Zarys historii syntezy leków ze szczególnym uwzględnieniem leków przeciwnowotworowych i przeciwbakteryjnych

Joanna Warguła

doi:10.56782/pps.121

Data publikacji : 2022-11-08

Tom 20 Nr 3 (2022)

Zarys historii syntezy leków ze szczególnym uwzględnieniem leków przeciwnowotworowych i przeciwbakteryjnych

Joanna Warguła

DOI: https://doi.org/10.56782/pps.121

Abstrakt

W pracy przedstawiono zarys historyczny rozwoju leków od czasów najdawniejszych do czasów obecnych, starając się uwzględnić zarówno drogę jaką przebyto od poznania właściwości leczniczych surowca, przez wskazanie konkretnych związków aktywnych z niego wyizolowanych, po identyfikację celu biologicznego. Na przykładzie syntezy pierwszych chemicznych środków leczniczych wskazano kierunki badań i tok rozumowania ówczesnych naukowców. Omawiając historię środków przeciwbakteryjnych, nakreślono drogę, jaką przebyto od przypadkowego odkrycia Fleminga, po organiczną syntezę związków o innej niż przeciwdrobnoustrojowa aktywności biologicznej. Fakt ten zazębia się z historią rozwoju leków przeciwnowotworowych, którą zarysowano z uwzględnieniem głównych mechanizmów działania.

Słowa kluczowe:

synteza, leki przeciwbakteryjne, leki przeciwnowotworowe

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Warguła, J. (2022). Zarys historii syntezy leków ze szczególnym uwzględnieniem leków przeciwnowotworowych i przeciwbakteryjnych. Prospects in Pharmaceutical Sciences, 20(3), 1–10. https://doi.org/10.56782/pps.121

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