REVIEW OF CURRENT GUIDELINES AND STUDIES ON USE OF ACETYLSALICYLIC ACID IN THE PRIMARY CARDIOVASCULAR EVENTS PREVENTION
DOI:
https://doi.org/10.56782/pps.29Keywords:
acetylsalicylic acid, prevention, cardiovascular events, glycineAbstract
Acetylsalicylic acid is a medicinal substance common use in medicine. The property of inhibiting platelet aggregation is widely used in the prevention of cardiovascular diseases. The role of acetylsalicylic acid is well established in the prevention of secondary cardiovascular events, while in the primary prevention of cardiovascular events, the opinions of researchers and cardiology association are divided. In the presented studies, acetylsalicylic acid reduced the risk of cardiovascular episodes, however, the risk of bleeding was often greater than the benefits of aspirin in primary prevention. There are many acetylsalicylic acid products available on the market. In order to minimize the risk of local irritation in the gastrointestinal tract, the use of film-coated formulations should be considered. The combination of acetylsalicylic acid and glycine seems promising, which increases the solubility of acetylsalicylic acid and has protective properties.
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