EGZOSOMY JAKO NOŚNIKI INFORMACJI W KOMUNIKACJI MIĘDZY KOMÓRKAMI NOWOTWOROWYMI

Aleksandra Grzybowska; Tomasz Lorenc; Wioletta Olejarz; Grażyna Nowicka

doi:10.56782/pps.32

Data publikacji : 2019-08-07

Tom 17 Nr 2 (2019)

EGZOSOMY JAKO NOŚNIKI INFORMACJI W KOMUNIKACJI MIĘDZY KOMÓRKAMI NOWOTWOROWYMI

Aleksandra Grzybowska

Tomasz Lorenc

Wioletta Olejarz

Grażyna Nowicka

DOI: https://doi.org/10.56782/pps.32

Abstrakt

Egzosomy to sferyczne nanopęcherzyki błonowe uwalniane niemal przez wszystkie typy komórek. Jako struktury zawierające bogaty panel bioaktywnych cząsteczek pośredniczą w wymianie informacji oraz transporcie składników między komórkami, inicjując lub modulując określone procesy, zarówno fizjologiczne, jak i patologiczne. Egzosomy posiadają ogromny potencjał do wykorzystania ich w diagnostyce, zapobieganiu oraz leczeniu wielu chorób, w tym nowotworów. W pracy przedstawiono aktualną wiedzę na temat egzosomów, uwzględniając w szczególności ich rolę w komunikacji między komórkami nowotworowymi oraz możliwości zastosowania w diagnostyce oraz terapii onkologicznej.

Słowa kluczowe:

egzosomy, zewnątrzkomórkowe pęcherzyki błonowe, biomarkery, komunikacja międzykomórkowa, nowotwór, leki onkologiczne

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Grzybowska, A., Lorenc, T., Olejarz, W., & Nowicka, G. (2019). EGZOSOMY JAKO NOŚNIKI INFORMACJI W KOMUNIKACJI MIĘDZY KOMÓRKAMI NOWOTWOROWYMI. Prospects in Pharmaceutical Sciences, 17(2), 6–13. https://doi.org/10.56782/pps.32

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Utwór dostępny jest na licencji Creative Commons Uznanie autorstwa 4.0 Międzynarodowe.

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