Medicinal mushrooms: a comprehensive study on their antiviral potential
DOI:
https://doi.org/10.56782/pps.141Keywords:
Antivirals, Complementary medicine, Coronavirus, medicinal mushroom, Viral diseasesAbstract
Microbial diseases have become quite common in recent years. The interest in new antimicrobial drugs is increasing due to the possible side effects of synthetic drugs and the emergence of resistant microorganisms due to unconscious antimicrobial drug use. Mushrooms have the potential to be used as a natural resource in the fight against microorganisms. In this context, in this study, the effects of different fungal species against different viral diseases were compiled in the literature. According to the findings, it has been reported in the literature that many different mushroom species are effective against Herpes virus (HSV-1, HSV-2, BoHV-1, HCMV), Influenza (A, B, H1N1, H3N2, H5N1, H9N2) and Parainfluenza, Infectious bursal disease virus (IBDV), Poxvirus, Vaccinia virus, Poliovirus, Vesicular stomatitis viruses (VSV), Adenovirus, Syncytial virus (RSV), Dengue virus ( DENV-2), Human immunodeficiency virus (HIV), Hepatitis A, B, C virus, Feline calicivirus (FCV), Enterovirus, Coxsackievirus, Coronavirus, Infectious hematopoietic necrosis virus (IHNV), Newcastle disease virus (NDV) and Tobacco Mosaic virus (TMV). In this context, it is thought that mushrooms can be a very important natural resource against viruses.
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Bal, C.; Akgul, H.; Sevindik, M.; Akata, I.; Yumrutas, O. Determination of the anti-oxidative activities of six mushrooms. Fresenius Environ. Bull., 2017, 26(10), 6246-6252.
Sevindik, M. The novel biological tests on various extracts of Cerioporus varius. Fresenius Environ. Bull., 2019, 28(5), 3713-3717.
Sevindik, M.; Akgul, H.; Bal, C.; Selamoglu, Z. Phenolic contents, oxidant/antioxidant potential and heavy metal levels in Cyclocybe cylindracea. Indian J. Pharm. Educ. Res., 2018, 52(3), 437-441. https://doi.org/10.5530/ijper.52.3.50 DOI: https://doi.org/10.5530/ijper.52.3.50
Bal, C.; Sevindik, M.; Akgul, H.; Selamoglu, Z. Oxidative stress index and antioxidant capacity of Lepista nuda collected from Gaziantep/ Turkey. Sigma J. Engin. Nat. Sci., 2019, 37(1), 1-5.
Korkmaz, A. I.; Akgul, H.; Sevindik, M.; Selamoglu, Z. Study on determination of bioactive potentials of certain lichens. Acta Aliment., 2018, 47(1), 80-87. http://dx.doi.org/10.1556/066.2018.47.1.10 DOI: https://doi.org/10.1556/066.2018.47.1.10
Sevindik, M.; Akgül, H.; Dogan, M.; Akata, I.; Selamoglu, Z. Determination of antioxidant, antimicrobial, DNA protective activity and heavy metals content of Laetiporus sulphureus. Fresenius Environ. Bull., 2018, 27(3), 1946-1952.
Selamoglu, Z.; Sevindik, M.; Bal, C.; Ozaltun, B.; Sen, İ.; Pasdaran, A. Antioxidant, antimicrobial and DNA protection activities of phenolic content of Tricholoma virgatum (Fr.) P. Kumm. Biointerface Res. Appl. Chem., 2020, 10(3), 5500-5506. http://dx.doi.org/10.33263/BRIAC103.500506 DOI: https://doi.org/10.33263/BRIAC103.500506
Sevindik, M.; Akgul, H.; Selamoglu, Z.; Braidy, N. Antioxidant and antigenotoxic potential of Infundibulicybe geotropa mushroom collected from Northwestern Turkey. Oxid. Med. Cell. Longev., 2020, https://doi.org/10.1155/2020/5620484 DOI: https://doi.org/10.1155/2020/5620484
Mushtaq, W.; Baba, H.; Akata, I.; Sevindik, M. Antioxidant potential and element contents of wild edible mushroom Suillus granulatus. KSU J. Agric. Nat., 2020, 23(3), 592-595. http://dx.doi.org/10.18016/ksutarimdoga.vi.653241 DOI: https://doi.org/10.18016/ksutarimdoga.vi.653241
Sevindik, M.; Akata, I. Antioxidant, oxidant potentials and element content of edible wild mushroom Helvella leucopus. Indian J. Nat. Prod. Resour., 2020, 10(4), 266-271.
Saridogan, B. G. O.; Islek, C.; Baba, H.; Akata, I.; Sevindik, M. Antioxidant antimicrobial oxidant and elements contents of Xylaria polymorpha and X. hypoxylon (Xylariaceae). Fresenius Environ. Bull., 2021, 30(5), 5400-5404.
Sevindik, M.; Anticancer, antimicrobial, antioxidant and DNA protective potential of mushroom Leucopaxillus gentianeus (Quél.) Kotl. Indian J. Exp. Biol., 2021, 59(05), 310-315.
Eraslan, E. C.; Altuntas, D.; Baba, H.; Bal, C.; Akgül, H.; Akata, I.; Sevindik, M. Some biological activities and element contents of ethanol extract of wild edible mushroom Morchella esculenta. Sigma J. Engin. Nat. Sci., 2021, 39(1), 24-28.
Islek, C.; Saridogan, B. G. O.; Sevindik, M.; Akata, I. Biological activities and heavy metal contents of some Pholiota species. Fresenius Environ. Bull., 2021, 30(6), 6109-6114.
Sevindik, M.; Bal, C. Antioxidant, antimicrobial, and antiproliferative activities of wild mushroom, Laeticutis cristata (Agaricomycetes), from Turkey. Int. J. Med. Mushrooms, 2021, 23(11), 85-90. https://doi.org/10.1615/intjmedmushrooms.2021040415 DOI: https://doi.org/10.1615/IntJMedMushrooms.2021040415
Sevindik, M. Antioxidant and antimicrobial capacity of Lactifluus rugatus and its antiproliferative activity on A549 cells. Indian J. Tradit. Knowl., 2020, 19(2), 423-427. DOI: https://doi.org/10.56042/ijtk.v19i2.35356
Bal, C.; Baba, H.; Akata, I.; Sevindik, M.; Selamoglu, Z.; Akgül, H. Biological Activities of Wild Poisonous Mushroom Entoloma sinuatum (Bull.) P. Kumm (Boletales). KSU J. Agric. Nat., 2022, 25(1), 83-87. http://dx.doi.org/10.18016/ksutarimdoga.vi.880151 DOI: https://doi.org/10.18016/ksutarimdoga.vi.880151
Krupodorova, T.; Sevindik, M. Antioxidant potential and some mineral contents of wild edible mushroom Ramaria stricta. AgroLife Sci. J., 2020, 9(1), 186-191.
Karaltı, İ.; Eraslan, E. C.; Sarıdoğan, B. G. Ö.; Akata, I.; Sevindik, M. Total Antioxidant, Antimicrobial, Antiproliferative Potentials and Element Contents of Wild Mushroom Candolleomyces candolleanus (Agaricomycetes) from Turkey. Int. J. Med. Mushrooms, 2022, 24(12), 69-76. https://doi.org/10.1615/intjmedmushrooms.2022045389 DOI: https://doi.org/10.1615/IntJMedMushrooms.2022045389
Sevindik, M. Mushrooms as natural antiviral sources and supplements foods against coronavirus (COVID-19). J. Bacteriol. Mycol. Open Access, 2021, 9, 73-76. https://doi.org/10.15406/jbmoa.2021.09.00299 DOI: https://doi.org/10.15406/jbmoa.2021.09.00299
Sevindik, M.; Akgul, H.; Akata, I.; Alli, H.; Selamoglu, Z. Fomitopsis pinicola in healthful dietary approach and their therapeutic potentials. Acta Aliment., 2017, 46(4), 464-469. https://doi.org/10.1556/066.2017.46.4.9 DOI: https://doi.org/10.1556/066.2017.46.4.9
Baba, H.; Sevindik, M.; Dogan, M.; Akgül, H.; Antioxidant, antimicrobial activities and heavy metal contents of some Myxomycetes. Fresenius Environ. Bull., 2020, 29(09), 7840-7846.
Sevindik, M.; Investigation of antioxidant/oxidant status and antimicrobial activities of Lentinus tigrinus. Adv. Pharmacol. Sci., 2018, Art. No. 1718025. https://doi.org/10.1155%2F2018%2F1718025
Mohammed, F. S.; Uysal, I.; Sevindik, M. A Review on Antiviral Plants Effective against Different Virus Types. Prospects Pharm. Sci., 2023, 21(2), 1-21. https://doi.org/10.56782/pps.128 DOI: https://doi.org/10.56782/pps.128
Muylkens, B.; Thiry, J.; Kirten, P.; Schynts, F.; Thiry, E. Bovine herpesvirus 1 infection and infectious bovine rhinotracheitis. Vet. Res., 2007, 38(2), 181-209. https://doi.org/10.1051/vetres:2006059 DOI: https://doi.org/10.1051/vetres:2006059
Griffiths, P.; Baraniak, I.; Reeves, M. The pathogenesis of human cytomegalovirus. J. Pathol., 2015; 235(2), 288-297. https://doi.org/10.1002/path.4437 DOI: https://doi.org/10.1002/path.4437
Amoros, M.; Boustie, J.; Py, M. L.; Hervé, V.; Robin, V. Antiviral activity of Homobasidiomycetes: evaluation of 121 Basidiomycetes extracts on four viruses. Int. J. Pharmacogn., 1997, 35(4), 255-260. https://doi.org/10.1076/phbi.35.4.255.13308 DOI: https://doi.org/10.1076/phbi.35.4.255.13308
Mothana, R. A. A.; Ali, N. A.; Jansen, R.; Wegner, U.; Mentel, R.; Lindequist, U. Antiviral lanostanoid triterpenes from the fungus Ganoderma pfeifferi. Fitoterapia, 2003, 74(1-2), 177-180. https://doi.org/10.1016/s0367-326x(02)00305-2 DOI: https://doi.org/10.1016/S0367-326X(02)00305-2
Lee, S. M.; Kim, S. M.; Lee, Y. H.; Kim, W. J.; Park, J. K.; Park, Y. I.; Synytsya, A. Macromolecules isolated from Phellinus pini fruiting body: chemical characterization and antiviral activity. Macromol. Res., 2010, 18, 602-609. https://doi.org/10.1007/s13233-010-0615-9 DOI: https://doi.org/10.1007/s13233-010-0615-9
Minari, M. C.; Rincão, V. P.; Soares, S. A.; Ricardo, N. M. P. S.; Nozawa, C.; Linhares, R. E. C. Antiviral properties of polysaccharides from Agaricus brasiliensis in the replication of bovine herpesvirus 1. Acta Virol., 2011, 55(3), 255-259. https://doi.org/10.4149/av_2011_03_255 DOI: https://doi.org/10.4149/av_2011_03_255
Rincão, V. P.; Yamamoto, K. A.; Silva Ricardo, N. M. P.; Soares, S. A.; Paccola Meirelles, L. D.; Nozawa, C.; Carvalho Linhares, R. E. Polysaccharide and extracts from Lentinula edodes: structural features and antiviral activity. Virol. J., 2012, 9(1), 1-6. https://doi.org/10.1186%2F1743-422X-9-37 DOI: https://doi.org/10.1186/1743-422X-9-37
Santoyo, S.; Ramírez-Anguiano, A.C.; Aldars-García, L.; Reglero, G.; Soler-Rivas, C. Antiviral activities of Boletus edulis, Pleurotus ostreatus and Lentinus edodes extracts and polysaccharide fractions against Herpes simplex virus type 1. J. Food Nutr. Res., 2012, 51, 225–235.
Krupodorova, T.; Rybalko, S.; Barshteyn, V. Antiviral activity of Basidiomycete mycelia against influenza type A (serotype H1N1) and herpes simplex virus type 2 in cell culture. Virol. Sin., 2014, 29, 284-290. https://doi.org/10.1007/s12250-014-3486-y DOI: https://doi.org/10.1007/s12250-014-3486-y
Manoj, R.; Earanna, N.; Chandranaik, B. M. Molecular characterization of Trametes species and screening their aqueous extracts for antiviral properties. Biosci. Trends, 2017, 10(40), 8524-8529.
Doğan, H. H.; Karagöz, S.; Duman, R. In vitro evaluation of the antiviral activity of some mushrooms from Turkey. Int. J. Med. Mushrooms, 2018, 20(3), 201-212. https://doi.org/10.1615/intjmedmushrooms.2018025468 DOI: https://doi.org/10.1615/IntJMedMushrooms.2018025468
Roy, D.; Ansari, S.; Chatterjee, A.; Luganini, A.; Ghosh, S. K.; Chakraborty, N. In vitro search for antiviral activity against humancytomegalovirus from medicinal mushrooms Pleurotus sp. and Lentinus sp. J. Antivir. Antiretrovir, 2020, 12(3), 201. DOI: 10.35248/1948-5964.20.12.201
Elhusseiny, S. M.; El-Mahdy, T. S.; Awad, M. F.; Elleboudy, N. S.; Farag, M. M.; Aboshanab, K. M.; Yassien, M. A. Antiviral, cytotoxic, and antioxidant activities of three edible agaricomycetes mushrooms: Pleurotus columbinus, Pleurotus sajor-caju, and Agaricus bisporus. J. Fungi., 2021, 7(8), 645. https://doi.org/10.3390/jof7080645 DOI: https://doi.org/10.3390/jof7080645
Boudagga, S.; Bouslama, L.; Papetti, A.; Colombo, R.; Arous, F.; Jaouani, A. Antiviral activity of Inonotusin A an active compound isolated from Boletus bellinii and Boletus subtomentosus. Biologia, 2022, 77(12), 3645–3655. https://doi.org/10.1007%2Fs11756-022-01219-z DOI: https://doi.org/10.1007/s11756-022-01219-z
Tong, S.; Zhu, X.; Li, Y.; Shi, M.; Zhang, J.; Bourgeois, M.; Yang, H.; Chen, X.; Recuenco, S.; Gomez, J.; Chen, L.; Johnson, A.; Tao, Y.; Dreyfus, C.; Yu, W.; McBride, R.; Carney, P.J.; Gilbert, A.T.; Chang, J.; Guo, Z.; Davis, C.T.; Paulson, J.C.; Stevens, J.; Rupprecht, C.E.; Holmes, E.C.; Wilson, I.A.; Donis, R.O. New world bats harbor diverse influenza A viruses. PLoS Pathogens, 2013, 9(10), e1003657. https://doi.org/10.1128/genomea.00965-17 DOI: https://doi.org/10.1371/journal.ppat.1003657
Dadonaite, B.; Vijayakrishnan, S.; Fodor, E.; Bhella, D.; Hutchinson, E. C. Filamentous influenza viruses. J. Gen. Virol., 2016, 97(8), 1755. https://doi.org/10.1099/jgv.0.000535 DOI: https://doi.org/10.1099/jgv.0.000535
Novel Swine-Origin Influenza A (H1N1) Virus Investigation Team. (Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N. Engl. J. Med., 2009, 360(25), 2605-2615. https://doi.org/10.1056/nejmoa0903810 DOI: https://doi.org/10.1056/NEJMoa0903810
Jester, B. J.; Uyeki, T. M.; Jernigan, D. B. Fifty years of influenza A (H3N2) following the pandemic of 1968. Am. J. Public Health, 2020, 110(5), 669-676. https://doi.org/10.2105%2FAJPH.2019.305557 DOI: https://doi.org/10.2105/AJPH.2019.305557
Henrickson, K. J. Parainfluenza viruses. Clin. Microbiol. Rev., 2003, 16(2), 242-264. https://doi.org/10.1128/cmr.16.2.242-264.2003 DOI: https://doi.org/10.1128/CMR.16.2.242-264.2003
Teplyakova, T. V.; Psurtseva, N. V.; Kosogova, T. A.; Mazurkova, N. A.; Khanin, V. A.; Vlasenko, V. A. Antiviral activity of polyporoid mushrooms (higher Basidiomycetes) from Altai Mountains (Russia). Int. J. Med. Mushrooms, 2012, 14(1), 37-45. https://doi.org/10.1615/intjmedmushr.v14.i1.40 DOI: https://doi.org/10.1615/IntJMedMushr.v14.i1.40
Lee, S.; Kim, J. I.; Heo, J.; Lee, I.; Park, S.; Hwang, M. W.; Park, M. S. The anti-influenza virus effect of Phellinus igniarius extract. J. Microbiol., 2013, 51, 676-681. https://doi.org/10.1007/s12275-013-3384-2 DOI: https://doi.org/10.1007/s12275-013-3384-2
Gao, L.; Sun, Y.; Si, J.; Liu, J.; Sun, G.; Sun, X.; Cao, L. Cryptoporus volvatus extract inhibits influenza virus replication in vitro and in vivo. PLoS One, 2014, 9(12), e113604. https://doi.org/10.1371%2Fjournal.pone.0113604 DOI: https://doi.org/10.1371/journal.pone.0113604
Kuroki, T.; Lee, S.; Hirohama, M.; Taku, T.; Kumakura, M.; Haruyama, T.; Kawaguchi, A. Inhibition of influenza virus infection by Lentinus edodes mycelia extract through its direct action and immunopotentiating activity. Front. Microbiol., 2018, 9, 1164. https://doi.org/10.3389/fmicb.2018.01164 DOI: https://doi.org/10.3389/fmicb.2018.01164
Vlasenko, V.A., Ilyicheva, T. N., Teplyakova, T. V., Svyatchenko, S. V., Asbaganov, S. V., Zmitrovich, I. V., Vlasenko, A. V. Antiviral activity of total polysaccharide fraction of water and ethanol extracts of Pleurotus pulmonarius against the influenza A virus. Curr. Res. Environ. Appl. Mycol., 2020, 10(1), 224-235. https://doi.org/10.5943/cream/10/1/22 DOI: https://doi.org/10.5943/cream/10/1/22
Becht, H. Infectious bursal disease virus. Curr. Top. Microbiol. Immunol., 1980, 107-121. https://doi.org/10.1007/978-3-642-67717-5_5 DOI: https://doi.org/10.1007/978-3-642-67717-5_5
Johnston, J. B., & McFadden, G. (2003). Poxvirus immunomodulatory strategies: current perspectives. J. Virol., 2003, 77(11), 6093-6100. https://doi.org/10.1128%2FJVI.77.11.6093-6100.2003 DOI: https://doi.org/10.1128/JVI.77.11.6093-6100.2003
Kaynarcalidan, O.; Moreno Mascaraque, S.; Drexler, I. Vaccinia virus: from crude smallpox vaccines to elaborate viral vector vaccine design. Biomedicines, 2021, 9(12), 1780. https://doi.org/10.3390/biomedicines9121780 DOI: https://doi.org/10.3390/biomedicines9121780
Thompson, K. M.; Kalkowska, D. A. Review of poliovirus modeling performed from 2000 to 2019 to support global polio eradication. Expert Rev. Vaccines, 2020, 19(7), 661-686. https://doi.org/10.1080%2F14760584.2020.1791093 DOI: https://doi.org/10.1080/14760584.2020.1791093
Kidukuli, A. W.; Mbwambo, Z. H.; Malebo, H. M.; Mgina, C. A.; Mihale, M. J. In vivo antiviral activity, protease inhibition and brine shrimp lethality of selected Tanzanian wild edible mushrooms. J. Appl. Biosci., 2010, 31(1), 1887-1894.
Kandefer-Szerszeń, M.; Kawecki, Z.; Sałata, B.; Witek, M. Mushrooms as a source of substances with antiviral activity. Acta Mycol., 1980, 16(2), 215-220. https://doi.org/10.5586/am.1980.014 DOI: https://doi.org/10.5586/am.1980.014
Faccin, L. C.; Benati, F.; Rincão, V. P.; Mantovani, M. S.; Soares, S. A.; Gonzaga, M. L.; Carvalho Linhares, R. E. Antiviral activity of aqueous and ethanol extracts and of an isolated polysaccharide from Agaricus brasiliensis against poliovirus type 1. Lett. Appl. Microbiol., 2007, 45(1), 24-28. https://doi.org/10.1111/j.1472-765x.2007.02153.x DOI: https://doi.org/10.1111/j.1472-765X.2007.02153.x
Munis, A. M.; Bentley, E. M.; Takeuchi, Y. A tool with many applications: vesicular stomatitis virus in research and medicine. Expert. Opin. Biol. Ther., 2020, 20(10), 1187-1201. https://doi.org/10.1080/14712598.2020.1787981 DOI: https://doi.org/10.1080/14712598.2020.1787981
Gallardo, J.; Pérez-Illana, M.; Martín-González, N.; San Martín, C. Adenovirus structure: what is new?. Int. J. Mol. Sci., 2021, 22(10), 5240. https://doi.org/10.3390%2Fijms22105240 DOI: https://doi.org/10.3390/ijms22105240
Battles, M. B.; McLellan, J. S. Respiratory syncytial virus entry and how to block it. Nat. Rev. Microbiol., 2019, 17(4), 233-245. https://doi.org/10.1038/s41579-019-0149-x DOI: https://doi.org/10.1038/s41579-019-0149-x
Palomar, Q.; Xu, X.; Gondran, C.; Holzinger, M.; Cosnier, S.; Zhang, Z. Voltammetric sensing of recombinant viral dengue virus 2 NS1 based on Au nanoparticle–decorated multiwalled carbon nanotube composites. Microchimica Acta, 2020, 187, 1-10. https://doi.org/10.1007/s00604-020-04339-y DOI: https://doi.org/10.1007/s00604-020-04339-y
Takehara, M.; Kuida, K.; Mori, K. Antiviral activity of virus-like particles from Lentinus edodes (Shiitake). Arch. Virol., 1979, 59, 269-274. https://doi.org/10.1007/bf01317423 DOI: https://doi.org/10.1007/BF01317423
Zhu, Y. C.; Wang, G.; Yang, X. L.; Luo, D. Q.; Zhu, Q. C.; Peng, T.; Liu, J. K. Agrocybone, a novel bis-sesquiterpene with a spirodienone structure from basidiomycete Agrocybe salicacola. Tetrahedron Lett., 2010, 51(26), 3443-3445. https://doi.org/10.1016/j.tetlet.2010.04.128 DOI: https://doi.org/10.1016/j.tetlet.2010.04.128
Ellan, K.; Thayan, R.; Raman, J.; Hidari, K. I.; Ismail, N.; Sabaratnam, V. Anti-viral activity of culinary and medicinal mushroom extracts against dengue virus serotype 2: an in-vitro study. BMC Complement Altern. Med., 2019, 19, 1-12. https://doi.org/10.1186/s12906-019-2629-y DOI: https://doi.org/10.1186/s12906-019-2629-y
Lim, W. Z.; Cheng, P. G.; Abdulrahman, A. Y.; Teoh, T. C. The identification of active compounds in Ganoderma lucidum var. antler extract inhibiting dengue virus serine protease and its computational studies. J. Biomol. Struct. Dyn., 2020, 38(14), 4273-4288. https://doi.org/10.1080/07391102.2019.1678523 DOI: https://doi.org/10.1080/07391102.2019.1678523
Bharadwaj, S.; Lee, K. E.; Dwivedi, V. D.; Yadava, U.; Panwar, A.; Lucas, S. J.; Kang, S. G. Discovery of Ganoderma lucidum triterpenoids as potential inhibitors against Dengue virus NS2B-NS3 protease. Sci. Rep., 2019, 9(1), 19059. https://doi.org/10.1038/s41598-019-55723-5 DOI: https://doi.org/10.1038/s41598-019-55723-5
Douek, D. C.; Roederer, M.; Koup, R. A. Emerging concepts in the immunopathogenesis of AIDS. Annu. Rev. Med., 2009, 60, 471. https://doi.org/10.1146%2Fannurev.med.60.041807.123549 DOI: https://doi.org/10.1146/annurev.med.60.041807.123549
Powell, M. K., Benková, K., Selinger, P., Dogoši, M., Kinkorová Luňáčková, I., Koutníková, H., Laštíková, J.; Roubíčková, A.; Špůrková, Z.; Laclová, L.; Eis, V.; Šach, J.; Heneberg, P. Opportunistic infections in HIV-infected patients differ strongly in frequencies and spectra between patients with low CD4+ cell counts examined postmortem and compensated patients examined antemortem irrespective of the HAART era. PLoS One, 2016, 11(9), e0162704. https://doi.org/10.1371/journal.pone.0162704 DOI: https://doi.org/10.1371/journal.pone.0162704
Sharp, P. M., & Hahn, B. H.; The evolution of HIV-1 and the origin of AIDS. Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2010, 365(1552), 2487-2494. https://doi.org/10.1098%2Frstb.2010.0031 DOI: https://doi.org/10.1098/rstb.2010.0031
Board, N. L.; Moskovljevic, M.; Wu, F.; Siliciano, R. F.; Siliciano, J. D. Engaging innate immunity in HIV-1 cure strategies. Nat. Rev. Immunol., 2022, 22(8), 499-512. https://doi.org/10.1038/s41577-021-00649-1 DOI: https://doi.org/10.1038/s41577-021-00649-1
Sumba, J. D. GACOCA Formulation of East African wild mushrooms show promise in combating Kaposi's sarcoma and HIV/AIDS. Int. J. Med. Mushrooms, 2005, 7(3), 473-474. https://doi.org/10.1615/IntJMedMushrooms.v7.i3.1040 DOI: https://doi.org/10.1615/IntJMedMushr.v7.i3.1040
Wang, J.; Wang, H. X.; Ng, T. B. A peptide with HIV-1 reverse transcriptase inhibitory activity from the medicinal mushroom Russula paludosa. Peptides, 2007, 28(3), 560-565. https://doi.org/10.1016/j.peptides.2006.10.004 DOI: https://doi.org/10.1016/j.peptides.2006.10.004
El Dine, R. S.; El Halawany, A. M.; Ma, C. M.; Hattori, M. Anti-HIV-1 protease activity of lanostane triterpenes from the vietnamese mushroom Ganoderma colossum. J. Nat. Prod., 2008, 71(6), 1022-1026. https://doi.org/10.1021/np8001139 DOI: https://doi.org/10.1021/np8001139
Guo, H.; Sun, B.; Gao, H.; Chen, X.; Liu, S.; Yao, X.; Che, Y. Diketopiperazines from the Cordyceps-colonizing fungus Epicoccum nigrum. J. Nat. Prod., 2009, 72(12), 2115-2119. https://doi.org/10.1021/np900654a DOI: https://doi.org/10.1021/np900654a
Sato, N.; Zhang, Q.; Ma, C. M.; Hattori, M. Anti-human immunodeficiency virus-1 protease activity of new lanostane-type triterpenoids from Ganoderma sinense. Chem. Pharm. Bull., 2009, 57(10), 1076-1080. https://doi.org/10.1248/cpb.57.1076 DOI: https://doi.org/10.1248/cpb.57.1076
Jiang, Y.; Wong, J. H.; Fu, M.; Ng, T. B.; Liu, Z. K.; Wang, C. R.; Liu, F. Isolation of adenosine, iso-sinensetin and dimethylguanosine with antioxidant and HIV-1 protease inhibiting activities from fruiting bodies of Cordyceps militaris. Phytomedicine, 2011,18(2-3), 189-193. https://doi.org/10.1016/j.phymed.2010.04.010 DOI: https://doi.org/10.1016/j.phymed.2010.04.010
Adotey, G.; Quarcoo, A.; Holliday, J.; Fofie, S.; Saaka, B. Effect of immunomodulating and antiviral agent of medicinal mushrooms (immune assist 24/7 TM) on CD4+ T-lymphocyte counts of HIV-infected patients. Int. J. Med. Mushrooms, 2011, 13(2), 109-113. https://doi.org/10.1615/intjmedmushr.v13.i2.20 DOI: https://doi.org/10.1615/IntJMedMushr.v13.i2.20
Zhang, W.; Tao, J.; Yang, X.; Yang, Z.; Zhang, L.; Liu, H.; Wu, J. Antiviral effects of two Ganoderma lucidum triterpenoids against enterovirus 71 infection. Biochem. Biophys. Res. Commun., 2014, 449(3), 307-312. https://doi.org/10.1016/j.bbrc.2014.05.019 DOI: https://doi.org/10.1016/j.bbrc.2014.05.019
Flórez-Sampedro, L.; Zapata, W.; Orozco, L. P.; Mejía, A. I.; Arboleda, C.; Rugeles, M. T. In vitro anti-HIV-1 activity of the enzymatic extract enriched with laccase produced by the fungi Ganoderma sp. and Lentinus sp. Vitae, 2016, 23(2), 109-118. https://doi.org/10.17533/udea.vitae.v23n2a03 DOI: https://doi.org/10.17533/udea.vitae.v23n2a03
Lingala, S.; Ghany, M. G. Natural history of hepatitis C. Gastroenterol. Clin., 2015, 4(4), 717-734. https://doi.org/10.1016/j.gtc.2015.07.003 DOI: https://doi.org/10.1016/j.gtc.2015.07.003
Thomas, D. L. Global elimination of chronic hepatitis. N. Engl. J. Med., 2019, 380(21), 2041-2050. https://doi.org/10.1056/nejmra1810477 DOI: https://doi.org/10.1056/NEJMra1810477
Basra, S.; Anand, B. S. Definition, epidemiology and magnitude of alcoholic hepatitis. World J. Hepatol., 2011, 3(5), 108. https://doi.org/10.4254%2Fwjh.v3.i5.108 DOI: https://doi.org/10.4254/wjh.v3.i5.108
Terziroli Beretta-Piccoli, B.; Mieli-Vergani, G.; Vergani, D. Autoimmmune hepatitis. Cell. Mol. Immunol., 2022, 19(2), 158-176. https://doi.org/10.1038/s41423-021-00768-8 DOI: https://doi.org/10.1038/s41423-021-00768-8
Suleiman, W. B.; Shehata, R. M.; Younis, A. M. In vitro assessment of multipotential therapeutic importance of Hericium erinaceus mushroom extracts using different solvents. Bioresour. Bioprocess., 2022, 9(1), 1-13. https://doi.org/10.1186/s40643-022-00592-6 DOI: https://doi.org/10.1186/s40643-022-00592-6
Hsu, C. H.; Hwang, K. C.; Chiang, Y. H.; Chou, P. The mushroom Agaricus blazei Murill extract normalizes liver function in patients with chronic hepatitis B. J. Altern. Complement. Med., 2008, 14(3), 299-301. https://doi.org/10.1089/acm.2006.6344 DOI: https://doi.org/10.1089/acm.2006.6344
Gu, C. Q.; Li, J. W.; Chao, F. H. Inhibition of hepatitis B virus by D-fraction from Grifola frondosa: Synergistic effect of combination with interferon-α in HepG2 2.2. Antivir. Res., 2006, 72(2), 162-165. https://doi.org/10.1016/j.antiviral.2006.05.011 DOI: https://doi.org/10.1016/j.antiviral.2006.05.011
Li, Y. Q.; Zhang, K. C. In vitro inhibitory efects on HBsAg and HBeAg secretion of 3 new components produced by Ganoderma lucidum in the medium contained Radix sophorae flavescentis extract. Acta Microbiol. Sin., 2005, 45(4), 643-646.
Li, Y. Q.; Wang, S. F. Anti-hepatitis B activities of ganoderic acid from Ganoderma lucidum. Biotechnol. Lett., 2006, 28, 837-841. https://doi.org/10.1007/s10529-006-9007-9 DOI: https://doi.org/10.1007/s10529-006-9007-9
del Mar Delgado-Povedano, M.; de Medina, V. S.; Bautista, J.; Priego-Capote, F.; de Castro, M. D. L. Tentative identification of the composition of Agaricus bisporus aqueous enzymatic extracts with antiviral activity against HCV: A study by liquid chromatography–tandem mass spectrometry in high resolution mode. J. Funct. Foods, 2016, 24, 403-419. https://doi.org/10.1016/j.jff.2016.04.020 DOI: https://doi.org/10.1016/j.jff.2016.04.020
EL-Fakharany, E.; Haroun, B.; Ng, T.; Redwan, E. R. Oyster mushroom laccase inhibits hepatitis C virus entry into peripheral blood cells and hepatoma cells. Protein Pept. Lett., 2010, 17(8), 1031-1039. https://doi.org/10.2174/092986610791498948 DOI: https://doi.org/10.2174/092986610791498948
Gallego, P.; Rojas, Á.; Falcón, G.; Carbonero, P.; García-Lozano, M. R.; Gil, A.; Del Campo, J. A. Water-soluble extracts from edible mushrooms (Agaricus bisporus) as inhibitors of hepatitis C viral replication. Food Funct., 2019, 10(6), 3758-3767. https://doi.org/10.1039/C9FO00733D DOI: https://doi.org/10.1039/C9FO00733D
Sandargo, B.; Michehl, M.; Praditya, D.; Steinmann, E.; Stadler, M.; Surup, F. Antiviral meroterpenoid rhodatin and sesquiterpenoids rhodocoranes A–E from the Wrinkled Peach Mushroom, Rhodotus palmatus. Org. Lett., 2019, 21(9), 3286-3289. https://doi.org/10.1021/acs.orglett.9b01017 DOI: https://doi.org/10.1021/acs.orglett.9b01017
Peñaflor-Téllez, Y.; Chávez-Munguía, B.; Lagunes-Guillén, A.; Salazar-Villatoro, L.; Gutiérrez-Escolano, A. L. The feline calicivirus leader of the capsid protein has the functional characteristics of a viroporin. Viruses, 2022, 14(3), 635. https://doi.org/10.3390%2Fv14030635 DOI: https://doi.org/10.3390/v14030635
Lalani, S.; Poh, C. L. Flavonoids as antiviral agents for Enterovirus A71 (EV-A71). Viruses, 2020, 12(2), 184. https://doi.org/10.3390/v12020184 DOI: https://doi.org/10.3390/v12020184
Daba, T. M.; Zhao, Y.; Pan, Z. Advancement of mechanisms of coxsackie virus B3-induced myocarditis pathogenesis and the potential therapeutic targets. Curr. Drug Targets, 2019, 20(14), 1461-1473. https://doi.org/10.2174/1389450120666190618124722 DOI: https://doi.org/10.2174/1389450120666190618124722
Tian, J.; Hu, X.; Liu, D.; Wu, H.; Qu, L. Identification of Inonotus obliquus polysaccharide with broad-spectrum antiviral activity against multi-feline viruses. Int. J. Biol. Macromol., 2017, 95, 160-167. https://doi.org/10.1016/j.ijbiomac.2016.11.054 DOI: https://doi.org/10.1016/j.ijbiomac.2016.11.054
Seetaha, S.; Ratanabunyong, S.; Tabtimmai, L.; Choowongkomon, K.; Rattanasrisomporn, J.; Choengpanya, K. Anti-feline immunodeficiency virus reverse transcriptase properties of some medicinal and edible mushrooms. Vet. World, 2020, 13(9), 1798. https://doi.org/10.14202%2Fvetworld.2020.1798-1806 DOI: https://doi.org/10.14202/vetworld.2020.1798-1806
Zhao, C.; Gao, L.; Wang, C.; Liu, B.; Jin, Y.; Xing, Z. Structural characterization and antiviral activity of a novel heteropolysaccharide isolated from Grifola frondosa against enterovirus 71. Carbohydr. Polym., 2016, 144, 382-389. https://doi.org/10.1016/j.carbpol.2015.12.005 DOI: https://doi.org/10.1016/j.carbpol.2015.12.005
Ang, W. X.; Sarasvathy, S.; Kuppusamy, U. R.; Sabaratnam, V.; Tan, S. H.; Wong, K. T.; Ong, K. C. In vitro antiviral activity of medicinal mushroom Ganoderma neo-japonicum Imazeki against enteroviruses that caused hand, foot and mouth disease. Trop. Biomed., 2021, 38(3), 239-247. https://doi.org/10.47665/tb.38.3.063 DOI: https://doi.org/10.47665/tb.38.3.063
Rehman, M. F. U.; Akhter, S.; Batool, A. I.; Selamoglu, Z.; Sevindik, M.; Eman, R.; Aslam, M. Effectiveness of Natural Antioxidants against SARS-CoV-2? Insights from the In-Silico World. Antibiotics, 2021, 10(8), 1011. https://doi.org/10.3390%2Fantibiotics10081011 DOI: https://doi.org/10.3390/antibiotics10081011
Hu, B.; Guo, H.; Zhou, P.; Shi, Z. L. Characteristics of SARS-CoV-2 and COVID-19. Nat. Rev. Microbiol., 2021, 19(3), 141-154. https://doi.org/10.1038/s41579-020-00459-7 DOI: https://doi.org/10.1038/s41579-020-00459-7
Elhusseiny, S. M.; El-Mahdy, T. S.; Elleboudy, N. S.; Yahia, I. S.; Farag, M. M.; Ismail, N. S.; Aboshanab, K. M. In vitro Anti SARS-CoV-2 Activity and Docking Analysis of Pleurotus ostreatus, Lentinula edodes and Agaricus bisporus Edible Mushrooms. Infect. Drug Resist., 2022, 15, 3459-3475. https://doi.org/10.2147/idr.s362823 DOI: https://doi.org/10.2147/IDR.S362823
Teplyakova, T. V.; Pyankov, O. V.; Safatov, A. S.; Ovchinnikova, A. S.; Kosogova, T. A.; Skarnovich, M. O.; Poteshkina, A. L. Water Extract of the Chaga Medicinal Mushroom, Inonotus obliquus (Agaricomycetes), Inhibits SARS-CoV-2 Replication in Vero E6 and Vero Cell Culture Experiments. Int. J. Med. Mushrooms, 2022, 24(2), 23-30. https://doi.org/10.1615/IntJMedMushrooms.2021042012 DOI: https://doi.org/10.1615/IntJMedMushrooms.2021042012
Sen, D.; Debnath, B.; Debnath, P.; Debnath, S., Zaki, M. E.; Masand, V. H. Identification of potential edible mushroom as SARS-CoV-2 main protease inhibitor using rational drug designing approach. Sci. Rep., 2022, 12(1), 1503. https://doi.org/10.1038/s41598-022-05349-x DOI: https://doi.org/10.1038/s41598-022-05349-x
Basal, W. T.; Elfiky, A.; Eid, J. Chaga medicinal mushroom Inonotus obliquus (agaricomycetes) terpenoids may interfere with SARS-CoV-2 spike protein recognition of the host cell: a molecular docking study. Int. J. Med. Mushrooms, 2021, 23(3), 1-14. https://doi.org/10.1615/intjmedmushrooms.2021037942 DOI: https://doi.org/10.1615/IntJMedMushrooms.2021037942
Rangsinth, P.; Sillapachaiyaporn, C.; Nilkhet, S.; Tencomnao, T.; Ung, A. T.; Chuchawankul, S. Mushroom-derived bioactive compounds potentially serve as the inhibitors of SARS-CoV-2 main protease: An in silico approach. J. Tradit. Complement. Med., 2021, 11(2), 158-172. https://doi.org/10.1016/j.jtcme.2020.12.002 DOI: https://doi.org/10.1016/j.jtcme.2020.12.002
AL-jumaili, M. M. O.; Al-dulaimi, F. K.; Ajeel, M. A. The role of Ganoderma lucidum uptake on some hematological and immunological response in patients with coronavirus (COVID-19). Sys. Rev. Pharm., 2020, 11, 537-541. DOI: https://doi.org/10.24926/iip.v11i2.3249
Jan, J. T.; Cheng, T. J. R.; Juang, Y. P.; Ma, H. H.; Wu, Y. T.; Yang, W. B.; Wong, C. H. Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection. Proc. Natl. Acad. Sci., 2021, 118(5), e2021579118. https://doi.org/10.1073/pnas.2021579118 DOI: https://doi.org/10.1073/pnas.2021579118
Rahman, M. A.; Rahman, M. S.; Bashir, N. M. B.; Mia, R.; Hossain, A.; Saha, S. K.; Sarker, N. C. Rationalization of mushroom-based preventive and therapeutic approaches to COVID-19. Int. J. Med. Mushrooms, 2021, 23(5), 1-11. https://doi.org/10.1615/intjmedmushrooms.2021038285 DOI: https://doi.org/10.1615/IntJMedMushrooms.2021038285
Senthil Kumar, K. J.; Gokila Vani, M.; Hsieh, H. W.; Lin, C. C.; Wang, S. Y. Antcins from Antrodia cinnamomea and Antrodia salmonea inhibit angiotensin-converting enzyme 2 (ACE2) in epithelial cells: Can be potential candidates for the development of SARS-CoV-2 prophylactic agents. Plants, 2021, 10(8), 1736. https://doi.org/10.3390/plants10081736 DOI: https://doi.org/10.3390/plants10081736
Hu, Y.; Chen, W.; Shen, Y.; Zhu, B.; Wang, G. X. Synthesis and antiviral activity of coumarin derivatives against infectious hematopoietic necrosis virus. Bioorg. Med. Chem., 2019, 29(14), 1749-1755. https://doi.org/10.1016/j.bmcl.2019.05.019 DOI: https://doi.org/10.1016/j.bmcl.2019.05.019
Burman, B.; Pesci, G.; Zamarin, D. Newcastle disease virus at the forefront of cancer immunotherapy. Cancers, 2020, 12(12), 3552. https://doi.org/10.3390/cancers12123552 DOI: https://doi.org/10.3390/cancers12123552
Lee, K. Z.; Basnayake Pussepitiyalage, V.; Lee, Y. H.; Loesch‐Fries, L. S.; Harris, M. T.; Hemmati, S.; Solomon, K. V. Engineering tobacco mosaic virus and its virus‐like‐particles for synthesis of biotemplated nanomaterials. Biotechnol. J., 2021, 16(4), 2000311. https://doi.org/10.1002/biot.202000311 DOI: https://doi.org/10.1002/biot.202000311
Ren, G.; Xu, L.; Lu, T.; Yin, J. Structural characterization and antiviral activity of lentinan from Lentinus edodes mycelia against infectious hematopoietic necrosis virus. Int. J. Biol. Macromol., 2018, 115, 1202-1210. https://doi.org/10.1016/j.ijbiomac.2018.04.132 DOI: https://doi.org/10.1016/j.ijbiomac.2018.04.132
Lee, D.; Boo, K. H.; Lee, J. M.; Viet, C. D.; Quyen, N.; Unno, T.; Lee, D. S. Anti-viral activity of Hydnellum concrescens, a medicinal mushroom. Afri. J. Biotechnol., 2012, 11(86), 15241-15245.
Shamaki, B. U.; Sandabe, U. K.; Ogbe, A. O.; Abdulrahman, F. I.; El-Yuguda, A. D. Methanolic soluble fractions of lingzhi or reishi medicinal mushroom, Ganoderma lucidum (Higher basidiomycetes) Extract inhibit neuraminidase activity in newcastle disease virus (LaSota). Int. J. Med. Mushrooms, 2014, 16(6), 579-583. https://doi.org/10.1615/intjmedmushrooms.v16.i6.70 DOI: https://doi.org/10.1615/IntJMedMushrooms.v16.i6.70
Wang, M.; Meng, X.; Yang, R.; Qin, T.; Li, Y.; Zhang, L.; Fei, C.; Zhen, W.; Zhang, K.; Wang, X.; Hu, Y.; Xue, F. Cordyceps militaris polysaccharides can improve the immune efficacy of Newcastle disease vaccine in chicken. Int. J. Biol. Macromol., 2013, 59, 178-183. https://doi.org/10.1016/j.ijbiomac.2013.04.007 DOI: https://doi.org/10.1016/j.ijbiomac.2013.04.007
Yan, H.; Rong, X.; Chen, P. T.; Zhang, X.; Ma, Z. Q. Two new steroids from sclerotia of the fungus Omphalia lapidescens. J. Asian Nat. Prod. Res., 2014, 16(3), 265-270. https://doi.org/10.1080/10286020.2013.874346 DOI: https://doi.org/10.1080/10286020.2013.874346
Aoki, M.; Tan, M.; Fukushima, A.; Hieda, T.; Kubo, S.; Takabayashi, M.; Mikami, Y. Antiviral substances with systemic effects produced by Basidiomycetes such as Fomes fomentarius. Biosci. Biotechnol. Biochem., 1993, 57(2), 278-282. https://doi.org/10.1271/bbb.57.278 DOI: https://doi.org/10.1271/bbb.57.278
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