Yanez-Mo M, Siljander PR, Andreu Z, Zavec AB, Borras FE, Buzas EI, Buzas K, Casal E, Cappello F, Carvalho J, Colas E, Cordeiro-da Silva A, Fais S, Falcon-Perez JM, Ghobrial IM, Giebel B, Gimona M, Graner M, Gursel I, Gursel M, Heegaard NH, Hendrix A, Kierulf P, Kokubun K, Kosanovic M, Kralj-Iglic V, Kramer-Albers EM, Laitinen S, Lasser C, Lener T, Ligeti E, Line A, Lipps G, Llorente A, Lotvall J, Mancek-Keber M, Marcilla A, Mittelbrunn M, Nazarenko I, Nolte-'t Hoen EN, Nyman TA, O'Driscoll L, Olivan M, Oliveira C, Pallinger E, Del Portillo HA, Reventos J, Rigau M, Rohde E, Sammar M, SanchezMadrid F, Santarem N, Schallmoser K, Ostenfeld MS, Stoorvogel W, Stukelj R, Van der Grein SG, Vasconcelos MH, Wauben MH, De Wever O, Biological properties of extracellular vesicles and their physiological functions, J Extracell Vesicles, 2015, 4, 27066. DOI: https://doi.org/10.3402/jev.v4.27066

Huebner AR, Somparn P, Benjachat T, Leelahavanichkul A, Avihingsanon Y, Fenton RA, Pisitkun T, Exosomes in urine biomarker discovery, Adv Exp Med Biol, 2015, 845, 43-58. DOI: https://doi.org/10.1007/978-94-017-9523-4_5

Nonaka T, Wong DTW, Saliva-exosomics in cancer: molecular characterization of cancer-derived exosomes in saliva, Enzymes, 2017, 42, 125-151. DOI: https://doi.org/10.1016/bs.enz.2017.08.002

Koh YQ, Peiris HN, Vaswani K, Meier S, Burke CR, Macdonald KA, Roche JR, Almughlliq F, Arachchige BJ, Reed S, Mitchell MD, Characterization of exosomes from body fluids of dairy cows, J Anim Sci, 2017, 95, 3893-3904. DOI: https://doi.org/10.2527/jas.2017.1727

Wolf P, The nature and significance of platelet products in human plasma, Br J Haematol, 1967, 13, 269-288. DOI: https://doi.org/10.1111/j.1365-2141.1967.tb08741.x

Pan BT, Teng K, Wu C, Adam M, Johnstone RM, Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes, J Cell Biol, 1985, 101, 942-948. DOI: https://doi.org/10.1083/jcb.101.3.942

Zhang J, Li S, Li L, Li M, Guo C, Yao J, Mi S, Exosome and exosomal microRNA: trafficking, sorting, and function, Genomics Proteomics Bioinformatics, 2015, 13, 17-24. DOI: https://doi.org/10.1016/j.gpb.2015.02.001

Johnstone RM, The Jeanne Manery-Fisher Memorial Lecture 1991. Maturation of reticulocytes: formation of exosomes as a mechanism for shedding membrane proteins, Biochem Cell Biol, 1992, 70, 179- 190. DOI: https://doi.org/10.1139/o92-028

Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Bedina Zavec A, Benmoussa A, Berardi AC, Bergese P, Bielska E, Blenkiron C, BobisWozowicz S, Boilard E, Boireau W, Bongiovanni A, Borràs FE, Bosch

S, Boulanger CM, Breakefield X, Breglio AM, Brennan M, Brigstock DR, Brisson A, Broekman ML, Bromberg JF, Bryl-Górecka P, Buch S, Buck AH, Burger D, Busatto S, Buschmann D, Bussolati B, Buzás EI, Byrd JB, Camussi G, Carter DR, Caruso S, Chamley LW, Chang YT, Chen C, Chen S, Cheng L, Chin AR, Clayton A, Clerici SP, Cocks A, Cocucci E, Coffey RJ, Cordeiro-da-Silva A, Couch Y, Coumans FA, Coyle B, Crescitelli R, Criado MF, D'Souza-Schorey C, Das S, Datta Chaudhuri A, de Candia P, De Santana EF, De Wever O, Del Portillo HA, Demaret T, Deville S, Devitt A, Dhondt B, Di Vizio D, Dieterich LC, Dolo V, Dominguez Rubio AP, Dominici M, Dourado MR, Driedonks TA, Duarte FV, Duncan HM, Eichenberger RM, Ekström K, El Andaloussi S, Elie-Caille C, Erdbrügger U, Falcón-Pérez JM, Fatima F, Fish JE, Flores-Bellver M, Försönits A, Frelet-Barrand A, Fricke F, Fuhrmann G, Gabrielsson S, Gámez-Valero A, Gardiner C, Gärtner K, Gaudin R, Gho YS, Giebel B, Gilbert C, Gimona M, Giusti I, Goberdhan DC, Görgens A, Gorski SM, Greening DW, Gross JC, Gualerzi A, Gupta GN, Gustafson D, Handberg A, Haraszti RA, Harrison P, Hegyesi H, Hendrix A, Hill AF, Hochberg FH, Hoffmann KF, Holder B, Holthofer H, Hosseinkhani B, Hu G, Huang Y, Huber V, Hunt S, Ibrahim AG, Ikezu T, Inal JM, Isin M, Ivanova A, Jackson HK, Jacobsen S, Jay SM, Jayachandran M, Jenster G, Jiang L, Johnson SM, Jones JC, Jong A, Jovanovic-Talisman T, Jung S, Kalluri R, Kano SI, Kaur S, Kawamura Y, Keller ET, Khamari D, Khomyakova E, Khvorova A, Kierulf P, Kim KP, Kislinger T, Klingeborn M, Klinke DJ, Kornek M, Kosanović MM, Kovács Á, Krämer-Albers EM, Krasemann S, Krause M, Kurochkin IV, Kusuma GD, Kuypers S, Laitinen S, Langevin SM, Languino LR, Lannigan J, Lässer C, Laurent LC, Lavieu G, Lázaro-Ibáñez E, Le Lay S, Lee MS, Lee YXF, Lemos DS, Lenassi M, Leszczynska A, Li IT, Liao K, Libregts SF, Ligeti E, Lim R, Lim SK, Linē A, Linnemannstöns K, Llorente A, Lombard CA, Lorenowicz MJ, Lörincz Á, Lötvall J, Lovett J, Lowry MC, Loyer X, Lu Q, Lukomska B, Lunavat TR, Maas SL, Malhi H, Marcilla A, Mariani J, Mariscal J, Martens-Uzunova ES, Martin-Jaular L, Martinez MC, Martins VR, Mathieu M, Mathivanan S, Maugeri M, McGinnis LK, McVey MJ, Meckes DG, Meehan KL, Mertens I, Minciacchi VR, Möller A, Møller Jørgensen M, Morales-Kastresana A, Morhayim J, Mullier F, Muraca M, Musante L, Mussack V, Muth DC, Myburgh KH, Najrana T, Nawaz M, Nazarenko I, Nejsum P, Neri C, Neri T, Nieuwland R, Nimrichter L, Nolan JP, Nolte-'t Hoen EN, Noren Hooten N, O'Driscoll L, O'Grady T, O'Loghlen A, Ochiya T, Olivier M, Ortiz A, Ortiz LA, Osteikoetxea X, Østergaard O, Ostrowski M, Park J, Pegtel DM, Peinado H, Perut F, Pfaffl MW, Phinney DG, Pieters BC, Pink RC, Pisetsky DS, Pogge von Strandmann E, Polakovicova I, Poon IK, Powell BH, Prada I, Pulliam L, Quesenberry P, Radeghieri A, Raffai RL, Raimondo S, Rak J, Ramirez MI, Raposo G, Rayyan MS, Regev-Rudzki N, Ricklefs FL, Robbins PD, Roberts DD, Rodrigues SC, Rohde, Rome S, Rouschop KM, Rughetti A, Russell AE, Saá P, Sahoo S, SalasHuenuleo E, Sánchez C, Saugstad J, Saul MJ, Schiffelers RM, Schneider R, Schøyen TH, Scott A, Shahaj E, Sharma S, Shatnyeva O, Shekari F, Shelke GV, Shetty AK, Shiba K, Siljander PR, Silva AM, Skowronek A, Snyder OL, Soares RP, Sódar BW, Soekmadji C, Sotillo J, Stahl PD, Stoorvogel W, Stott SL, Strasser EF, Swift S, Tahara H, Tewari M, Timms K, Tiwari S, Tixeira R, Tkach M, Toh WS, Tomasini R, Torrecilhas AC, Tosar JP, Toxavidis V, Urbanelli L, Vader P, van Balkom BW, van der Grein SG, Van Deun J, van Herwijnen MJ, Van Keuren-Jensen K, van Niel G, van Royen ME, van Wijnen AJ, Vasconcelos MH, Vechetti IJ, Veit TD, Vella LJ, Velot É, Verweij FJ, Vestad B, Viñas JL, Visnovitz T, Vukman KV, Wahlgren J, Watson DC, Wauben MH, Weaver A, Webber JP, Weber V, Wehman AM, Weiss DJ, Welsh JA, Wendt S, Wheelock AM, Wiener Z, Witte L, Wolfram J, Xagorari A, Xander P, Xu J, Yan X, Yáñez-Mó M, Yin H, Yuana Y, Zappulli V, Zarubova J, Žėkas V, Zhang JY, Zhao Z, Zheng L, Zheutlin AR, Zickler AM, Zimmermann P, Zivkovic AM, Zocco D, Zuba-Surma EK, Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MIS V2014 guidelines, J Extracell Vesicles, 2018, 7, 1535750. DOI: https://doi.org/10.1080/20013078.2018.1535750

Hessvik NP, Llorente A, Current knowledge on exosome biogenesis and release, Cell Mol Life Sci, 2018, 75, 193-208. DOI: https://doi.org/10.1007/s00018-017-2595-9

Wójtowicz A, Baj-Krzyworzeka M, Baran J, Characterization and biological role of extracellular vesicles, Postepy hig med dosw (Online), 2014, 68, 1421-1432. DOI: https://doi.org/10.5604/17322693.1130655

Ambudkar SV, Sauna ZE, Gottesman MM, Szakacs G, A novel way tospread drug resistance in tumor cells: functional intercellular transfer of P-glycoprotein (ABCB1), Trends Pharmacol Sci, 2005, 26, 385-387. DOI: https://doi.org/10.1016/j.tips.2005.06.001

Filipazzi P, Burdek M, Villa A, Rivoltini L, Huber V, Recent advances on the role of tumor exosomes in immunosuppression and disease progression, Semin Cancer Biol, 2012, 22, 342-349. DOI: https://doi.org/10.1016/j.semcancer.2012.02.005

Safaei R, Larson BJ, Cheng TC, Gibson MA, Otani S, Naerdemann W, Howell SB, Abnormal lysosomal trafficking and enhanced exosomal export of cisplatin in drug-resistant human ovarian carcinoma cells, Mol Cancer Ther, 2005, 4, 1595-1604. DOI: https://doi.org/10.1158/1535-7163.MCT-05-0102

Shedden K, Xie XT, Chandaroy P, Chang YT, Rosania GR, Expulsion of small molecules in vesicles shed by cancer cells: association with gene expression and chemosensitivity profiles, Cancer Res, 2003, 63, 4331-4337.

Wang Y, Zhang D, Wu K, Zhao Q, Nie Y, Fan D, Long noncoding RNA MRUL promotes ABCB1 expression in multidrug-resistant gastric cancer cell sublines, Mol Cell Biol, 2014, 34, 3182-3193. DOI: https://doi.org/10.1128/MCB.01580-13

Tkach M, Théry C, Communication by extracellular vesicles: where we are and where we need to go, Cell, 2016, 164, 1226-1232. DOI: https://doi.org/10.1016/j.cell.2016.01.043

Siegel RL, Miller KD, Fedewa SA, Ahnen DJ, Meester RGS, Barzi A, Jemal A, Colorectal cancer statistics, 2017, CA Cancer J Clin, 2017, 67, 177-193. DOI: https://doi.org/10.3322/caac.21395

Li Y, Gao Y, Gong C, Wang Z, Xia Q, Gu F, Hu C, Zhang L, Guo H, Gao S, A33 antibody-functionalized exosomes for targeted deliveryof doxorubicin against colorectal cancer, Nanomedicine, 2018, 14, 1973-1985. DOI: https://doi.org/10.1016/j.nano.2018.05.020

Baptistella AR, Salles Dias MV, Aguiar S, Begnami MD, Martins VR, Heterogeneous expression of A33 in colorectal cancer: possible explanation for A33 antibody treatment failure, Anticancer Drugs, 2016, 27, 734-737. DOI: https://doi.org/10.1097/CAD.0000000000000379

Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A, Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries, CA Cancer J Clin, 2018. DOI: https://doi.org/10.3322/caac.21492

Fu H, Yang H, Zhang X, Wang B, Mao J, Li X, Wang M, Zhang B, Sun Z, Qian H, Xu W, Exosomal TRIM3 is a novel marker and therapy target for gastric cancer, J Exp Clin Cancer Res, 2018, 37, 162. DOI: https://doi.org/10.1186/s13046-018-0825-0

Hatakeyama S, TRIM family proteins: roles in autophagy, immunity, and carcinogenesis, Trends Biochem Sci, 2017, 42, 297-311. DOI: https://doi.org/10.1016/j.tibs.2017.01.002

Watanabe M, Hatakeyama S, TRIM proteins and diseases, J Biochem, 2017, 161, 135-144. DOI: https://doi.org/10.1093/jb/mvw087

Chen W, Lu C, Hong J, TRIM15 exerts anti-tumor effects through suppressing cancer cell invasion in gastric adenocarcinoma, Med Sci Monit, 2018, 24, 8033-8041. DOI: https://doi.org/10.12659/MSM.911142

Gonzalez-Angulo AM, Morales-Vasquez F, Hortobagyi GN, Overview of resistance to systemic therapy in patients with breast cancer, Adv Exp Med Biol, 2007, 608, 1-22. DOI: https://doi.org/10.1007/978-0-387-74039-3_1

Vu T, Claret FX, Trastuzumab: updated mechanisms of action and resistance in breast cancer, Front Oncol, 2012, 2, 62. DOI: https://doi.org/10.3389/fonc.2012.00062

Donepudi MS, Kondapalli K, Amos SJ, Venkanteshan P, Breast cancer statistics and markers, J Cancer Res Ther, 2014, 10, 506-511.

Consortium EP, An integrated encyclopedia of DNA elements in the human genome, Nature, 2012, 489, 57-74. DOI: https://doi.org/10.1038/nature11247

Li P, Zhang X, Wang H, Wang L, Liu T, Du L, Yang Y, Wang C, MALAT1 is associated with poor response to oxaliplatin-based chemotherapy in colorectal cancer patients and promotes chemoresistance through EZH2, Mol Cancer Ther, 2017, 16, 739-751. DOI: https://doi.org/10.1158/1535-7163.MCT-16-0591

Schmitt AM, Chang HY, Long noncoding RNAs in cancer pathways, Cancer Cell, 2016, 29, 452-463. DOI: https://doi.org/10.1016/j.ccell.2016.03.010

Dong H, Wang W, Chen R, Zhang Y, Zou K, Ye M, He X, Zhang F, Han J, Exosome-mediated transfer of lncRNA‑SNHG14 promotes trastuzumab chemoresistance in breast cancer, Int J Oncol, 2018, DOI: https://doi.org/10.3892/ijo.2018.4467

, 1013-1026.

Dong H, Wang W, Mo S, Liu Q, Chen X, Chen R, Zhang Y, Zou K, Ye M, He X, Zhang F, Han J, Hu J, Long non-coding RNA SNHG14 induces trastuzumab resistance of breast cancer via regulating PABPC1 expression through H3K27 acetylation, J Cell Mol Med, 2018, 22, 4935-4947. DOI: https://doi.org/10.1111/jcmm.13758

Zhang X, Zhao P, Wang C, Xin B, SNHG14 enhances gemcitabine resistance by sponging miR-101 to stimulate cell autophagy in pancreatic cancer, Biochem Biophys Res Commun, 2019, 9, 508-514. DOI: https://doi.org/10.1016/j.bbrc.2019.01.109

Zhang Z, Wang Y, Zhang W, Li J, Liu W, Lu W, Long non-coding RNA SNHG14 exerts oncogenic functions in non-small cell lung cancer through acting as an miR-340 sponge, Biosci Rep, 2019, 3, 39. DOI: https://doi.org/10.1042/BSR20180941

Didkowska J, Wojciechowska U, Mańczuk M, Łobaszewski J, Lung cancer epidemiology: contemporary and future challenges worldwide, Ann Transl Med, 2016, 4, 150. DOI: https://doi.org/10.21037/atm.2016.03.11

Kutkowska J, Porębska I, Rapak A, Non-small cell lung cancer - mutations, targeted and combination therapy, Postepy Hig Med Dosw (Online), 2017, 71, 431-445. DOI: https://doi.org/10.5604/01.3001.0010.3826

Jing C, Cao H, Qin X, Yu S, Wu J, Wang Z, Ma R, Feng J, Exosomemediated gefitinib resistance in lung cancer HCC827 cells via delivery of miR-21, Oncol Lett, 2018, 15, 9811-9817. DOI: https://doi.org/10.3892/ol.2018.8604

Ziyan W, Yang L, MicroRNA-21 regulates the sensitivity to cisplatin in a human osteosarcoma cell line, Ir J Med Sci, 2016, 185, 85-91. DOI: https://doi.org/10.1007/s11845-014-1225-x

Yu X, Zhao X, Zhang J, Li Y, Sheng P, Ma C, Zhang L, Hao X, Zheng X, Xing Y, Qiao H, Qu L, Zhu D, Dacomitinib, a new pan-EGFR inhibitor, is effective in attenuating pulmonary vascular remodeling and pulmonary hypertension, Eur J Pharmacol, 2019, 5, 850-897. DOI: https://doi.org/10.1016/j.ejphar.2019.02.008

Yamaguchi O, Kaira K, Mouri A, Shiono A, Hashimoto K, Miura Y, Nishihara F, Murayama Y, Kobayashi K, Kagamu H, Re-challenge of afatinib after 1st generation EGFR-TKI failure in patients with previously treated non-small cell lung cancer harboring EGFR mutation, Cancer Chemother Pharmacol, 2019, 83(5), 817-825. DOI: https://doi.org/10.1007/s00280-019-03790-w

Ko B, Halmos B, Capmatinib and gefitinib combination therapy: will EGFR-mutated MET-dysregulated NSCLC "capitulate"?, Transl Lung Cancer Res, 2018, 7, S321-S325. DOI: https://doi.org/10.21037/tlcr.2018.12.05

Didkowska J WU, Zatoński W, Prognozy zachorowalności i umieralności na nowotwory złośliwe w Polsce do 2025 roku. 2009, Warszawa: Centrum Onkologii. Instytut im. Marii Skłodowskiej-Curie.