English
Język Polski
BREAST CANCER DISEASE AND NEW COMPOUNDS WITH ANTICANCER ACTIVITY
Paweł Żero
Maria Niemyjska
Magdalena Rasztawicka
Dorota Maciejewska
Abstract
Breast cancer is the most common women’s malignant tumour. Many drugs used in chemotherapy are hazardous because of side-effects, therefore, the search for new active compounds is advisable. 3,3’-diindolilomethane (DIM) is known to inhibit DNA synthesis and cell proliferation in human breast cancer cells. It is a natural product produced during the autolytic breakdown of glucobrassicin, that occurs in Crucifereae (cabbage, Brussels sprouts, cauliflower). At present, in the Department of Organic Chemistry derivates of DIM are synthesised, which could be considered as potential chemotherapeutics.
Keywords:
tumour, breast cancer, chemical therapy, 3,3’-diindolylmethaneMost read articles by the same author(s)
- Aneta Affek, Maria Niemyjska, Martyna Wełpa, INDAZOLE DERIVATIVES AS ANTICANCER AGENTS , Prospects in Pharmaceutical Sciences: Vol. 15 No. 1 (2017)
- Piotr Luliński, Dorota Maciejewska, SYNTHESIS OF DOPAMINE-IMPRINTED POLYMERS AND THEORETICAL ANALYSIS OF INTERMOLECULAR INTERACTIONS IN TEMPLATE-MONOMERS , Prospects in Pharmaceutical Sciences: Vol. 6 No. 1 (2008)
- Karolina Gimpel, Piotr Luliński, Dorota Maciejewska, SELECTED SYSTEMS OPTIMIZING DRUG DELIVERY , Prospects in Pharmaceutical Sciences: Vol. 7 No. 3 (2009)
Similar Articles
- Aleksandra Kowalska, The Vitamin E: overview of history of discovery, mechanism of action, role and deficiency , Prospects in Pharmaceutical Sciences: Vol. 22 No. 3 (2024)
- Diana Dolzhko, Natalia Melnyk, Aleksandra Kruk, Sebastian Granica, Jakub Piwowarski, Traditional use of polar extracts from lavender flowers – systematic review of literature data , Prospects in Pharmaceutical Sciences: Vol. 22 No. 3 (2024)
- Iwona Lewandowska Lewandowska, Monika Zielińska-Pisklak, Łukasz Szeleszczuk, Dariusz Maciej Pisklak, Marcin Sobczak, PULMONARY HYPERTENSION — PATHOPHYSIOLOGY AND DRUGS USED IN THERAPY , Prospects in Pharmaceutical Sciences: Vol. 18 No. 2 (2020)
- Natalia Korytowska, Beata Pytlak, Mariusz Niemczyk, CHRONIC KIDNEY DISEASE AND SELECTED ASPECTS OF KIDNEY RECIPIENTS MONITORING , Prospects in Pharmaceutical Sciences: Vol. 18 No. 4 (2020)
- Grzegorz Nałęcz-Jawecki, WATER ENVIROMENT TOXICITY INVESTIGATED BY BIOASSAYS , Prospects in Pharmaceutical Sciences: Vol. 1 No. 2 (2003)
- Natalia Melnyk, Aleksandra Nyczka, Jakub P. Piwowarski, Sebastian Granica, Traditional Use of Chamomile Flowers (Matricariae flos) in Inflammatory-Associated Skin Disorders , Prospects in Pharmaceutical Sciences: Vol. 22 No. 4 (2024)
- Mayur Kadam, Nitin L. Jadhao, Jayant M. Gajbhiye, Synthesis of pyrazole and 1,3,4-oxadiazole derivatives of pharmaceutical potential , Prospects in Pharmaceutical Sciences: Vol. 22 No. 3 (2024)
- Magdalena Makarewicz, Anna Łysiak, Katarzyna Łysiak, Barbara Maziarz, Evaluation of the effectiveness of platelet-rich plasma therapy in the treatment of osteoarthritis compared to other treatment methods , Prospects in Pharmaceutical Sciences: Vol. 22 No. 4 (2024)
- Katarzyna Łysiak, Anna Łysiak, Barbara Maziarz, Paulina Przywara, Natalia Bogumiłło, Julia Ignacak, Kinga Ściurka, Mikołaj Borek, Oliwia Grzelak, Insomnia in the elderly and contemporary treatment methods , Prospects in Pharmaceutical Sciences: Vol. 22 No. 4 (2024)
- Bartłomiej Kot, Mateusz Moczulski, Agnieszka Czajkowska, Arkadiusz Kocur, Pharmacotherapy of apnea in the premature neonatological subpopulation – therapeutic opportunities, pharmacokinetic implications and recommendations for therapeutic drug monitoring , Prospects in Pharmaceutical Sciences: Vol. 22 No. 2 (2024)
You may also start an advanced similarity search for this article.
Details
References
Statistics
Authors
Citation rules
Cited by / Share
Licence
This work is licensed under a Creative Commons Attribution 4.0 International License.