SUBSTANCJE PROMIENIOCHRONNE A ŚRODOWISKO PRZYRODNICZE

Grzegorz Nałęcz-Jawecki; Tomasz Zawadzki; Agata Skrzypczak

doi:10.56782/pps.90

Published : 2012-09-17

Vol. 10 No. 5 (2012)

SUNSCREENS AND THE ENVIROMENT

Grzegorz Nałęcz-Jawecki

Tomasz Zawadzki

Agata Skrzypczak

DOI: https://doi.org/10.56782/pps.90

Abstract

Sunscreens or uv-filters are used in cosmetics and in materials as protection against uv-radiation. The widespread occurrence of sunscreens in aquatic environment has been reported in many countries. The UV-filters have been detected in influents and effluents of wastewater treatment plants, freshwaters and in tissues of the aquatic organisms. For some filters, mainly benzophenons, hormonal activity has been documented in vitro and in vivo. The goal of our study was the evaluation of the genotoxicity of selected sunscreens in the short-term bacterial screening assays. Our results indicated that 12 tested sunscreens were not mutagenic or photomutagenic in Ames MPF™ assay. However, 2-ethylhexyl-4-methoxycinnamate and methoxycinnamonic acid irradiated with UVA were genotoxic in umu-test after s9 metabolic activation.

Keywords:

estrogenicity, genotoxicity, sunscreens, UV-filters

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Nałęcz-Jawecki, G., Zawadzki, T., & Skrzypczak, A. (2012). SUNSCREENS AND THE ENVIROMENT. Prospects in Pharmaceutical Sciences, 10(5), 32–39. https://doi.org/10.56782/pps.90

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Grzegorz Nałęcz-Jawecki

Affiliation:

Zakład Badania Środowiska, Wydział Farmaceutyczny Warszawski Uniwersytet Medyczny, Poland

Tomasz Zawadzki

Affiliation:

Zakład Badania Środowiska, Wydział Farmaceutyczny Warszawski Uniwersytet Medyczny Poland

Agata Skrzypczak

Affiliation:

Zakład Badania Środowiska, Wydział Farmaceutyczny Warszawski Uniwersytet Medyczny, Poland