Some biological activities and element levels of Lycoperdon pratense

Ali İmran Korkmaz; Celal Bal; Tetiana Krupodorova; Mehmet Ali Yüzbaşıoğlu; Beste Gizem Özbey Sarıdoğan; Mustafa Sevindik

doi:10.56782/pps.189

Published : 2024-05-10

Vol. 22 No. 2 (2024)

Some biological activities and element levels of Lycoperdon pratense

Ali İmran Korkmaz

Celal Bal

Tetiana Krupodorova

Mehmet Ali Yüzbaşıoğlu

Beste Gizem Özbey Sarıdoğan

Mustafa Sevindik

DOI: https://doi.org/10.56782/pps.189

Abstract

Mushrooms are natural products with many biological activities. In this study, antioxidant, antimicrobial, anticholinesterase activities and element levels of Lycoperdon pratense Pers. were determined. In this context, the mushroom was extracted with ethanol in a soxhlet device. Antioxidant potential was determined using Rel assay kits. Antimicrobial activity was determined using the agar dilution method. Antialzheimer activity was determined by acetyl- (AChE) and butyrylcholinesterase (BChE) potentials. The levels of elements accumulated in the mushroom were scanned using the wet digestion method. As a result of the analysis, the TAS value of the mushroom was measured as 2.589 ± 0.118 mmol Trolox equiv./L, the TOS value was 10.360 ± 0.197 µmol H₂O₂ equiv./L and the OSI value was 0.401±0.013. The mushroom extract was found to have high activity against bacteria. It was determined that the extract had an effect against microorganisms at concentrations between 50-400 μg/mL. It was determined that the anti-AChE IC50 value of the mushroom extract was 14.48 ± 0.80 μg/mL and the anti-BChE IC50 value was 23.10±1.21 μg/mL. It is also thought that it can be used as an indicator in terms of element levels within the mushroom. As a result, it was determined that the mushroom has antioxidant, antimicrobial and antiallergic potential.

Keywords:

Antimicrobial, antioxidant, Lycoperdon, Medicinal plants, antialzheimer

Most read articles by the same author(s)

Falah Saleh Mohammed, İmran Uysal, Mustafa Sevindik, A review on antiviral pants effective against different virus types , Prospects in Pharmaceutical Sciences: Vol. 21 No. 2 (2023)
Mustafa Sevindik, Falah Saleh Mohammed, Imran Uysal, Autism: plants with neuro-psychopharmacotherapeutic potential , Prospects in Pharmaceutical Sciences: Vol. 21 No. 3 (2023)
Ali İmran Korkmaz, Celal Bal, Emre Cem Eraslan, Mustafa Sevindik, Hasan Akgul, Biological activities of Agrocybe praecox (spring fieldcap mushroom) , Prospects in Pharmaceutical Sciences: Vol. 21 No. 4 (2023)
Mustafa Sevindik, Celal Bal, Emre Cem Eraslan, İmran Uysal, Falah Saleh Mohammed, Medicinal mushrooms: a comprehensive study on their antiviral potential , Prospects in Pharmaceutical Sciences: Vol. 21 No. 2 (2023)
Celal Bal, Emre Cem Eraslan, Mustafa Sevindik, Antioxidant, antimicrobial activities, total phenolic and element contents of wild edible mushroom Bovista nigrescens , Prospects in Pharmaceutical Sciences: Vol. 21 No. 2 (2023)
Falah Saleh Mohammed, Mustafa Sevindik, İmran Uysal, Ali Erdem Sabik, Quercetin: derivatives, biosynthesis, biological activity, pharmacological and therapeutic effects , Prospects in Pharmaceutical Sciences: Vol. 21 No. 3 (2023)
Falah Saleh Mohammed, Imran Uysal, Hasan Hüseyin Yaz, Mustafa Sevindik, Papaver species: usage areas, essential oil, nutrient and elements contents, biological activities , Prospects in Pharmaceutical Sciences: Vol. 21 No. 4 (2023)
Falah Saleh Mohammed, Imran Uysal, Mustafa Sevindik, Functional food Momordica charantia: biological activities , Prospects in Pharmaceutical Sciences: Vol. 21 No. 3 (2023)
Falah Saleh Mohammed, Eylem Kına, İmran Uysal, Mustafa Sevindik, Total phenolic, flavonoid contents, antioxidant and antimicrobial activities of Hesperis pendula , Prospects in Pharmaceutical Sciences: Vol. 21 No. 2 (2023)
Nuh Kormaz, Falah Saleh Mohammed, Imran Uysal, Mustafa Sevindik, Antioxidant, antimicrobial and anticholinesterase activity of Dittrichia graveolens , Prospects in Pharmaceutical Sciences: Vol. 21 No. 4 (2023)

1 2 > >>

Details

References

Statistics

Authors

Download files

PDF

Citation rules

Korkmaz, A. İmran, Bal, C., Krupodorova, T., Yüzbaşıoğlu, M. A., Özbey Sarıdoğan, B. G., & Sevindik, M. (2024). Some biological activities and element levels of Lycoperdon pratense. Prospects in Pharmaceutical Sciences, 22(2), 39–44. https://doi.org/10.56782/pps.189

Altmetric indicators

Cited by / Share

Licence

This work is licensed under a Creative Commons Attribution 4.0 International License.

References

Mohammed, F.S.; Uysal, I.; Sevindik, E.; Doğan, M.; Sevindik, M. Pimpinella species (Anise): Traditional use, Mineral, Nutrient and Chemical contents, biological activities. Int. J. Tradit. Complement. Med. Res. 2023, 4(2), 97-105. https://doi.org/10.53811/ijtcmr.1306831 DOI: https://doi.org/10.53811/ijtcmr.1306831

Sevindik, M.; Bal, C.; Eraslan, E.C.; Uysal, I.; Mohammed, F.S. Medicinal mushrooms: a comprehensive study on their antiviral potential. Prosp. Pharm. Sci. 2023; 21(2), 42-56. https://doi.org/10.56782/pps.141 DOI: https://doi.org/10.56782/pps.141

Uysal, I.; Koçer, O.; Mohammed, F.S.; Lekesiz, Ö.; Doğan, M.; Şabik, A.E.; Sevindik, E.; Gerçeker, F.O.; Sevindik, M. Pharmacological and Nutritional Properties: Genus Salvia. Adv. Pharmacol. Pharm. 2023, 11(2), 140-155. http://dx.doi.org/10.13189/app.2023.110206 DOI: https://doi.org/10.13189/app.2023.110206

Sevindik, M.; Akgül, H.; Günal, S.; Doğan, M. Pleurotus ostreatus’ un doğal ve kültür formlarının antimikrobiyal aktiviteleri ve mineral madde içeriklerinin belirlenmesi. Kastamonu Univ. J. For. Fac. 2016, 16(1), 153-156. http://dx.doi.org/10.17475/kujff.27130 DOI: https://doi.org/10.17475/kujff.27130

Lindequist, U.; Niedermeyer, T.H.; Jülich, W.D. The pharmacological potential of mushrooms. Evid. Based. Complement. Alternat. Med. 2005, 2, 285-299. https://doi.org/10.1093/ecam/neh107 DOI: https://doi.org/10.1093/ecam/neh107

Weng, Y.; Lu, J.; Xiang, L.; Matsuura, A.; Zhang, Y.; Huang, Q.; Qi, J. Ganodermasides C and D, two new anti-aging ergosterols from spores of the medicinal mushroom Ganoderma lucidum. Biosci. Biotechnol. Biochem. 2011, 75(4), 800-803. https://doi.org/10.1271/bbb.100918 DOI: https://doi.org/10.1271/bbb.100918

Alves, M.J.; Ferreira, I.C.; Dias, J.; Teixeira, V.; Martins, A.; Pintado, M. A review on antimicrobial activity of mushroom (Basidiomycetes) extracts and isolated compounds. Planta. Med., 2012, 78(16), 1707-1718. https://doi.org/10.1055/s-0032-1315370 DOI: https://doi.org/10.1055/s-0032-1315370

Eraslan, E.C.; Altuntas, D.; Baba, H.; Bal, C.; Akgül, H.; Akata, I.; Sevindik, M. Some biological activities and element contents of ethanol extract of wild edible mushroom Morchella esculenta. Sigma J. Engin. Nat. Sci. 2021, 39(1), 24-28.

Saridogan, B.G.O.; Islek, C.; Baba, H.; Akata, I.; Sevindik, M. Antioxidant antimicrobial oxidant and elements contents of Xylaria polymorpha and X. hypoxylon (Xylariaceae). Fresen. Environ. Bull. 2021, 30(5), 5400-5404.

Karalti, I.; Kabaktepe, S.; Akata, I.; Uysal, I.; Saridogan, B.G.O.; Sevindik, M. Antioxidant, antimicrobial potentials and element levels of Laccaria laccata. Fresen. Environ. Bull. 2022, 31(9), 9621-9626.

Krupodorova, T.; Barshteyn, V.; Sevindik, M. Antioxidant and antimicrobial potentials of mycelial extracts of Hohenbuehelia myxotricha grown in different liquid culture media. BioTechnologia, 2022, 103(1), 19-28. https://doi.org/10.5114/bta.2022.113912 DOI: https://doi.org/10.5114/bta.2022.113912

Bal, C.; Eraslan, E.C.; Sevindik, M. Antioxidant, Antimicrobial Activities, Total Phenolic and Element Contents of Wild Edible Mushroom Bovista nigrescens. Prosp. Pharm. Sci. 2023, 21(2), 37-41. https://doi.org/10.56782/pps.139 DOI: https://doi.org/10.56782/pps.139

Erel, O. A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. Clin. Biochem., 2004, 37(4), 277-285. https://doi.org/10.1016/j.clinbiochem.2003.11.015 DOI: https://doi.org/10.1016/j.clinbiochem.2003.11.015

Erel, O. A new automated colorimetric method for measuring total oxidant status. Clin. Biochem., 2005, 38(12), 1103-1111. https://doi.org/10.1016/j.clinbiochem.2005.08.008 DOI: https://doi.org/10.1016/j.clinbiochem.2005.08.008

Sevindik, M. The novel biological tests on various extracts of Cerioporus varius. Fresen. Environ. Bull., 2019, 28(5), 3713-3717.

Bauer, A.W.; Kirby, W.M.; Sherris, J.C.; Turck, M. Antibiotic susceptibility testing by a standardized single disk method. Am. J. Clin. Path., 1966, 45, 493-96. DOI: https://doi.org/10.1093/ajcp/45.4_ts.493

Hindler, J.; Hochstein, L.; Howell, A. Preparation of routine media and reagents used in antimicrobial susceptibility testing. Part 1. McFarland standards, p. 5.19.1-5.19.6. In H. D. Isenberg (ed) Clinical microbiology procedures handbook, vol. 1. American Society for Microbiology, Washington, D.C. 1992.

Matuschek, E.; Brown, D.F.; Kahlmeter, G. Development of the EUCAST disk diffusion antimicrobial susceptibility testing method and its implementation in routine microbiology laboratories. Clin. Microbiol. Infect., 2014, 20(4), 255-266. https://doi.org/10.1111/1469-0691.12373 DOI: https://doi.org/10.1111/1469-0691.12373

Baba, H.; Sevindik, M.; Dogan, M.; Akgül, H. Antioxidant, antimicrobial activities and heavy metal contents of some Myxomycetes. Fresen. Environ. Bull., 2020, 29(09), 7840-7846.

Ellman, G.L.; Courtney, K.D.; Anders, V.J.; Featherstone, R.M. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem. Pharma., 1961, 7(88), 951-961. https://doi.org/10.1016/0006-2952(61)90145-9 DOI: https://doi.org/10.1016/0006-2952(61)90145-9

Akgül, H.; Sevindik, M.; Akata, I.; Altuntaş, D.; Bal, C.; Doğan, M. Macrolepiota procera (Scop.) Singer. mantarının ağır metal içeriklerinin ve oksidatif stres durumunun belirlenmesi. Süleyman Demirel Üniv. Fen Bilim. Enst. Derg. 2016, 20(3), 504-508. https://doi.org/10.19113/sdufbed.56964 DOI: https://doi.org/10.19113/sdufbed.56964

Unal, O; Eraslan, E.C.; Uysal, I.; Mohammed, F.S.; Sevindik, M.; Akgul, H. Biological activities and phenolic contents of Rumex scutatus collected from Turkey. Fresen. Environ. Bull. 2022, 31(7), 7341-7346.

Korkmaz, N.; Dayangaç, A.; Sevindik, M. Antioxidant, antimicrobial and antiproliferative activities of Galium aparine. J. Fac. Pharm. Ankara 2021, 45(3), 554-564. http://dx.doi.org/10.33483/jfpau.977776 DOI: https://doi.org/10.33483/jfpau.977776

Bal, C.; Baba, H.; Akata, I.; Sevindik, M.; Selamoglu, Z.; Akgül, H. Biological Activities of Wild Poisonous Mushroom Entoloma sinuatum (Bull.) P. Kumm (Boletales). KSU J. Agric. Nat. 2022, 25(1), 83-87. http://dx.doi.org/10.18016/ksutarimdoga.vi.880151 DOI: https://doi.org/10.18016/ksutarimdoga.vi.880151

Kalkan, M.; Aygan, A.; Çömlekçioglu, N.; Çömlekçioğlu, U. Olea europaea Yapraklarının Bazı Biyoaktif Özelliklerinin Araştırılması, Antimikrobiyal ve Enzim İnhibisyon Etkinliğinin İncelenmesi. Turkish JAF Sci. Tech. 2023, 11(3), 496-504. http://dx.doi.org/10.24925/turjaf.v11i3.496-504.5828 DOI: https://doi.org/10.24925/turjaf.v11i3.496-504.5828

Çömlekçioğlu, N.; Çırak, R. Comparison of fatty acid composition and antioxidant contents of Tribulus terrestris L. collected from different localities. Turkish JAF Sci. Tech. 2021, 9(8), 1448-1454. https://doi.org/10.24925/turjaf.v9i8.1448-1454.4273 DOI: https://doi.org/10.24925/turjaf.v9i8.1448-1454.4273

Comlekcioglu N, Dağlı F, Çömlekcioğlu U, Aygan A. Cornus mas ve Rosa canina Meyvelerinin Antioksidan Kapasitesi ve Bazı Fitokimyasal Özellikleri. Turkish JAF Sci. Tech. 2022, 10(9), 1724-1731. http://dx.doi.org/10.24925/turjaf.v10i9.1724-1731.5434 DOI: https://doi.org/10.24925/turjaf.v10i9.1724-1731.5434

Bal, C.; Akgül, H.; Sevindik, M. The Antioxidant potential of ethanolic extract of edible mushroom Lycoperdon molle Pers. (Agaricomycetes). Eurasian J. For. Sci. 2019, 7(3), 277-283. https://doi.org/10.31195/ejejfs.591432 DOI: https://doi.org/10.31195/ejejfs.591432

Krupodorova, T.; Sevindik, M. Antioxidant potential and some mineral contents of wild edible mushroom Ramaria stricta. AgroLife Sci. J. 2020, 9(1), 186-191

Sevindik, M. Antioxidant activity of ethanol extract of Daedaleopsis nitida medicinal mushroom from Turkey. Mycopath, 2018, 16(2), 47-49.

Sevindik, M.; Pehlivan, M.; Dogan, M.; Selamoglu, Z. Phenolic content and antioxidant potential of Terfezia boudieri. Gazi Univ. J. Sci., 2018, 31(3), 707-711.

Sevindik, M.; Akata, I. Antioxidant, oxidant potentials and element content of edible wild mushroom Helvella leucopus. Indian J. Nat. Prod. Resour. 2020, 10(4), 266-271. doi: 10.56042/ijnpr.v10i4.25215

Mushtaq, W.; Baba, H.; Akata, I.; Sevindik, M. Antioxidant potential and element contents of wild edible mushroom Suillus granulatus. KSU J. Agric. Nat. 2020, 23(3), 592-595. https://doi.org/10.18016/ksutarimdoga.vi.653241 DOI: https://doi.org/10.18016/ksutarimdoga.vi.653241

Özaltun, B.; Sevindik, M. Evaluation of the effects on atherosclerosis and antioxidant and antimicrobial activities of Agaricus xanthodermus poisonous mushroom. Eur. J. Res. 2020, 6(6), 539-544. https://doi.org/10.18621/eurj.524149 DOI: https://doi.org/10.18621/eurj.524149

Sevindik, M.; Bal, C. Antioxidant, antimicrobial, and antiproliferative activities of wild mushroom, Laeticutis cristata (Agaricomycetes), from Turkey. Int. J. Med. Mushrooms 2021, 23(11), 85-90. https://doi.org/10.1615/intjmedmushrooms.2021040415 DOI: https://doi.org/10.1615/IntJMedMushrooms.2021040415

Sevindik, M.; Mohammed, F.S.; Uysal, I. Autism: plants with neuro-psychopharmacotherapeutic potential. Prosp. Pharm. Sci. 2023, 21(3), 38-48. https://doi.org/10.56782/pps.143 DOI: https://doi.org/10.56782/pps.143

Sevindik, M. Anticancer, antimicrobial, antioxidant and DNA protective potential of mushroom Leucopaxillus gentianeus (Quél.) Kotl. Indian J. Exp. Biol. 2021, 59(05), 310-315. https://doi.org/10.56042/ijeb.v59i05.50501 DOI: https://doi.org/10.56042/ijeb.v59i05.50501

Akyüz, M.; İnci, Ş.; Kırbağ, S. Evaluation of Antimicrobial, Antioxidant, Cytotoxic and DNA Protective Effects of Oyster Mushroom: Pleurotus pulmonarius (Fr.) Quel. Arab. J. Sci. Eng. 2023, 48(6), 7273-7283. http://dx.doi.org/10.1007/s13369-022-07418-9 DOI: https://doi.org/10.1007/s13369-022-07418-9

Çolak, S.; Dağlı, F.; Çömlekcioğlu, N.; Kocabaş, Y.Z.; Aygan, A. Antimicrobial activity and some phytochemical properties of extracts from Achillea aleppica subsp. aleppica. J. Food 2020, 45(5), 929-941. https://doi.org/10.15237/gida.GD20048 DOI: https://doi.org/10.15237/gida.GD20048

Jonathan, S.G.; Fasidi, I.O. Antimicrobial activities of two Nigerian edible macro-fungi-Lycoperdon pusilum (Bat. Ex) and Lycoperdon giganteum (Pers.). Afr. J. Biomed. Res. 2003, 6(2), 85-90. https://doi.org/10.4314/ajbr.v6i2.54029 DOI: https://doi.org/10.4314/ajbr.v6i2.54029

Akpi, U.K.; Odoh, C.K.; Ideh, E.E.; Adobu, U.S. Antimicrobial activity of Lycoperdon perlatum whole fruit body on common pathogenic bacteria and fungi. African J. Clin. Exp. Microbiol. 2017, 18(2), 79-85. http://dx.doi.org/10.4314/ajcem.v18i2.4 DOI: https://doi.org/10.4314/ajcem.v18i2.4

Canli, K.; Altuner, E.; Akata, I.; Turkmen, Y.; Uzek, U. In vitro antimicrobial screening of Lycoperdon lividum and determination of the ethanol extract composition by gas chromatography/mass spectrometry. Bangladesh J. Pharmacol. 2016, 11(2), 389-384. http://dx.doi.org/10.3329/bjp.v11i2.26369 DOI: https://doi.org/10.3329/bjp.v11i2.26369

Konrath, E.L.; Passos, C.D.S.; Klein-Júnior, L.C.; Henriques, A.T. Alkaloids as a source of potential anticholinesterase inhibitors for the treatment of Alzheimer's disease. J. Pharm. Pharmacol. 2013, 65(12), 1701-1725. https://doi.org/10.1111/jphp.12090 DOI: https://doi.org/10.1111/jphp.12090

Li, N.; Li, H.; Liu, Z.; Feng, G.; Shi, C.; Wu, Y. Unveiling the Therapeutic Potentials of Mushroom Bioactive Compounds in Alzheimer’s Disease. Foods 2023, 12(15), 2972. https://doi.org/10.3390/foods12152972 DOI: https://doi.org/10.3390/foods12152972

Świątek, Ł.; Sieniawska, E.; Sinan, K.I.; Maciejewska-Turska, M.; Boguszewska, A.; Polz-Dacewicz, M.; Senkardes, I.; Guler, G.O.; Sadeer, N.B.; Mahomoodally, M.F.; Zengin, G. LC-ESI-QTOF-MS/MS Analysis, Cytotoxic, Antiviral, Antioxidant, and Enzyme Inhibitory Properties of Four Extracts of Geranium pyrenaicum Burm. f.: A Good Gift from the Natural Treasure. Int. J. Mol. Sci. 2021, 22(14), 7621. https://doi.org/10.3390%2Fijms22147621 DOI: https://doi.org/10.3390/ijms22147621

Karaltı, İ.; Eraslan, E.C.; Sarıdoğan, B.G.Ö.; Akata, I.; Sevindik M. Total Antioxidant, Antimicrobial, Antiproliferative Potentials and Element Contents of Wild Mushroom Candolleomyces candolleanus (Agaricomycetes) from Turkey. Int. J. Med. Mushrooms 2022, 24(12), 69-76. https://doi.org/10.1615/intjmedmushrooms.2022045389 DOI: https://doi.org/10.1615/IntJMedMushrooms.2022045389

Uzun, Y.; Genccelep, H.; Kaya, A.; Akcay, M.E. The mineral contents of some wild edible mushrooms. Ekoloji 2011, 20(80), 6-12. http://dx.doi.org/10.5053/ekoloji.2011.802

Sarikurkcu, C.; Copur, M.; Yildiz, D.; Akata, I. Metal concentration of wild edible mushrooms in Soguksu National Park in Turkey. Food Chem. 2011, 128(3), 731-734. http://dx.doi.org/10.1016/j.foodchem.2011.03.097 DOI: https://doi.org/10.1016/j.foodchem.2011.03.097

Zhu, F.; Qu, L.; Fan, W.; Qiao, M.; Hao, H.; Wang, X. Assessment of heavy metals in some wild edible mushrooms collected from Yunnan Province, China. Environ. Monit. Assess. 2011, 179, 191-199. https://doi.org/10.1007/s10661-010-1728-5 DOI: https://doi.org/10.1007/s10661-010-1728-5

Korkmaz, A. I., Bal, C., Eraslan, E. C., Sevindik, M., & Akgul, H. (2023). Biological activities of Agrocybe praecox (spring fieldcap mushroom). Prosp. Pharm. Sci. 2023, 21(4), 33-39. https://doi.org/10.56782/pps.156 DOI: https://doi.org/10.56782/pps.156

Sevindik, M.; Ajaz, M.; Özdemir, B.; Akata, I.; Selamoğlu, Z. Oxidant/antioxidant potentials and heavy metal levels of Pisolithus arhizus and its effects on cardiovascular diseases. Indian J. Nat. Prod. Resour. 2021, 12(4), 600-604.