CZY NADWAGA LUB NIEDOWAGA MŁODYCH ZDROWYCH KOBIET W OKRESIE PREKONCEPCYJNYM MOŻE PROGNOZOWAĆ ZABURZONĄ HOMEOSTAZĘ HORMONÓW TARCZYCY ORAZ SKŁADU BIAŁEK W SUROWICY

Agnieszka Strawa; Ewa Skarżyńska; Barbara Lisowska-Myjak

doi:10.56782/pps.4

Published : 2022-06-09

Vol. 20 No. 1 (2022)

Can overweight or underweight in young healthy women in the pre-conception period predict disturbed homeostasis of thyroid hormones and protein composition in serum?

Agnieszka Strawa

Ewa Skarżyńska

Barbara Lisowska-Myjak

DOI: https://doi.org/10.56782/pps.4

Abstract

The aim of this study was to determine the influence of underweight, normal body weight and overweight in pre-conception period on thyroid hormones status and electrophoretic composition of serum proteins. During the study concentration profile of thyroid hormones (TSH, fT3, fT4) and proteins located in 6 electrophoretic fractions was assesed. Obtained results showed no significant differences in TSH levels, the most specific marker of primary thyroid diseases, between underweight women, normal weight and overweight. Possibility of using BMI measurement to assess altered thyroid function in study group was therefore excluded. On the other hand, thyroid hormones have a direct influence on regulation of metabolic homeostasis in both overweight and underweight women, by various mechanisms.

KEYWORDS: body weight, thyroid hormones, young women, pre-contraceptive age, serum protein electrophoresis.

Keywords:

body weight, thyroid hormones, young women, pre-contraceptive age, serum protein electrophoresis

Similar Articles

Girish B S, Srinivasan R, Joel M. Johns, C S Meghana, Adaptability of clinical pharmacist led interventions in the management of anemia of chronic renal disease: optimizing care , Prospects in Pharmaceutical Sciences: Vol. 22 No. 3 (2024)
Szymon Barczak, Barbara Badura, Agnieszka Lembas, Tomasz Mikuła, Alicja Wiercińska-Drapało, Severe course of HIV-related Kaposi’s sarcoma with cutaneous, visceral and oral manifestations in a late-presenting patient , Prospects in Pharmaceutical Sciences: Vol. 22 No. 2 (2024)
Helena E. Makulska-Nowak, ALCOHOL VERSUS CANNABIS - COMPARISON OF RISK , Prospects in Pharmaceutical Sciences: Vol. 11 No. 6 (2013)
Justyna Śledź, ORAL CAVITY CANCER - EPIDEMIOLOGICAL DATA AND RISK FACTORS , Prospects in Pharmaceutical Sciences: Vol. 13 No. 2 (2015)
Paulina Brewczyńska, Justyna Makowska, Dorota Skrajnowska, Marta Teryks, Andrzej Tokarz, ADDICTION TO CONVENTIONAL AND ELECTRONIC CIGARETTES AND THE RISKS OF PHARMACOTHERAPY IN SMOKERS. , Prospects in Pharmaceutical Sciences: Vol. 13 No. 3 (2015)
Mateusz Karasiewicz, Sylwester Krukowski, CITRATE IONS – THEIR PHYSIOLOGICAL FUNCTIONS, PHARMACOTHERAPEUTIC APPLICATIONS, AND POTENTIAL ROLE IN BIOMATERIALS ENGINEERING , Prospects in Pharmaceutical Sciences: Vol. 14 No. 5 (2016)
Marta Oleszczuk, NUCLEAR MAGNETIC RESONANCE IN THE STRUCTURAL INVESTIGATION OF BIOMOLECULES: APPLICATION IN THE STUDY OF MODEL HELICAL SYSTEMS , Prospects in Pharmaceutical Sciences: Vol. 4 No. 1 (2006)
Elżbieta Gniazdowska, Edyta Gilant, Katarzyna Buś-Kwaśnik, ICH M10 guideline - a harmonized global approach to bioanalysis , Prospects in Pharmaceutical Sciences: Vol. 21 No. 3 (2023)
Agata Pisula, Agnieszka Sienicka, Agnieszka Dobrowolska-Redo, Joanna Kacperczyk-Bartnik, Ewa Romejko-Wolniewicz, PARP inhibitors in ovarian cancer therapy , Prospects in Pharmaceutical Sciences: Vol. 22 No. 2 (2024)
Bartłomiej Kot, Mateusz Moczulski, Agnieszka Czajkowska, Arkadiusz Kocur, Pharmacotherapy of apnea in the premature neonatological subpopulation – therapeutic opportunities, pharmacokinetic implications and recommendations for therapeutic drug monitoring , Prospects in Pharmaceutical Sciences: Vol. 22 No. 2 (2024)

<< < 1 2 3 4 5 > >>

You may also start an advanced similarity search for this article.

Details

References

Statistics

Authors

Download files

PDF (Język Polski)

Citation rules

Strawa, A., Skarżyńska, E., & Lisowska-Myjak, B. (2022). Can overweight or underweight in young healthy women in the pre-conception period predict disturbed homeostasis of thyroid hormones and protein composition in serum?. Prospects in Pharmaceutical Sciences, 20(1), 1–10. https://doi.org/10.56782/pps.4

Altmetric indicators

Cited by / Share

Licence

This work is licensed under a Creative Commons Attribution 4.0 International License.

References

Do J.G., Park C.H., Lee Y.T., Yoon K.J.. Association between underweight and pulmonary function in 282,135 healthy adults: Across-sectional study in Korean population. Sci Rep, 2019, 9, 14308 DOI: https://doi.org/10.1038/s41598-019-50488-3

Kawicka A., Regulska-Ilow B. Metabolic disorders and nutritional status in autoimmune thyroid diseases. Postepy Hig Med Dosw (online), 2015, 69, 80-90 DOI: https://doi.org/10.5604/17322693.1136383

Spann M.N., Scheinost D., Feng T., Barbato K., Lee S., Monk C., Peterson B.S. Association of maternal prepregnancy body mass index with fetal growth and neonatal thalamic brain connectivity among adolescent and young women. JAMA Network open, 2020, 3 DOI: https://doi.org/10.1001/jamanetworkopen.2020.24661

Gamit A.M., Khubchandani A.S., Gamit M.R., Parmar U., Adarsh A., Gaadhe P. A study of serum total protein, serum albumin and thyroid hormones in protein-energy malnutrition in children. In J Med Sci Public Health, 2017, 6, 409-412 DOI: https://doi.org/10.5455/ijmsph.2017.15082016633

Young M.F., Ramakrishnan U. Maternal undernutrition before and during pregnancy and offspring health and development. Ann Nutr Metab, 2020, 76, 41-53 DOI: https://doi.org/10.1159/000510595

Weir C.B., Jan A. BMI Classification Percentile And Cut Off Points. In: StatPearls. Treasure Island (FL): StatPearls Publishing, 2021

Lisowska-Myjak B., Puchalska A., Hałasa N., Płazińska M., Strawa A. The association between clinical and laboratory parameters in thyroid disease and nonthyroidal illness in young women. Eur Rev Med Pharmacol Sci, 2019, 23, 2950-2959

Kim O.Y., Shin M.J., Moon J., Chung J.H. Plasma ceruloplasmin as a biomarker for obesity: a proteomic approach. Clinical Biocheistry, 2011, 44, 351-356 DOI: https://doi.org/10.1016/j.clinbiochem.2011.01.014

Teede H.J., Joham A.E., Paul E., Moran L.J., Loxton D., Jolley D., Lombard C. Longitudinal weight gain in women identified with polycystic ovary syndrome: results of an observational study in young women. Obesity, 2013, 21 DOI: https://doi.org/10.1002/oby.20213

Bharadwaj S., Ginoya S., Tandon P., Gohel T.D., Guirguis J., Vallabh H., Jevenn A., Hanouneh I. Manutrition: laboratory markers vs nutrional assessment. Gastroenterology Report, 2016, 4, 272-280 DOI: https://doi.org/10.1093/gastro/gow013

Warren M.P. Endocrine manifestations of eating disorders. J Clin Endocrinol Metab, 2011, 96, 333-343 DOI: https://doi.org/10.1210/jc.2009-2304

Banh L. Serum proteins as markers of nutrition: what are we treating? Practical gastroenterology, 2006, 43, 47-64

Scott S.P., Murray-Kolb L.E. Iron status is associated with performance on executive functioning tasks in nonanemic young women. J Nutr, 2016, 146, 30-37 DOI: https://doi.org/10.3945/jn.115.223586

Beck K.L., Conlon C.A., Kruger R., Coad J. Dietary determinants of and possible solutions to iron deficiency for yoiung women living in industrialized countries: a review. Nutrients, 2014, 6, 3747-3776 DOI: https://doi.org/10.3390/nu6093747

Calkins K., Devaskar S.U. Fetal origins of adult disease. Curr Probl Pediatr Adolesc Health Care, 2011, 41, 158-176 DOI: https://doi.org/10.1016/j.cppeds.2011.01.001

Gademan M.G.J, van Eijsden M., Roseboom T.J., van der Post J.A.M., Stronks K., Vrijkotte T.G.M. Maternal prepregnancy body mass index and their children’s blood pressure and resting cardiac autonomic balance at age 5 to 6 years. Hypertension, 2013, 62, 641-647 DOI: https://doi.org/10.1161/HYPERTENSIONAHA.113.01511

Torloni M.R., Betran A.P., Horta B.L., Nakamura M.U., Atallah A.N., Moron A.F., Valente O. Prepregnancy BMI and the risk of gestational diabetes: a systematic review of the literature with meta-analysis. Obesity reviews, 2009, 10, 194-203 DOI: https://doi.org/10.1111/j.1467-789X.2008.00541.x

Cox B., Luyten L.J., Dockx Y., Provost E., Madhloum N., De Boever P., Neven K.Y., Sassi F., Sleurs H., Vrijens K., Vineis P., Plusquin M., Nawrot T.S. Association between maternal prepregnancy body mass index and anthropometric parameters, blood pressure, and retinal microvasculature in children age 4 to 6 years. JAMA Netw Open, 2020, 3: e204662 DOI: https://doi.org/10.1001/jamanetworkopen.2020.4662

Ruiz-Núñez B., Tarasse R., Vogelaar E.F., Dijck-Brouwer D.A.J, Muskiet F.A.J. Higher Prevalence of “Low T3 Syndrome” in Patients With Chronic Fatigue Syndrome: A Case–Control Study. Front Endocrinol, 2018, 9, 97 DOI: https://doi.org/10.3389/fendo.2018.00097

Du X., Pan B., Li W., Zou Y., Hua X., Huang W., Wan X., Cao C. Albuminuria is a independent risk factor of T4 elevation in chronic kidney diseae. Sci Rep, 2017, 7, 41302 DOI: https://doi.org/10.1038/srep41302

Ponichtera A., Borowiak E. Choroby tarczycy jako poważny problem medyczny w Polsce. Problemy Pielęgniarstwa, 2008, 16, 192 – 198

Mullur R., Liu Y.Y., Brent G.A. Thyroid hormone regulation of metabolism. Physiol Rev, 2014, 94, 355- 382 DOI: https://doi.org/10.1152/physrev.00030.2013

Ciciatiello A.G., Di Girolamo D., Dentice M. Metabolic effects of the intracellular regulation of thyroid hormone: old players, new concepts. Front Endocrinol, 2018, 9, 474 DOI: https://doi.org/10.3389/fendo.2018.00474

Krekora-Wollny K. Niedoczynność tarczycy a otyłość. Forum Zaburzeń Metabolicznych, 2010, 1, 63-65

Alfadda A.A., Benabdelkamel H., Masood A., Jammah A.A., Ekhzaimy A.A. Differences in the plasma proteome of patients with hypothyroidism before and after thyroid hormone replacement: a proteomic analysis. Int J Mol Sci, 2018, 19, E88 DOI: https://doi.org/10.3390/ijms19010088

Dahiya K., Verma M., Dhakhar R., Ghalaut V.S., Ghalaut P.S., Sachdeva A., Malik I., Kumar R. Thyroid profile and iron metabolism: mutual relationship in hypothyroidism. Biomedical Res, 2016, 27

Lin K.H., Lee H.Y., Shih C.H., Yen C.C., Chen S.L., Yang R.C., Wang C.S. Plasma protein regulation by thyroid hormone. J Endocrinol, 2003, 179, 367-377 DOI: https://doi.org/10.1677/joe.0.1790367

Agnieszka Strawa

agnieszka.strawa@yahoo.com

Affiliation:

Katedra Biochemii i Chemii Klinicznej, Wydział Farmaceutyczny, Warszawski Uniwersytet Medyczny, ul. Banacha 1, 02-097 Warszawa Poland

Ewa Skarżyńska

Affiliation:

Katedra Biochemii i Chemii Klinicznej, Wydział Farmaceutyczny, Warszawski Uniwersytet Medyczny Poland

Barbara Lisowska-Myjak

Affiliation:

Katedra Biochemii i Chemii Klinicznej, Wydział Farmaceutyczny, Warszawski Uniwersytet Medyczny Poland

Can overweight or underweight in young healthy women in the pre-conception period predict disturbed homeostasis of thyroid hormones and protein composition in serum?

Agnieszka Strawa

Ewa Skarżyńska

Barbara Lisowska-Myjak

Abstract

Keywords:

Most read articles by the same author(s)

Similar Articles

Agnieszka Strawa

Ewa Skarżyńska

Barbara Lisowska-Myjak