SUNSCREENS AND THE ENVIROMENT
DOI:
https://doi.org/10.56782/pps.90Keywords:
estrogenicity, genotoxicity, sunscreens, UV-filtersAbstract
Sunscreens or uv-filters are used in cosmetics and in materials as protection against uv-radiation. The widespread occurrence of sunscreens in aquatic environment has been reported in many countries. The UV-filters have been detected in influents and effluents of wastewater treatment plants, freshwaters and in tissues of the aquatic organisms. For some filters, mainly benzophenons, hormonal activity has been documented in vitro and in vivo. The goal of our study was the evaluation of the genotoxicity of selected sunscreens in the short-term bacterial screening assays. Our results indicated that 12 tested sunscreens were not mutagenic or photomutagenic in Ames MPF™ assay. However, 2-ethylhexyl-4-methoxycinnamate and methoxycinnamonic acid irradiated with UVA were genotoxic in umu-test after s9 metabolic activation.
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