A review: nutrition and oral-dental health, phytochemical content, biological activity of Salvadora persica (Miswak)

Seda Sultan Sağır; Baturay Sapancı; Imran Uysal; Mustafa Sevindik

doi:10.56782/pps.177

Data publikacji : 2024-05-08

Tom 22 Nr 2 (2024)

A review: nutrition and oral-dental health, phytochemical content, biological activity of Salvadora persica (Miswak)

Seda Sultan Sağır

Baturay Sapancı

Imran Uysal

Mustafa Sevindik

DOI: https://doi.org/10.56782/pps.177

Abstrakt

Plants have been widely used by humans since ancient times. They serve different purposes, especially shelter, heating, nutrition, war, equipment and medicine. Nowadays, they are widely used especially in the fight against diseases. In this context, in this study, the biological activities and health effects of Salvadora persica L. reported in the literature were compiled. S. persica is known by names such as miswak, koyoji, qesam, qisa and mastic. It is a multi-branched shrub or small tree that is two to three meters tall and has edible fruit. As a result of literature research, it has been seen that the plant has purposes such as health care and nutrition source. In addition, it has been shown in the literature that it has biological activities such as antioxidant, antimicrobial, anthelmintic, cytotoxic, anti-inflammatory and antidepressant activity. The most common and highly abundant compounds in the root, twigs, and leaves of S. persica were found to be benzyl isothiocyanate, benzyl nitrile, 1,8-cineol, butylated hydroxytoluene, isothiocyanatomethyl-benzene, and (2E)-hexenal. As a result, it is thought that S. persica can be used as a natural protective agent in terms of both its usage areas and biological activities.

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Sağır, S. S., Sapancı, B., Uysal, I., & Sevindik, M. (2024). A review: nutrition and oral-dental health, phytochemical content, biological activity of Salvadora persica (Miswak). Prospects in Pharmaceutical Sciences, 22(2), 18–25. https://doi.org/10.56782/pps.177

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Bibliografia

Sevindik, M.; Mohammed, F. S.; Uysal, I. Autism: plants with neuro-psychopharmacotherapeutic potential. Prospects Pharm. Sci., 2023, 21(3), 38-48. https://doi.org/10.56782/pps.143 DOI: https://doi.org/10.56782/pps.143

Mohammed, F. S.; Günal, S.; Şabik, A. E.; Akgül, H.; Sevindik, M. Antioxidant and Antimicrobial activity of Scorzonera papposa collected from Iraq and Turkey. KSU J. Agric. Nat., 2020, 23(5), 1114-1118.

DOI: 10.18016/ksutarimdoga.vi.699457 DOI: https://doi.org/10.18016/ksutarimdoga.vi.699457

Mohammed, F. S.; Karakaş, M.; Akgül, H.; Sevindik, M. Medicinal properties of Allium calocephalum collected from Gara Mountain (Iraq). Fresen. Environ. Bull., 2019, 28(10), 7419-7426.

Mohammed, F. S.; Kına, E.; Uysal, I.; Sevindik, M. Total Phenolic, Flavonoid Contents, Antioxidant and Antimicrobial Activities of Hesperis pendula. Prospects Pharm. Sci., 2023, 21(2), 57-61. DOI: https://doi.org/10.56782/pps.135 DOI: https://doi.org/10.56782/pps.135

Unal, O.; Eraslan, E. C.; Uysal, I.; Mohammed, F. S.; Sevindik, M.; Akgul, H. Biological activities and phenolic contents of Rumex scutatus collected from Turkey. Fresen. Environ. Bull., 2022, 31(7), 7341-7346.

Uysal, I.; Koçer, O.; Mohammed, F. S.; Lekesiz, Ö.; Doğan, M.; Şabik, A. E.; Sevindik, E.; Gerçeker, F.Ö.; Sevindik, M. Pharmacological and nutritional properties: Genus Salvia. Adv. Pharmacol. Sci., 2023, 11(2), 140-155. http://dx.doi.org/10.13189/app.2023.110206 DOI: https://doi.org/10.13189/app.2023.110206

Aboul-Enein, B.H. The miswak (Salvadora persica L.) chewing stick: Cultural implications in oral health promotion. Saudi. J. Dent. Res., 2014, 5(1), 9-13. https://doi.org/10.1016/j.ksujds.2013.06.002 DOI: https://doi.org/10.1016/j.ksujds.2013.06.002

Odebiyi, O. O.; Sofowora, E. A. Antimicrobial alkaloids from a Nigerian chewing stick (Fagarazanthoxyloides). Planta Med., 1979, 36 (07), 204-207. DOI: https://doi.org/10.1055/s-0028-1097271

Ma'ayergi, H.A.; Ismail, S.I.; Batanouny, K.H.; Rızk, A.M. Ecological and phytochemical studies on the "miswak", Salvadora persica. Qatar Univ. Sci. Bull., 1984, 4, 37-44.

Almas K. The antimicrobial effects of seven different types of Asian chewing sticks. Odontostomatol. Trop., 2001, 24,17-20.

Aumeeruddy, M. Z.; Zengin, G.; Mahomoodally, M. F. A review of the traditional and modern uses of Salvadora persica L. (Miswak): Toothbrush tree of Prophet Muhammad. J. Ethnopharmacol., 2018, 213, 409-444. https://doi.org/10.1016/j.jep.2017.11.030 DOI: https://doi.org/10.1016/j.jep.2017.11.030

Bukar, A.; Danfillo, I. S.; Adeleke, O. A.; Ogunbodede, E. O. Traditional oral health practices among Kanuri women of Borno State, Nigeria. Odontostomatol. Trop., 2004, 27(107), 25-31.

Al-Sabawi, N. A.; Al Sheikh Abdal, A.; Taha, M. Y. The antimicrobial activity of Salvadora persica solution (miswak-siwak) as root canal irrigant (a comparativestudy). Univ. Sharjah J. Pure App. Sci., 2007, 4(3), 69-91.

Al-Bayaty, F. H.; AI-Koubaisi, A. H.; Ali, N. A. W.; Abdulla, M. A. Effect of mouth wash extracted from Salvadora persica (Miswak) on dental plaque formation: A clinical trial. J. Med. Plant Res., 2010, 4(14), 1446-1454.

Mohammed, F. S.; Uysal, I.; Yaz, H. H.; Sevindik, M. Papaver species: usage areas, essential oil, nutrient and elements contents, biological activities. Prospects Pharm. Sci., 2023, 21(4), 1-9. https://doi.org/10.56782/pps.142 DOI: https://doi.org/10.56782/pps.142

Krupodorova, T.; Sevindik, M. Antioxidant potential and some mineral contents of wild edible mushroom Ramaria stricta. AgroLife Sci. J., 2020, 9(1), 186-191.

Bal, C.; Eraslan, E. C.; Sevindik, M. Antioxidant, Antimicrobial Activities, Total Phenolic and Element Contents of Wild Edible Mushroom Bovista nigrescens. Prospects Pharm. Sci., 2023, 21(2), 37-41. https://doi.org/10.56782/pps.139 DOI: https://doi.org/10.56782/pps.139

Korkmaz, A. I.; Akgul, H.; Sevindik, M.; Selamoglu, Z. Study on determination of bioactive potentials of certain lichens. Acta Aliment., 2018, 47(1), 80-87. https://doi.org/10.1556/066.2018.47.1.10 DOI: https://doi.org/10.1556/066.2018.47.1.10

Eraslan, E. C.; Altuntas, D.; Baba, H.; Bal, C.; Akgül, H.; Akata, I.; Sevindik, M. Some biological activities and element contents of ethanol extract of wild edible mushroom Morchella esculenta. Sigma J. Eng. Nat. Sci., 2021, 39(1), 24-28.

Sevindik, M.; Akgül, H.; Bal, C.; Selamoglu, Z. Phenolic contents, oxidant/antioxidant potential and heavy metal levels in Cyclocybe cylindracea. Indian J. Pharm. Educ. Res., 2018, 52(3), 437-441. https://doi.org/10.5530/ijper.52.3.50 DOI: https://doi.org/10.5530/ijper.52.3.50

Mushtaq, W.; Baba, H.; Akata, I.; Sevindik, M. Antioxidant potential and element contents of wild edible mushroom Suillus granulatus. KSU J. Agric. Nat., 2020, 23(3), 592-595. https://doi.org/10.18016/ksutarimdoga.vi.653241 DOI: https://doi.org/10.18016/ksutarimdoga.vi.653241

Mohammed, F. S.; Kına, E.; Sevindik, M.; Doğan, M., Pehlivan, M. Antioxidant and antimicrobial activities of ethanol extract of Helianthemum salicifolium (Cistaceae). Indian J. Nat. Prod. Resour., 2021, 12(3), 459-462. https://doi.org/10.56042/ijnpr.v12i3.46635 DOI: https://doi.org/10.56042/ijnpr.v12i3.46635

Mohamed, S. A.; Khan, J. A. Antioxidant capacity of chewing stick miswak Salvadora persica. BMC Complement. Altern. Med., 2013, 13, 1-6. https://doi.org/10.1186/1472-6882-13-40 DOI: https://doi.org/10.1186/1472-6882-13-40

Gupta, A.; Verma, S.; Kushwaha, P.; Srivastava, S.; Rawat, A. Phytochemical and antioxidant studies of Salvadora persica L. stem and twig. Indian J. Pharm. Educ. Res., 2015, 49(1), 71-75. https://doi.org/10.5530/ijper.49.1.10 DOI: https://doi.org/10.5530/ijper.49.1.10

Sharma, V.; Ramawat, K. G. Salinity-induced modulation of growth and antioxidant activity in the callus cultures of miswak (Salvadora persica). 3 Biotech, 2013, 3, 11-17. https://doi.org/10.1007/s13205-012-0064-6 DOI: https://doi.org/10.1007/s13205-012-0064-6

Noumi, E.; Snoussi, M.; Trabelsi, N.; Hajlaoui, H.; Ksouri, R.; Valentin, E.; Bakhrouf, A. Antibacterial, anticandidal and antioxidant activities of Salvadora persica and Juglans regia L. extracts. J. Med. Plant Res., 2011, 5(17), 4138-4146.

Ramadan, K.; Alshamrani, S. Phytochemical analysis and antioxidant activity of Salvadora persica extracts. J. Basic Appl. Res., 2016, 2(3), 390-395. https://doi.org/10.51152

Mammad, Z.; Hsaine, S.; Djassinra, T.; Ounine, K. The antibacterial and antioxidant effect of Salvadora persica on antibiotic resistant strains. Am. J. Plant Sci. 2018, 9(7), 1478. https://doi.org/10.4236/ajps.2018.97108 DOI: https://doi.org/10.4236/ajps.2018.97108

El-Sherbiny, G. M.; Gazelly, A. M.; Sharaf, M. H.; Moghannemm, S. A.; Ismail, M. K.; El-Hawary, A. S. Exploitation of the antibacterial, antibiofilm and antioxidant activities of Salvadora persica (Miswak) extract. J. Bioresour. Bioprod., 2023, 8(1), 59-65. https://doi.org/10.1016/j.jobab.2022.11.006 DOI: https://doi.org/10.1016/j.jobab.2022.11.006

Al-Dabbagh, B.; Elhaty, I. A.; Murali, C.; Al Madhoon, A.; Amin, A. Salvadora persica (Miswak): antioxidant and promising antiangiogenic insights. Am. J. Plant Sci., 2018, 9(06), 1228. https://doi.org/10.4236/ajps.2018.96091 DOI: https://doi.org/10.4236/ajps.2018.96091

Farag, M.; Abdel-Mageed, W. M.; Basudan, O.; El-Gamal, A. Persicaline, a new antioxidant sulphur-containing imidazoline alkaloid from Salvadora persica roots. Molecules, 2018, 23(2), 483. https://doi.org/10.3390/molecules23020483 DOI: https://doi.org/10.3390/molecules23020483

Tatke, P.; Nehete, M.; Gabhe, S. Evaluation of antioxidant, antimicrobial and wound healing potential of Salvadora persica twig extracts. World J. Pharm. Res., 2017, 6, 1186-1199. http://dx.doi.org/10.19080/JCMAH.2018.07.555720 DOI: https://doi.org/10.20959/wjpr20174-8175

Saini, S. Screening of Salvadora persica leaves for antioxidant properties and total phenolic content. World J. Biol. Pharma. Health Sci., 2023, 14(3), 376-383. https://doi.org/10.30574/wjbphs.2023.14.3.0143 DOI: https://doi.org/10.30574/wjbphs.2023.14.3.0143

Ibrahim, M. M.; Sahli, A. A. A. A.; Alaraidh, I. A.; Al-Homaidan, A. A.; Mostafa, E. M.; El-Gaaly, G. A. Assessment of antioxidant activities in roots of Miswak (Salvadora persica) plants grown at two different locations in Saudi Arabia. Saudi J. Biol. Sci., 2015, 22(2), 168-175. https://doi.org/10.1016/j.sjbs.2014.11.019 DOI: https://doi.org/10.1016/j.sjbs.2014.11.019

Sevindik, M.; Bal, C.; Eraslan, E. C.; Uysal, I.; Mohammed, F. S. Medicinal mushrooms: a comprehensive study on their antiviral potential. Prospects Pharm. Sci., 2023, 21(2), 42-56. https://doi.org/10.56782/pps.141 DOI: https://doi.org/10.56782/pps.141

Mohammed, F. S.; Uysal, I.; Sevindik, M. A review on antiviral plants effective against different virus types. Prospects Pharm. Sci., 2023, 21(2), 1-21. https://doi.org/10.56782/pps.128 DOI: https://doi.org/10.56782/pps.128

Al-Bayati, F. A.; Sulaiman, K. D. In vitro antimicrobial activity of Salvadora persica L. extracts against some isolated oral pathogens in Iraq. Turkish J.Biol., 2008, 32(1), 57-62.

Khalil, M. A.; El-Sabbagh, M. S.; El Naggar, E. B.; El-Erian, R. H. Antibacterial activity of Salvadora persica against oral pathogenic bacterial isolates. Niger. J. Clin. Pract., 2019, 22(10), 1378-1387. https://doi.org/10.4103/njcp.njcp_413_14 DOI: https://doi.org/10.4103/njcp.njcp_413_14

Abhary, M.; Al-Hazmi, A. A. Antibacterial activity of Miswak (Salvadora persica L.) extracts on oral hygiene. J. Taibah Univ. Sci., 2016, 10(4), 513-520. https://doi.org/10.1016/j.jtusci.2015.09.007 DOI: https://doi.org/10.1016/j.jtusci.2015.09.007

Al-Ayed, M. S. Z.; Asaad, A. M.; Qureshi, M. A.; Attia, H. G.; AlMarrani, A. H. Antibacterial activity of Salvadora persica L. (Miswak) extracts against multidrug resistant bacterial clinical isolates. Evid. Based. Complement. Alternat. Med., 2016, Article No.: 7083964. http://dx.doi.org/10.1155/2016/7083964. DOI: https://doi.org/10.1155/2016/7083964

Siddeeqh, S.; Parida, A.; Jose, M.; Pai, V. Estimation of antimicrobial properties of aqueous and alcoholic extracts of Salvadora persica (Miswak) on oral microbial pathogens - an in vitro study. J. Clin. Diagn. Res., 2016, 10(9), 13-16. https://doi.org/10.7860/JCDR/2016/22213.8524 DOI: https://doi.org/10.7860/JCDR/2016/22213.8524

Asma, K.; Yasmine, C. In vitro antimicrobial activity of Salvadora persica and Juglans regia extracts against microbial strains from oral cavity. Biocatal. Agric. Biotechnol., 2021, 33, Art. No.: 102003. https://doi.org/10.1016/j.bcab.2021.102003 DOI: https://doi.org/10.1016/j.bcab.2021.102003

Al Bratty, M.; Makeen, H. A.; Alhazmi, H. A.; Syame, S. M.; Abdalla, A. N.; Homeida, H. E.; Khalid, A. Phytochemical, cytotoxic, and antimicrobial evaluation of the fruits of miswak plant, Salvadora persica L. J. Chem., 2020, Article ID 4521951. https://doi.org/10.1155/2020/4521951. DOI: https://doi.org/10.1155/2020/4521951

Alali, F.; Hudaib, M.; Aburjai, T.; Khairallah, K.; Al-Hadidi, N. GC-MS Analysis and Antimicrobial Activity of the Essential Oil from the Stem of the Jordanian Toothbrush Tree Salvadora persica. Pharma. Biol., 2005, 42(8), 577-580. https://doi.org/10.1080/13880200490901834 DOI: https://doi.org/10.1080/13880200490901834

Dkhil, M. A.; Thagfan, F. A.; Abdel-moniem, S. H.; Al-Shaebi, E. M.; Abdel-Gaber, R.; Al-Quraishy, S. Anthelmintic, anticoccidial and antioxidant activity of Salvadora persica root extracts. Saudi J. Biol. Sci., 2019, 26(6), 1223-1226. https://doi.org/10.1016/j.sjbs.2019.02.006 DOI: https://doi.org/10.1016/j.sjbs.2019.02.006

Hammad, H. M.; Al-Qaoud, K. M.; Hammad, M. M.; Mansi, M. A. Effect of Salvadora persica Linn root aqueous extract on oral epithelial dysplasia and oral cancer celllines. Trop. J. Pharm. Res., 2019, 18(12), 2591-2596. http://dx.doi.org/10.4314/tjpr.v18i12.19

El-Desouky, S. K.; Khemira, H.; Abdlgawad, A. M.; A new cytotoxic chromen-C-glucoside from the leaves of Salvadora persica. Int. J. Pure App. Biosci., 2017, 5(2), 277-281. http://dx.doi.org/10.18782/2320-7051.2926 DOI: https://doi.org/10.18782/2320-7051.2926

Esmaeili, S.; Hamzeloo-Moghadam, M.; Ghaffari, S.; Mosaddegh, M. Cytotoxic activity screening of some medicinal plants from south of Iran. Res. J. Pharmacogn., 2014, 1(4), 19-25.

Ibrahim, A. Y.; El-Gengaihi, S. E.; Motawea, H. M.; Sleem, A. A. Anti-inflammatory activity of Salvadora persica L. against carrageenan induced paw oedema in rat relevant to inflammatory cytokines. Not. Sci. Biol., 2011, 3(4), 22-28. https://doi.org/10.15835/nsb346378 DOI: https://doi.org/10.15835/nsb346378

Hemati, K.; Mehrzadi, S.; Bakhtiarian, A.; Motevalian, M.; Nikouei, V.; Foroohandeh, M.; Nikoui, V. Miswak sticks' extract anti-inflammatory properties in carrageenan test. Razi J. Med. Sci., 2019, 25(10), 38-45.

Ramadan, K. S.; Farid, H. E.; Almarashi, R. M. Antidepressant-like effects of aqueous extract of Salvadora persica in rat model of depression. Diabetes Metab. J., 2016, 7(8), 697. https://doi.org/10.4172/2155-6156.1000697 DOI: https://doi.org/10.4172/2155-6156.1000697

Qureshi, A. A.; Ashraf, R. Hamdi, A. Evaluation of hepatoprotective and antioxidant activity of Salvadora persica. King Khalid Univ. J. Health Sci., 2016, 1(2), 20-26. DOI: https://doi.org/10.4103/1658-743X.291741

Hooda, M. S.; Pal, R. Analgesic activity of crude hydro-alcoholic extract of Salvadora persica root. World J. Pharm. Res., 2017, 6, 895-902. https://doi.org/10.20959/wjpr201711-9614 DOI: https://doi.org/10.20959/wjpr201711-9614

Thagfan, F. A.; Dkhil, M. A.; Al-Quraishy, S. In vivo anticoccidial activity of Salvadora persica root extracts. Pakistan J. Zool., 2017, 49(1), 53-57. http://dx.doi.org/10.17582/journal.pjz/2017.49.1.53.57 DOI: https://doi.org/10.17582/journal.pjz/2017.49.1.51.55

Abd El-Ghani, A. A.; Ahmed, B. M.; Abdel-Raouf, A.; Nagwa, S. A.; Hussein, H. A. Salvadora persica as natural anti-viral agent. Egyptian J. Virol., 2013, 10, 78-88.

Kumari, A.; Parida, A. K.; Rangani, J.; Panda, A. Antioxidant activities, metabolic profiling, proximate analysis, mineral nutrient composition of Salvadora persica fruit unravel a potential functional food and a natural source of pharmaceuticals. Front. Pharmacol., 2017, 8, Art. No.: 61. https://doi.org/10.3389/fphar.2017.00061 DOI: https://doi.org/10.3389/fphar.2017.00061

Biglari, H.; Saeidi, M.; Sohrabi, Y.; Khaksefidi, R.; Rahdar, S.; Narooie, M.; Ahamadabadi, M. Persica a miracle in the protect and promote oral and dental health. Int. J. Pharm. Tech., 2016, 8(3), 17957-17967.

Javan, N.; Azrah, K.; Dehghan, Z.; Biglari, H. Oral health of Islamic teachings to the pharmaceutical industry (Case study: Salvadora persica). Islam Health J., 2014, 1(3), 23-34.

Milgrom, P. Tooth Decay may be Associated with Increased Risk of Dental Pain in 5-Year-Olds. J. Evid. Based. Dent. Pract., 2013, 13(1), 25-26. https://doi.org/10.1016/j.jebdp.2013.01.003 DOI: https://doi.org/10.1016/j.jebdp.2013.01.003

Halawany, H.S.; Abraham, N.B.; Siddiqui, Y.M.; Balto, H.A.; Jacob, V. Antimicrobial Efficacy of Salvadora persica Extracts on a Monospecies Biofilm on Orthodontic Brackets In Vitro. Oral Health Prev. Dent., 2016, 14(2),149-155. https://doi.org/10.3290/j.ohpd.a33926

Kumar, S.; Navneet, G.S.; Kumar, V. Preliminary Phytochemical Screening and Antimicrobial Activity of Salvadora persica Linn. Extracts against Oral Pathogens Fungal Genom. Biol., 2016, 7(131), Art. No: 2. http://dx.doi.org/10.4172/2165-8056.1000131 DOI: https://doi.org/10.4172/2165-8056.1000131

Beshah, F.; Hunde, Y.; Getachew, M.; Bachheti, R. K.; Husen, A.; Bachheti, A. Role of Traditional Chewing Sticks in Oral Hygiene and Other Benefits. Non-Timber Forest Products: Food, Healthcare and Industrial Applications, 2021, 39-73. http://dx.doi.org/10.1007/978-3-030-73077-2_3 DOI: https://doi.org/10.1007/978-3-030-73077-2_3

Ahmad, H.; Rajagopal, K. Biological activities of Salvadora persica L. Meswak). Med. Aromat. Plants, 2013, 2(4), 1-5. http://dx.doi.org/10.4172/2167-0412.1000129 DOI: https://doi.org/10.4172/2167-0412.1000129

Bader, A.; Flamini, G.; Cioni, P. L.; Morelli, I. The composition of the root oil of Salvadora persica L. J. Essent. Oil Res., 2002, 14(2), 128-129. https://doi.org/10.1080/10412905.2002.9699795 DOI: https://doi.org/10.1080/10412905.2002.9699795

Sofrata, A.; Santangelo, E. M.; Azeem, M.; Borg-Karlson, A. K.; Gustafsson, A.; Pütsep, K. Benzyl isothiocyanate, a major component from the roots of Salvadora persica is highly active against Gram-negative bacteria. PloS one, 2011, 6(8), Art. No: e23045. https://doi.org/10.1371/journal.pone.0023045 DOI: https://doi.org/10.1371/journal.pone.0023045

Albabtain, R.; Azeem, M.; Wondimu, Z.; Lindberg, T.; Borg-Karlson, A. K.; Gustafsson, A. Investigations of a possible chemical effect of Salvadora persica chewing sticks. Evid. Based Complement. Alternat. Med., 2017, Article ID 2576548. https://doi.org/10.1155/2017/2576548 DOI: https://doi.org/10.1155/2017/2576548

Salem, M. Z.; Behiry, S. I.; Salem, A. Z. Effectiveness of root-bark extract from Salvadora persica against the growth of certain molecularly identified pathogenic bacteria. Microb. Pathog., 2018, 117, 320-326. https://doi.org/10.1016/j.micpath.2018.02.044 DOI: https://doi.org/10.1016/j.micpath.2018.02.044

Khan, M.; Alkhathlan, H. Z.; Khan, S. T. Antibiotic and antibiofilm activities of Salvadora persica L. essential oils against Streptococcus mutans: A detailed comparative study with chlorhexidine digluconate. Pathogens, 2020, 9(1), Art. No: 66. https://doi.org/10.3390/pathogens9010066 DOI: https://doi.org/10.3390/pathogens9010066

Ayoub, N.; Badr, N.; Al-Ghamdi, S. S.; Alzahrani, A.; Alsulaimani, R.; Nassar, A.; Swilam, N. GC/MS profiling and ex vivo antibacterial activity of Salvadora persica (siwak) against Enterococcus faecalis as intracanal medicament. Evid. Based Complement. Alternat. Med., 2021, Article ID 6333867. https://doi.org/10.1155/2021/6333867 DOI: https://doi.org/10.1155/2021/6333867

Alali, F.; Al-Lafi, T. GC-MS analysis and bioactivity testing of the volatile oil from the leaves of the toothbrush tree Salvadora persica L. Nat. Prod. Res., 2003, 17(3), 189-194. https://doi.org/10.1080/1057563021000040790 DOI: https://doi.org/10.1080/1057563021000040790

Elmhalli, F.; Garboui, S. S.; Borg-Karlson, A. K.; Mozūraitis, R.; Baldauf, S. L.; Grandi, G. The repellency and toxicity effects of essential oils from the Libyan plants Salvadora persica and Rosmarinus officinalis against nymphs of Ixodes ricinus. Exp. Appl. Acarol., 2019, 77, 585-599. https://doi.org/10.1007/s10493-019-00373-5 DOI: https://doi.org/10.1007/s10493-019-00373-5