Published : 2024-05-10

Some biological activities and element levels of Lycoperdon pratense

Ali İmran Korkmaz

Celal Bal

Tetiana Krupodorova

Mehmet Ali Yüzbaşıoğlu

Beste Gizem Özbey Sarıdoğan

Mustafa Sevindik

Abstract

Mushrooms are natural products with many biological activities. In this study, antioxidant, antimicrobial, anticholinesterase activities and element levels of Lycoperdon pratense Pers. were determined. In this context, the mushroom was extracted with ethanol in a soxhlet device. Antioxidant potential was determined using Rel assay kits. Antimicrobial activity was determined using the agar dilution method. Antialzheimer activity was determined by acetyl- (AChE) and butyrylcholinesterase (BChE) potentials. The levels of elements accumulated in the mushroom were scanned using the wet digestion method. As a result of the analysis, the TAS value of the mushroom was measured as 2.589 ± 0.118 mmol Trolox equiv./L, the TOS value was 10.360 ± 0.197 µmol H2O2 equiv./L and the OSI value was 0.401±0.013. The mushroom extract was found to have high activity against bacteria. It was determined that the extract had an effect against microorganisms at concentrations between 50-400 μg/mL. It was determined that the anti-AChE IC50 value of the mushroom extract was 14.48 ± 0.80 μg/mL and the anti-BChE IC50 value was 23.10±1.21 μg/mL. It is also thought that it can be used as an indicator in terms of element levels within the mushroom. As a result, it was determined that the mushroom has antioxidant, antimicrobial and antiallergic potential.

Keywords:

Antimicrobial, antioxidant, Lycoperdon, Medicinal plants, antialzheimer


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Korkmaz, A. İmran, Bal, C., Krupodorova, T., Yüzbaşıoğlu, M. A., Özbey Sarıdoğan, B. G., & Sevindik, M. (2024). Some biological activities and element levels of Lycoperdon pratense. Prospects in Pharmaceutical Sciences, 22(2), 39–44. https://doi.org/10.56782/pps.189

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Editorial Team
Stefana Banacha 1
02-097 Warsaw, Poland
biuletynfarmacji@wum.edu.pl
Publisher:
Medical University of Warsaw
ul. Żwirki i Wigury 61
02-091 Warszawa

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