KOMPLEKSY MIEDZI(II) ZASAD SCHIFFA - NOWE ZWIĄZKI O AKTYWNOŚCI PRZECIWDROBNOUSTROJOWEJ

Elżbieta Hejchman; Dominik Lewandowski

doi:10.56782/pps.81

Published : 2017-08-21

Vol. 15 No. 9 (2017)

SCHIFF BASE COPPER (II) COMPLEXES - NOVEL COMPOUNDS WITH ANTIMICROBIAL ACTIVITY

Elżbieta Hejchman

Dominik Lewandowski

DOI: https://doi.org/10.56782/pps.81

Abstract

Schiff bases are prepared via condensation of primary amines and aldehydes or ketones. The products are stable and exhibit antimicrobial, antiproliferative, as well as anti-inflammatory activity. Using them as ligands in the preparation of copper (II) complexes results in an increase of their biological activity. This paper reviews the latest literature reports concerning the antimicrobial activity of Schiff bases: derivatives of salicylaldehyde and 7-hydroxycoumarin, 8-substituted with a formyl or an acetyl group. We also describe the biological activity of their copper(II) complexes.

Keywords:

salicylaldehyde, coumarin, Schiff base, copper(II) complex, antimicrobial activity

Similar Articles

Magdalena Bielińska, Grzegorz Nałęcz-Jawecki, PHARMACEUTICALS IN THE ENVIRONMENT. I: EVALUATION OF TOXICITY OF THREE FLUOROQUINOLONES TO DUCKWEED LEMNA MINOR , Prospects in Pharmaceutical Sciences: Vol. 7 No. 4 (2009)
Dominika Łacheta, Wioletta Olejarz, OCHRONNA ROLA KWASU α-LIPONOWEGO W MIAŻDŻYCY I CHOROBACH SERCOWO-NACZYNIOWYCH , Prospects in Pharmaceutical Sciences: Vol. 17 No. 8 (2019)
Mustafa Sevindik, Celal Bal, Emre Cem Eraslan, İmran Uysal, Falah Saleh Mohammed, Medicinal mushrooms: a comprehensive study on their antiviral potential , Prospects in Pharmaceutical Sciences: Vol. 21 No. 2 (2023)
Joanna J. Sajkowska, Katarzyna Paradowska, MULTIPLE ACTIVITIES OF VITAMIN D , Prospects in Pharmaceutical Sciences: Vol. 12 No. 1 (2014)
Zofia Suchocka, OBESITY - REASONS AND TREATMENT , Prospects in Pharmaceutical Sciences: Vol. 1 No. 1 (2003)
Dominika Winiarz, Kamila Domańska, Kinga Paluch, Dorota Dorota Skrajnowska, PROBIOTICS AND HEALTH - TODAY AND TOMORROW , Prospects in Pharmaceutical Sciences: Vol. 15 No. 10 (2017)
Bartosz Kózka, Anna Kowalkowska, BENZIMIDAZOLE DERIVATES WITH BIOLOGICAL ACTIVITY , Prospects in Pharmaceutical Sciences: Vol. 15 No. 3 (2017)
Paulina Wilczyńska, Barbara Lisowska-Myjak, ROLA AMINOPEPTYDAZ ŁOŻYSKOWYCH W PRZEBIEGU CIĄŻY , Prospects in Pharmaceutical Sciences: Vol. 17 No. 1 (2019)
Anna Babis, USABILITY OF THE FRUITS OF ROSA SPINOSISSIMA AND ROSA HYBRIDA TO THE PRODUCTION OF TURBID MULTIVITAMIN JUICES , Prospects in Pharmaceutical Sciences: Vol. 2 No. 3 (2004)
Falah Saleh Mohammed, Imran Uysal, Hasan Hüseyin Yaz, Mustafa Sevindik, Papaver species: usage areas, essential oil, nutrient and elements contents, biological activities , Prospects in Pharmaceutical Sciences: Vol. 21 No. 4 (2023)

<< < 1 2 3 4 5 6 7 8 > >>

You may also start an advanced similarity search for this article.

Details

References

Statistics

Authors

Download files

PDF (Język Polski)

Citation rules

Hejchman, E., & Lewandowski, D. (2017). SCHIFF BASE COPPER (II) COMPLEXES - NOVEL COMPOUNDS WITH ANTIMICROBIAL ACTIVITY. Prospects in Pharmaceutical Sciences, 15(9), 80–85. https://doi.org/10.56782/pps.81

Altmetric indicators

Cited by / Share

Licence

This work is licensed under a Creative Commons Attribution 4.0 International License.

References

Przybylski P., Buczyński A., Brzeziński B., Schroeder G., Aktywność biologiczna zasad Schiffa i innych aza-pochodnych fenoli. Schroeder W.G. (red.): Materiały supramolekularne. Poznań: Betagraf P.U.H., 2008, 89-133.

Joseyphus R. S. and Nair M. S., Antibacterial and Antifungal Studies on Some Schiff Base Complexes of Zinc(II), Mycobiology, 2008, 36 (2), 93-98. DOI: https://doi.org/10.4489/MYCO.2008.36.2.093

Rani A., Kumar M., Khare R. and Tuli H. S., Schiff bases as an antimicrobial agent: A review. Journal of Biological and Chemical Sciences (JBCS), 2015, 2(1) 62-91.

https://dailymed.nlm.nih.gov/ dailymed/drugInfo, 21.08.2017.

https://www.accessdata.fda.gov /scripts/cder/daf/index.cfm?event=overview. process&ApplNo=019456. 21.08.2017.

da Silva M. C., da Silva D. L., Modolo L. V., Alves R. B., de Resende M. A., Martins C. V. B., de Fatima A., Schiff bases: A short review of their antimicrobial activities, Journal of Advanced Research, 2011, (2), 1–8. DOI: https://doi.org/10.1016/j.jare.2010.05.004

de Souza A. O., Galetti F. C. S., and Silva C. L., Bicalho B., Parma M. M., Fonseca S. F. and Marsaioli A. J., Trindade A. C. L. B., Rossimíriam P., Gil F, Bezerra F. S., Andrade-Neto M. and de Oliveira M. C. F., Antimycobacterial And Cytotoxicity Activity Of Synthetic And Natural Compounds, Quim. Nova, 2007, 30 (7), 1563-1566. DOI: https://doi.org/10.1590/S0100-40422007000700012

Shi L, Ge H-M., Tan S-H., Li H-Qi., Song Y-C., Zhu H-L., Tan R-Xi., Synthesis and antimicrobial activities of Schiff bases derived from 5-chloro-salicylaldehyde, European Journal of Medicinal Chemistry 2007, 42(4), 558-564. DOI: https://doi.org/10.1016/j.ejmech.2006.11.010

Tantaru G., Popescu M-C., Bilda V., Poiata A., Lisa G. and Vasile C., Spectroscopic, thermal and antimicrobial properties of the copper(II) complex of Schiff base derived from 2-(salicylidene) aminopyridine, Appl. Organometal. Chem. 2012, 26, 356–361. DOI: https://doi.org/10.1002/aoc.2872

Hejchman E., Tomczyk M., Związki kompleksowe miedzi(II) jako potencjalne leki przeciwnowotworowe. Farmacja Polska. 2015, 71(12), 750-757.

Joshi K. R., Rojivadiya A. J., and Pandya J. H.. Synthesis and Spectroscopic and Antimicrobial Studies of Schiff Base Metal Complexes Derived from 2-Hydroxy-3-methoxy-5-nitrobenzaldehyde. Hindawi Publishing Corporation, International Journal of Inorganic Chemistry. 2014, Article ID 817412, 1-8, http://dx.doi.org/10.1155/ 2014/817412, 21.08.2017. DOI: https://doi.org/10.1155/2014/817412

Thakur A., Singla R., Jaitak V. Coumarins as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies. Eur. J. Med. Chem., 2015, 101, 476-495. DOI: https://doi.org/10.1016/j.ejmech.2015.07.010

Singh D., Pathak D. P. and Anjali, Coumarins: An Overview Of Medicinal Chemistry. Potential For New Drug Molecules. International Journal of Pharmaceutical Sciences and Research. 2016, 7(2), 482-504.

Ostrowska K., Hejchman E., Grzeszczuk D., Kruk N.. Leki kumarynowe. Farmacja Polska. 2013, 69(5), 303-310.

Creaven B. S,, Devereux M., Karcz D., Kellett A., McCann M., Noble A., Walsh M., Copper(II) complexes of coumarin-derived Schiff bases and their anti-Candida activity. Journal of Inorganic Biochemistry 2009, 103, 1196-1203. DOI: https://doi.org/10.1016/j.jinorgbio.2009.05.017

Bagihalli G. B., Avaji P. G, Patil S. A., Badami P. S., Synthesis, spectral characterization, in vitro antibacterial, antifungal and cytotoxic activities of Co(II), Ni(II) and Cu(II) complexes with 1,2,4-triazole Schiff bases, Eur. J. Med. Chem, 2008, 43, 2639-2649. DOI: https://doi.org/10.1016/j.ejmech.2008.02.013

Bagihalli G. .B., Badami P. S. & Patil S. A., Synthesis, spectral characterization and in vitro biological studies of Co(II), Ni(II) and Cu(II) complexes with 1,2,4-triazole Schiff bases Journal of Enzyme Inhibition and Medicinal Chemistry, 2009, 24(2), 381-394. DOI: https://doi.org/10.1080/14756360802187901

Patil S. A., Unki S. N., Badami P. S., Synthesis, characterization, biological and thermal behavior of Co(II), Ni(II) and Cu(II) complexes with Schiff bases having coumarin moieties. J. Therm. Anal. Calorim., 2013, 111, 1281-1289. DOI: https://doi.org/10.1007/s10973-012-2293-7

Prabhakara C. T., Patil S. A., Toragalmath S. S., Kinnal S. M., Badami P. S., Synthesis, characterization and biological approach of metal chelates of some first row transition metal ions with halogenated bidentate coumarin Schiff bases containing N and O donor atoms, Journal of Photochemistry & Photobiology, B: Biology , 2016, 157, 1-14. DOI: https://doi.org/10.1016/j.jphotobiol.2016.02.004

Phaniband M. A., Dhumwad S. D., Pattan S. R., Synthesis, characterization, antimicrobial, and DNA cleavage studies of metal complexes of coumarin Schiff bases, Med. Chem. Res., 2011, 20, 493-502. DOI: https://doi.org/10.1007/s00044-010-9343-0

Patil S. A., Unki S. N., Badami P. S., In vitro antibacterial, antifungal, and DNA cleavage studies of coumarin Schiff bases and their metal complexes: synthesis and spectral characterization. Med. Chem. Res., 2012, 21, 4017-4027. DOI: https://doi.org/10.1007/s00044-011-9932-6

Prabhakara C. T., Patil S. A., Kulkarni A. D., Naik V. H., Manjunatha M., Kinnal S. M., Badami P. S., Synthesis, spectral, thermal, fluorescence, antimicrobial, anthelmintic and DNA cleavage studies of mononuclear metal chelates of bi-dentate 2H-chromene-2-one Schiff base. Journal of Photochemistry and Photobiology B: Biology 2015, 148, 322-332. DOI: https://doi.org/10.1016/j.jphotobiol.2015.03.033

Sawant S. S., Pavar V. ,Janrao S., Yamgar R. S. and Nivid Y., Synthesis And Characterization Of Transition Metal Complexes Of Novel Schiff Base 8-[(Z)-[(3-N-Methylamino)Propyl]Imino)Methyl]-7-Hydroxy-4-Methyl-2H-Chromen-2-One] [NMAPIMHC] And Their Biological Activities, International Journal of Research in Pharmacy and Chemistry, 2013, 3(3), 636-644, www.ijrpc.com.

Elżbieta Hejchman

ehejchman@wum.edu.pl

Affiliation:

Zakład Chemii Organicznej, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej, Warszawski Uniwersytet Medyczny, ul. Banacha 1, 02-097 Warszawa Poland

Dominik Lewandowski

Affiliation:

Zakład Chemii Organicznej, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej, Warszawski Uniwersytet Medyczny, ul. Banacha 1, 02-097 Warszawa Poland