1-2), 15-26. https://doi.org/10.1016/j.jns.2007.06.023 DOI: https://doi.org/10.1016/j.jns.2007.06.023
Woolf, A. D. Herbal remedies and children: do they work? Are they harmful?. Pediatrics, 2003, 112(1-2), 240-246. DOI: https://doi.org/10.1542/peds.112.S1.240
Agarwal, R., Burke, S. L., Maddux, M. (2019). Current state of evidence of cannabis utilization for treatment of autism spectrum disorders. BMC psychiatry, 2003, 19(1), 1-10. DOI: https://doi.org/10.1186/s12888-019-2259-4
Aran, A.; Cassuto, H.; Lubotzky, A.; Wattad, N.; Hazan, E. Brief report: cannabidiol-rich cannabis in children with autism spectrum disorder and severe behavioral problems—a retrospective feasibility study. J. Autism Dev. Disord., 2019, 49(3), 1284-1288. DOI: https://doi.org/10.1007/s10803-018-3808-2
Mostafavi, M.; Gaitanis, J.. Autism spectrum disorder and medical cannabis: review and clinical experience. In Seminars in pediatric neurology (Vol. 35, p. 100833). 2020, WB Saunders. DOI: https://doi.org/10.1016/j.spen.2020.100833
Perucca, E.. Cannabinoids in the treatment of epilepsy: hard evidence at last?. J. Epilepsy Res., 2017, 7(2), 61. https://doi.org/ 10.14581/jer.17012 DOI: https://doi.org/10.14581/jer.17012
Solimini, R.; Rotolo, M. C.; Pichini, S.; Pacifici, R. Neurological disorders in medical use of cannabis: an update. CNS Neurol. Disord. Drug. Targets, 2017, 16(5), 527-533. https://doi.org/10.2174/1871527316666170413105421 DOI: https://doi.org/10.2174/1871527316666170413105421
Babayeva, M.; Assefa, H.; Basu, P.; Loewy, Z. Autism and associated disorders: cannabis as a potential therapy. Frontiers in Bioscience-Elite, 2022, 14(1), 1. https://doi.org/ 10.31083/j.fbe1401001 DOI: https://doi.org/10.31083/j.fbe1401001
Bedir, E.; Pugh, N.; Calis, I.; Pasco, D. S.; Khan, I. A. Immunostimulatory effects of cycloartane-type triterpene glycosides from Astragalus species. Biol. Pharma. Bull., 2000, 23(7), 834-837. https://doi.org/10.1248/bpb.23.834 DOI: https://doi.org/10.1248/bpb.23.834
Guenné, S.; Ouedraogo, G. G.; Lefter, R.; Timofte, D.; Foyet, H. S.; Hilou, A.; Kiendrebéogo, M. Anxiolytic and anti-depressant effect of Salvia spp. essential oil on rat model of Autism Spectrum Disorder. Bull. Integ. Psych., 2020, 84(1), 19-28. DOI: https://doi.org/10.36219/BPI.2020.1.02
Schnapp, A.; Harel, M.; Cayam-Rand, D.; Cassuto, H.; Polyansky, L.; Aran, A. A Placebo-Controlled Trial of Cannabinoid Treatment for Disruptive Behavior in Children and Adolescents with Autism Spectrum Disorder: Effects on Sleep Parameters as Measured by the CSHQ. Biomedicines, 2022, 10(7), 1685. https://doi.org/10.3390/biomedicines10071685 DOI: https://doi.org/10.3390/biomedicines10071685
Zheng, Z.; Liu, D.; Song, C.; Cheng, C.; Hu, Z. Studies on chemical constituents and immunological function activity of hairy root of Astragalus membranaceus. Chinese j. biotech., 1998, 14(2), 93-97.
Amini, F.; Amini-Khoei, H.; Haratizadeh, S.; Setayesh, M.; Basiri, M.; Raeiszadeh, M.; Nozari, M. Hydroalcoholic extract of Passiflora incarnata improves the autistic-like behavior and neuronal damage in a valproic acid-induced rat model of autism. J. Tradit. Complement. Med., 2023, https://doi.org/10.1016/j.jtcme.2023.02.005. DOI: https://doi.org/10.1016/j.jtcme.2023.02.005
El-Ansary, A.; Ibrahim, E. M.; Shafi Bhat, R.. Lepidium sativum seeds as a suggested complex nutritional supplement to treat biomarkers related deficits in autism. Nov. Tech. Nutr. Food Sci., 2019, 3(3), 258-62. DOI: https://doi.org/10.31031/NTNF.2019.03.000562
Joon, P.; Dhingra, D.; Parle, M. Biochemical evidence for anti-autistic potential of Asparagus racemosus. Int. J. Plant Sci., 2020, 15(1), 42-51. DOI: https://doi.org/10.15740/HAS/IJPS/15.1/42-51
Nessma, E.; Metwally, M. A.; Samah, H. Assessment of Oil and Seed Extracts of Moringa oleifera for Promising Anticandidal Activity in Autistic Children. Egyptian J. Bot., 2022, 62(3), 825-835. https://doi.org/ 10.21608/ejbo.2022.61779.1624
Dhanik, J.; Arya, N.; Nand, V. A review on Zingiber officinale. J. pharmacogn. phytochem., 2017, 6(3), 174-184.
Ujang, Z.; Nordin, N. I.; Subramaniam, T. Ginger species and their traditional uses in modern applications. J. Ind. Technol. 2015, 23(1), 59-70. DOI: https://doi.org/10.21908/jit.2015.4
Kumar Gupta, S.; Sharma, A. Medicinal properties of Zingiber officinale Roscoe-A review. J. Pharm. Biol. Sci, 2014, 9, 124-129. DOI: https://doi.org/10.9790/3008-0955124129
Loying, R.; Gogoi, R.; Sarma, N.; Borah, A.; Munda, S.; Pandey, S. K.; Lal, M. Chemical compositions, in-vitro antioxidant, anti-microbial, anti-inflammatory and cytotoxic activities of essential oil of Acorus calamus L. rhizome from North-East India. J. Essent. Oil-Bear. Plants, 2019, 22(5), 1299-1312. DOI: https://doi.org/10.1080/0972060X.2019.1696236
Rajput, S. B.; Tonge, M. B.; Karuppayil, S. M. An overview on traditional uses and pharmacological profile of Acorus calamus Linn.(Sweet flag) and other Acorus species. Phytomedicine, 2014, 21(3), 268-276. https://doi.org/10.1016/j.phymed.2013.09.020 DOI: https://doi.org/10.1016/j.phymed.2013.09.020
Balakumbahan, R.; Rajamani, K.; Kumanan, K. Acorus calamus: An overview. J. Med. Plants Res., 2010, 4(25), 2740-2745.
Singh, R.; Sharma, P. K.; Malviya, R. Pharmacological properties and ayurvedic value of Indian buch plant (Acorus calamus): a short review. Adv. Biol. Res., 2011, 5(3), 145-154.
Pachiappan, S.; Matheswaran, S.; Saravanan, P. P.; Muthusamy, G. Medicinal plants for polycystic ovary syndrome: A review of phytomedicine research. Int. J. Herb. Med., 2017, 5(2), 78-80.
Salari, S.; Amiri, M. S.; Ramezani, M.; Moghadam, A. T.; Elyasi, S.; Sahebkar, A.; Emami, S. A. Ethnobotany, phytochemistry, traditional and modern uses of Actaea racemosa L.(Black cohosh): a review. Pharmacological Properties of Plant-Derived Natural Products and Implications for Human Health, 2021, 403-449. DOI: https://doi.org/10.1007/978-3-030-64872-5_24
Nuntanakorn, P.; Jiang, B.; Einbond, L. S.; Yang, H.; Kronenberg, F.; Weinstein, I. B.; Kennelly, E. J. Polyphenolic Constituents of Actaea racemosa. J. Nat. Prod., 2006, 69(3), 314-318. DOI: https://doi.org/10.1021/np0501031
Kursinszki, L. Factors influencing the pharmaceutically important characteristics of Lobelia inflata L. Afr. J. Tradit. Complement. Altern. Med., 2009, 318-318.
Folquitto, D. G.; Swiech, J. N.; Pereira, C. B.; Bobek, V. B.; Possagno, G. C. H.; Farago, P. V.; Miguel, O. G. Biological activity, phytochemistry and traditional uses of genus Lobelia (Campanulaceae): A systematic review. Fitoterapia, 2019, 134, 23-38. https://doi.org/10.1016/j.fitote.2018.12.021 DOI: https://doi.org/10.1016/j.fitote.2018.12.021
Máthé, Á. Indian Tobacco (Lobelia inflata L.). Medicinal and Aromatic Plants of North America, 2020, 159-186. DOI: https://doi.org/10.1007/978-3-030-44930-8_7
Subarnas, A.; Tadano, T.; Nakahata, N.; Arai, Y.; Kinemuchi, H.; Oshima, Y.; Ohizumi, Y. A possible mechanism of antidepresant activity of beta-amyrin palmitate isolated from lobelia inflata leaves in the forced swimming test. Life Sci., 1993, 52(3), 289-296. DOI: https://doi.org/10.1016/0024-3205(93)90220-W
He, D. Y.; Dai, S. M. Anti-inflammatory and immunomodulatory effects of Paeonia lactiflora Pall., a traditional Chinese herbal medicine. Frontiers pharmacol., 2011, 2, 10. https://doi.org/10.3389/fphar.2011.00010 DOI: https://doi.org/10.3389/fphar.2011.00010
Parker, S.; May, B.; Zhang, C.; Zhang, A. L.; Lu, C.; Xue, C. C. A pharmacological review of bioactive constituents of Paeonia lactiflora Pallas and Paeonia veitchii Lynch. Phyto. Res., 2016, 30(9), 1445-1473. https://doi.org/10.1002/ptr.5653
Zhao, D. D.; Jiang, L. L.; Li, H. Y.; Yan, P. F.; Zhang, Y. L. Chemical components and pharmacological activities of terpene natural products from the genus Paeonia. Molecules, 2016, 21(10), 1362. https://doi.org/10.3390/molecules21101362 DOI: https://doi.org/10.3390/molecules21101362
Parker, S.; May, B.; Zhang, C.; Zhang, A. L.; Lu, C.; Xue, C. C. A pharmacological review of bioactive constituents of Paeonia lactiflora Pallas and Paeonia veitchii Lynch. Phyto. Res., 2016, 30(9), 1445-1473. https://doi.org/10.1002/ptr.5653 DOI: https://doi.org/10.1002/ptr.5653
Ferrara, L.; Montesano, D.; Senatore, A. The distribution of minerals and flavonoids in the tea plant (Camellia sinensis). Il farmaco, 2001, 56(5-7), 397-401. https://doi.org/10.1016/S0014-827X(01)01104-1 DOI: https://doi.org/10.1016/S0014-827X(01)01104-1
Sharangi, A. B. Medicinal and therapeutic potentialities of tea (Camellia sinensis L.)–A review. Food Res. Int., 2009, 42(5-6), 529-535. https://doi.org/10.1016/j.foodres.2009.01.007 DOI: https://doi.org/10.1016/j.foodres.2009.01.007
Namita, P.; Mukesh, R.; Vijay, K. J. Camellia sinensis (green tea): a review. Glob. J. Pharmacol., 2012, 6(2), 52-59.
Zhang, L.; Ho, C. T.; Zhou, J.; Santos, J. S.; Armstrong, L.; Granato, D. Chemistry and biological activities of processed Camellia sinensis teas: A comprehensive review. Compr. Rev. Food Sci. Food Saf., 2019, 18(5), 1474-1495. DOI: https://doi.org/10.1111/1541-4337.12479
Thangaselvabal, T.; Gailce Leo Justin, C.; Leelamathi, M. Black pepper (Piper nigrum L.)‘the king of spices’–A review. Agri. Rev., 2008, 29(2), 89-98.
Meghwal, M.; Goswami, T. K. Piper nigrum and piperine: an update. Phyto. Res., 2013, 27(8), 1121-1130. DOI: https://doi.org/10.1002/ptr.4972
Damanhouri, Z. A.; Ahmad, A. A review on therapeutic potential of Piper nigrum L. Black Pepper): The King of Spices. Med. Aromat. Plants, 2014, 3(3), 161. http://dx.doi.org/10.4172/2167-0412.1000161 DOI: https://doi.org/10.4172/2167-0412.1000161
Ashokkumar, K.; Murugan, M.; Dhanya, M. K.; Pandian, A.; Warkentin, T. D. Phytochemistry and therapeutic potential of black pepper [Piper nigrum (L.)] essential oil and piperine: A review. Clin. Phytosci., 2021, 7(1), 1-11. DOI: https://doi.org/10.1186/s40816-021-00292-2
Akram, M.; Shahab-Uddin, A. A.; Usmanghani, K. H. A. N.; Hannan, A. B. D. U. L.; Mohiuddin, E.; Asif, M. Curcuma longa and curcumin: a review article. Rom. J. Biol. Plant. Biol., 2010, 55(2), 65-70.
Krup, V.; Prakash, L. H.; Harini, A. Pharmacological activities of turmeric (Curcuma longa Linn): a review. J. Homeop. Ayurv. Med., 2013, 2(133), 2167-1206. DOI: https://doi.org/10.4172/2167-1206.1000133
Labban, L. Medicinal and pharmacological properties of Turmeric (Curcuma longa): A review. Int. J. Pharm. Biomed. Sci., 2014, 5(1), 17-23.
Tripathi, N.; Chouhan, D. S.; Saini, N.; Tiwari, S. Assessment of genetic variations among highly endangered medicinal plant Bacopa monnieri (L.) from Central India using RAPD and ISSR analysis. 3 Biotech, 2012, 2, 327-336. DOI: https://doi.org/10.1007/s13205-012-0059-3
Sudhakaran, M. V. Botanical Pharmacognosy of Bacopa monnieri (Linn.) Pennell. Pharmacogn. J., 2020, 12(6), 1559-1572. DOI: https://doi.org/10.5530/pj.2020.12.214
Jain, P. K.; Das, D.; Jain, P.; Jain, P. Pharmacognostic and pharmacological aspect of Bacopa monnieri: a review. Int. J. Pharm. Pharm. Sci., 2016, 4(3), 7-11.
Vishnupriya, P.; Padma, V. V. A review on the antioxidant and therapeutic potential of Bacopa monnieri. React. Oxygen Spec., 2017, 3, 111-120. DOI: https://doi.org/10.20455/ros.2017.817
Brar, G. S.; Carter Jr, T. E. Soybean: Glycine max (L) Merrill. Genetic improvement of vegetable crops, 1993, 427-463. DOI: https://doi.org/10.1016/B978-0-08-040826-2.50034-5
Stupar, R. M.; Specht, J. E. Insights from the soybean (Glycine max and Glycine soja) genome: past, present, and future. Adv. Agron., 2013, 118, 177-204. https://doi.org/10.1016/B978-0-12-405942-9.00004-9 DOI: https://doi.org/10.1016/B978-0-12-405942-9.00004-9
Ponnusha, B. S.; Subramaniyam, S.; Pasupathi, P. Antioxidant and Antimicrobial properties of Glycine max-A review. Int. J. Cur. Bio. Med. Sci., 2011, 1(2), 49-62.
Fischer, E.; Cachon, R.; Cayot, N. Pisum sativum vs Glycine max, a comparative review of nutritional, physicochemical, and sensory properties for food uses. Trends Food Sci. Tech., 2020, 95, 196-204. https://doi.org/10.1016/j.tifs.2019.11.021 DOI: https://doi.org/10.1016/j.tifs.2019.11.021
Mahadevan, S.; Park, Y. Multifaceted therapeutic benefits of Ginkgo biloba L.: chemistry, efficacy, safety, and uses. Journal of food science, 2008, 73(1), 14-19. https://doi.org/10.1111/j.1750-3841.2007.00597.x DOI: https://doi.org/10.1111/j.1750-3841.2007.00597.x
Fang, J.; Wang, Z.; Wang, P.; Wang, M. Extraction, structure and bioactivities of the polysaccharides from Ginkgo biloba: A review. Int. J. Biol. Macromol., 2020, 162, 1897-1905. https://doi.org/10.1016/j.ijbiomac.2020.08.141 DOI: https://doi.org/10.1016/j.ijbiomac.2020.08.141
Yoshikawa, T.; Naito, Y.; Kondo, M. Ginkgo biloba leaf extract: review of biological actions and clinical applications. Antioxid. Redox. Signal., 1999, 1(4), 469-480. https://doi.org/10.1089/ars.1999.1.4-469 DOI: https://doi.org/10.1089/ars.1999.1.4-469
Ude, C.; Schubert-Zsilavecz, M.; Wurglics, M. Ginkgo biloba extracts: a review of the pharmacokinetics of the active ingredients. Clin. Pharmacokinet., 2013, 52, 727-749. DOI: https://doi.org/10.1007/s40262-013-0074-5
Clarke, R. C.; Watson, D. P. Botany of natural Cannabis medicines. Cannabis and cannabinoids: pharmacology, toxicology and therapeutic potential, 2002, 3-13.
Rajput, R.; Kumar, K. A review on Cannabis sativa: its compounds and their effects. Int. J. Pharm. Sci. Rev. Res., 2018, 53(2), 59-63.
Manosroi, A.; Chankhampan, C.; Kietthanakorn, B. O.; Ruksiriwanich, W.; Chaikul, P.; Boonpisuttinant, K.; Manosroi, J. Pharmaceutical and cosmeceutical biological activities of hemp (Cannabis sativa L. var. sativa) leaf and seed extracts. Chiang Mai J. Sci, 2019, 46, 180-195.
Ashton, C. H. Pharmacology and effects of cannabis: a brief review. BJPsych, 2001, 178(2), 101-106. DOI: https://doi.org/10.1192/bjp.178.2.101
Asadi, S.; Moghadam, H.; Naghdi Badi, H.; Naghavi, M. R.; Salami, S. A. R. A review on agronomic, phytochemical and pharmacological aspects of cannabis (Cannabis sativa L.). J. Med. Plants, 2019, 18(70), 1-20. DOI: https://doi.org/10.29252/jmp.2.70.1
Fu, J.; Wang, Z.; Huang, L.; Zheng, S.; Wang, D.; Chen, S.; Yang, S. Review of the botanical characteristics, phytochemistry, and pharmacology of Astragalus membranaceus (Huangqi). Phytother. Res, 2014, 28(9), 1275-1283. https://doi.org/10.1002/ptr.5188 DOI: https://doi.org/10.1002/ptr.5188
Zhang, J.; Wu, C.; Gao, L.; Du, G., Qin, X. Astragaloside IV derived from Astragalus membranaceus: A research review on the pharmacological effects. Adv. Pharma., 2020, 87, 89-112. https://doi.org/10.1016/bs.apha.2019.08.002 DOI: https://doi.org/10.1016/bs.apha.2019.08.002
Jin, M.; Zhao, K.; Huang, Q.; Shang, P. Structural features and biological activities of the polysaccharides from Astragalus membranaceus. Int. J. Biol. Macromol., 2014, 64, 257-266. DOI: https://doi.org/10.1016/j.ijbiomac.2013.12.002
Gohil, K. J.; Patel, J. A.; Gajjar, A. K.. Pharmacological review on Centella asiatica: a potential herbal cure-all. Indian J. Pharm. Sci., 2010, 72(5), 546. DOI: https://doi.org/10.4103/0250-474X.78519
Pittella, F.; Dutra, R. C.; Junior, D. D.; Lopes, M. T.; Barbosa, N. R. Antioxidant and cytotoxic activities of Centella asiatica (L) Urb. Int. J. Mol. Sci., 2009, 10(9), 3713-3721. DOI: https://doi.org/10.3390/ijms10093713
Torbati, F. A.; Ramezani, M.; Dehghan, R.; Amiri, M. S.; Moghadam, A. T.; Shakour, N.; Emami, S. A. Ethnobotany, phytochemistry and pharmacological features of Centella asiatica: a comprehensive review. Pharmacological Properties of Plant-Derived Natural Products and Implications for Human Health, 2021, 451-499. DOI: https://doi.org/10.1007/978-3-030-64872-5_25
Pehlivan, M.; Sevindik, M. Antioxidant and antimicrobial activities of Salvia multicaulis. Turkish JAF Sci.Tech., 2018, 6(5), 628-631. DOI: https://doi.org/10.24925/turjaf.v6i5.628-631.1906
Uysal, I.; Koçer, O.; Mohammed, F. S.; Lekesiz, Ö.; Doğan, M.; Şabik, A. E.; Sevindik, E.; Gerçeker, F.Ö.; Sevindik, M. Pharmacological and Nutritional Properties: Genus Salvia. Adv. Pharmacol. Pharm., 2023, 11(2), 140-155. https://doi.org/ 10.13189/app.2023.110206 DOI: https://doi.org/10.13189/app.2023.110206
Baregama, C.; Goyal, A. Phytoconstituents, pharmacological activity, and medicinal use of Lepidium sativum Linn.: A review. Asian J. Pharm. Clin. Res., 2019, 12(4), 45-50. DOI: https://doi.org/10.22159/ajpcr.2019.v12i4.31292
Al-Snafi, A. E. Chemical constituents and pharmacological effects of lepidium sativum. Int. J. Curr. Pharm. Res., 2019, 11(6), 1-10. DOI: https://doi.org/10.22159/ijcpr.2019v11i6.36338
Mali, R. G.; Mahajan, S. G.; Mehta, A. A. Lepidium sativum (Garden cress): a review of contemporary literature and medicinal properties. Adv. Tradit. Med., 2007, 7(4), 331-335. https://doi.org/ 10.3742/OPEM.2007.7.4.331 DOI: https://doi.org/10.3742/OPEM.2007.7.4.331
Alok, S.; Jain, S. K.; Verma, A.; Kumar, M.; Mahor, A.; Sabharwal, M. Plant profile, phytochemistry and pharmacology of Asparagus racemosus (Shatavari): A review. Asian Pac. J. Trop. Dis., 2013, 3(3), 242-251. https://doi.org/10.1016/S2222-1808(13)60049-3 DOI: https://doi.org/10.1016/S2222-1808(13)60049-3
Shaha, P.; Bellankimath, A. Pharmacological profile of Asparagus racemosus: A review. Int. J. Curr. Microbiol. App. Sci., 2017, 6(11), 1215-23. DOI: https://doi.org/10.20546/ijcmas.2017.611.144
Mishra, J. N.; Verma, N. K. Asparagus racemosus: chemical constituents and pharmacological activities-a review. Eur. J. Biomed. Pharm. Sci., 2017, 4, 207-213.
Patel, S. S.; Saleem, T. M.; Ravi, V.; Shrestha, B.; Verma, N. K.; Gauthaman, K. Passiflora incarnata Linn: A phytopharmacological review. Int. J. Green Pharm., 2009, 3(4), 277-280.
Patel, S.; Verma, N.; Gauthaman, K. Passiflora incarnata Linn: A review on morphology, phytochemistry and pharmacological aspects. Phcog. Rev., 2009, 3(5), 186. DOI: https://doi.org/10.4103/0973-8258.59731
Tiwari, S.; Singh, S.; Tripathi, S.; Kumar, S. A pharmacological review: Passiflora species. Asian J. Pharm. Res., 2015, 5(4), 195-202. DOI: https://doi.org/10.5958/2231-5691.2015.00030.1
Mahmood, K. T.; Mugal, T.; Haq, I. U. Moringa oleifera: a natural gift-A review. J. Pharm. Sci. Res., 2010, 2(11), 775.
Bhattacharya, A.; Tiwari, P.; Sahu, P. K.; Kumar, S. A review of the phytochemical and pharmacological characteristics of Moringa oleifera. J. Pharm. Bioallied. Sci., 2018, 10(4), 181. https://doi.org/ 10.4103/JPBS.JPBS_126_18 DOI: https://doi.org/10.4103/JPBS.JPBS_126_18
Pareek, A.; Pant, M.; Gupta, M. M.; Kashania, P.; Ratan, Y.; Jain, V.; Chuturgoon, A. A. Moringa oleifera: An updated comprehensive review of its pharmacological activities, ethnomedicinal, phytopharmaceutical formulation, clinical, phytochemical, and toxicological aspects. Int. J. Mol. Sci., 2023, 24(3), 2098. https://doi.org/10.3390/ijms24032098 DOI: https://doi.org/10.3390/ijms24032098
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